新生血管形成

中度酸烧伤损伤波及基质层，角膜伤口愈合时间较长，愈合后角膜留下薄翳，有少量新生血管形成；

In moderate acid-burn cornea , the damage could be seen both in corneal epithelium and stroma , and it took more time for corneal wound to heal . Thin nebula and a little of CNV left after corneal wound healing .

结论糖尿病兔模型中，视网膜Müller细胞通过表达VEGF发挥促进新生血管形成的作用。

Conclusion Retinal M ü ller cell plays the role of acceleration of neovascularization through VEGF expression in experimental diabetic rabbit retina .

征象相比，CT征象的综合分型可以更准确地反映肿瘤内新生血管形成状况；

As compared with single CT characteristic , comprehensive types of CT features can predicate tumor neovascularization more accurately .

VEGF、NO在角膜碱烧伤新生血管形成中的影响

Expressions of VEGF and NO in cornea with neovascularization after alkali burn

抗肿瘤新生血管形成作用的靶点Bcl-2蛋白

Bcl-2 Protein , a new anti-angiogenesis target

视网膜微循环内微血管病变伴血栓形成及新生血管形成在DR的发生发展中起重要的作用。

Microangiopathy companyed by thrombopoiesis and neovascularization of retina were very important in the development of DR.

结论VEGF诱导的新生血管形成能够使角质细胞迁移进入中耳腔。

Conclusions Angiogenesis induced by VEGF can support the sustained migration of keratinocytes into the middle ear cavity .

iNOS在碱烧伤角膜新生血管形成中的表达及意义

Expression and Significance of iNOS in Rat Corneal Neovascularization After Alkaline Burn

血管内皮生长因子（VEGF）直接作用于内皮细胞参予新生血管形成，成为血管形成过程中最重要的成血管生长因子。

Vascular endothelial growth factor ( VEGF ) became the most important factor for directly effect on endothelial cells in angiogenesis .

CD34高表达是新生血管形成活跃的表现，说明肿瘤组织的高增殖性；

The higher expression of CD34 showed active angiogenesis , indicating higher proliferation of tumor tissue .

目的探讨VEGF反义核酸作为抗新生血管形成药物和抗肿瘤药物的可能性。

Objective To investigate whether antisense oligodeoxynucletides ( ODNs ) of VEGF can become a kind of drugs for antitumor cancer treatment .

抑制新生血管形成，可达到防治ROP的目的。

Angiogenesis inhibition can be achieved the purpose of combating ROP .

MMP-2、TIMP-2与碱烧伤后角膜新生血管形成的实验研究

The experimental study on MMP-2 and TIMP-2 in corneal neovascularization of rats after alkali burn

综合分析VEGF及其受体的表达有助于对判断结直肠癌侵袭能力和新生血管形成的判断。

The comprehensive analysis of the expression of VEGF and its receptors is advantageous to estimate invasive ability and angiogenesis in colorectal cancers .

视网膜新生血管形成和黄斑水肿是糖尿病视网膜病变（Diabeticretinopathy，DR）的主要临床表现，也是DR主要的致盲原因。

Retinal neovascularization and macular edema are the main clinical signs of diabetic retinopathy ( DR ), and also the causes of blindness .

TNFα可促进新生血管形成，并能减轻免疫反应及在低浓度情况下有刺激成骨作用。

TNF α had stimulative effects on bone formation at lower concentration and neovascularization . TNF α was supposed to reduce immune respones as well .

VEGF和Flk-1不是影响肿瘤新生血管形成的惟一因素。

The VEGF , Flk-2 are not the single angiogenesis factors of inducing tumour new vessel .

血管内皮生长因子（VascularEndothelialGrowthFactor，VEGF）是被公认的作用最强的促内皮细胞生长因子，在肿瘤的新生血管形成中成为最关注的因素。

Up to date , the most potent growth factor of endothelium is vascular endothelial growth factor ( VEGF ), which plays important roles in the regulation of metastasis of malignancy .

不同能量半导体激光对大鼠脉络膜新生血管形成的影响Survivin及VEGF在脉络膜黑色素瘤的表达及其与血管形成的关系

Influence of different power on diode laser-induced choroidal neovascularization model in rats Relationship of survivin and VEGF with angiogenesis in choroidal melanoma

结论在视网膜新生血管形成中存在HIF-1α、COX-2的高表达，且二者表达密切相关。

Conclusion Over-expressions of HIF-1 α and COX-2 are found in and are closely correlated with the retinal neovascularization .

目前，动物实验已证实，脑缺血时脑内可见新生血管形成，而CO中毒后脑血管的新生情况尚无明确报道。

At present , the animal experimentation confirmed that the angiogenesis after the cerebral ischemia . But there was not explicit reported about the angiogenesis after the CO poisoning .

目的探讨奥曲肽对角膜新生血管形成及角膜内血管内皮生长因子（VascularEndothelialGrowthFactor，VEGF）和色素上皮衍生因子（pigmentepitheliumderivedfactor，PEDF）表达的影响。

Objective To discuss the inhibitive effects of Octreotide on angiogenesis and expressions of vascular endothelial growth factor ( VEGF ) and pigment epithelium derived factor ( PEDF ) .

由Müller细胞衍生的VEGF，是血管渗漏、视网膜前及视网膜内病理性新生血管形成的主要因素。

M ü ller cell-derived VEGF is a major factor contributes to vascular leakage and pathological neovascularization of retina .

DR是一种微血管病变，其基本特征包括周细胞选择性丧失、毛细血管基底膜增厚、通透性增加和新生血管形成。

The pathological manifestations of diabetic retinopathy are the selective loss of pericytes , capillaries endothelial basement membrane thickening , increase in vasopermeability and retinal neovascularization .

结论Ang2，HIF-1α和VEGF与肝癌的新生血管形成有关；

Conclusions HIF - α、 angiopoietin and VEGF are possible angiogenic factors in the angiogenesis in HCC .

反应停对肿瘤的敏感性原因分析显示反应停的抗肿瘤作用并不依赖于其抗新生血管形成作用，但与肿瘤细胞中COX-2表达密切相关。

The cause analysis of sensitivity to thalidomide displayed that the antitumor of thalidomide was associated with COX-2 expressing in tumor independent of antiangiogenesis .

已有研究表明，MMP-2、MMP-9与肿瘤浸润、肝纤维化以及新生血管形成密切相关。

It was reported that MMP - 2 and MMP - 9 were closely correlated with tumour metastasis , hepatic fibrosis and tumor angiogenesis .

研究结果表明：肝细胞肝癌的新生血管形成中，TGF-β1或缺氧都起到了促进VEGF表达的作用，并且TGF-β1能够协同缺氧上调VEGF的表达；

Our findings suggest that Both TGF - β 1 and hypoxia can stimulate the VEGF expression and TGF-pi can cooperate with hypoxia to stimulate VEGF expression in HCC .

结论COX-2参与角膜新生血管形成，选择性COX-2抑制剂NS-398可明显抑制碱烧伤引起的角膜新生血管的生长，其抑制效果呈剂量依赖性。

Topical application of COX-2 inhibitor NS-398 eye drops has prominent effectiveness on the inhibition of angiogenesis induced by alkali burn .

环氧合酶-2抑制剂Rofecoxib抑制小鼠视网膜新生血管形成的实验研究

The Effects of COX-2 Inhibition Rofecoxib on Retinal Angiogenesis in the Mouse