鼻病毒

人鼻病毒3C蛋白酶基因的克隆、表达、纯化及活性

Gene Cloning , Expression , Purification and Activity of Human Rhinovirus 3C Protease

兰格计划进一步分析受试者的唾液，看其中是否确实存在鼻病毒，而不只是偏高的IgA抗体水平。

Langer plans to further analyze the subjects " saliva to see whether they actually have the rhinovirus and not just elevated IgA .

绝大多数的感冒是由鼻病毒引起的。

Most colds are caused by rhinoviruses .

一步法RT-PCR从临床样本中检测到鼻病毒基因

Detection of human rhinovirus genes from clinical sample by one-step RT-PCR

巢式PCR诊断儿科患者鼻病毒感染的探讨

Human rhinovirus detection from infants and young children with acute respiratory infections by nested-polymerase chain reaction

德国研究人员说，SARS病原体中一种重要的酶在结构和功能上与一种造成感冒的鼻病毒相似。

German researchers say an important enzyme in the SARS pathogen is similar in structure and function to one found in cold-causing rhinoviruses .

现在，兰格计划进一步分析受试者的唾液，看其中是否确实存在鼻病毒，而不只是偏高的IgA抗体水平。

Langer plans to further analyze the subjects ' saliva to see whether they actually have the rhinovirus and not just elevated IgA .

目的了解儿科急性呼吸道感染的病毒病原，建立快速、敏感、特异的检测鼻病毒（HRV）的方法。

Objective To develop a rapid , sensitive and specific method for detection human rhinovirus ( HRV ) from clinical specimens .

然而进一步研究显示，只有人鼻病毒（HRV）感染与哮喘发作明显相关，OR为2.38。

However , further analysis revealed that only human rhinovirus ( HRV ) infection was significantly associated with asthma attacks , at an OR of2.38 .

目的人鼻病毒3C蛋白酶具有酶切物异性强且在低温下仍保持较强酶活性的特点而被用作工具酶。

Objective Application of human rhinovirus 14 3C protease as a tool-enzyme for more stringent sequence specificity and efficient cleavage at low temperature .

哮喘发作患者病毒检测阳性为59例，鼻病毒为23例，流感病毒A和B为18例。结论临床缓解期患者并发上感后哮喘发作的比例为61.8%，3天后发作比例约为85.3%。

Rhinovirus ( RV ) were found in 23 patients , and influenza virus A and B ( IFAV ) in 18.Conclusion Asthma attacks rate among stable asthma patients with upper respiratory tract viral infection was 61.8 % , and it was 85 . % after 3 days .

Pirodavir（R77975）是由Janssen研究基金会发现的。这个化合物有抑制许多鼻病毒血清型复制的显著活性。

Pirodavir ( R77975 ) was discovered at Janssen Research Foundation .

帕尔门伯格博士指出，鼻病毒附着在细胞间黏附分子（ICAM）受体上以便进入壁细胞，在该受体张开时，人们才会感染病毒。

To get infected , the so-called ICAM receptors , which the rhinovirus attaches to in order to enter the nasal cells , need to be open , Dr. Palmenberg said .

麦凯博士表示，这个想法从生物学角度来看其实是可行的，鼻病毒和其他呼吸道RNA病毒将会被免疫系统彻底清除，在被感染后人们也不会跑到其他地方去。

Dr. Mackay said that this idea is actually somewhat reasonable , from a purely biological point of view . He said that rhinoviruses-and other RNA respiratory viruses-are completely eliminated from the body by the immune system ; they do not linger after infection .

HRV-A及HRV-C核苷酸序列同源性较低，亲缘关系稍远，提示此次研究期间北京地区存在多条鼻病毒传播链。

The nucleotide sequence homology of HRV-A and C was low and their genetic relationship was a little further , suggesting more than one propagating chain of human rhinoviruses .

在这种情况下，人类鼻病毒也会消亡。

in that case , human rhinoviruses would die with us .

复方干扰素合剂抗鼻病毒的研究

Study on Anti-rhinoviral Effect of A Compound IFN Mixture

他们随后被隔离，在指导下服用含有感冒病毒的鼻病毒。

They were then quarantined and administered nasal drops containing the common-cold-causing rhinovirus .

这些免疫功能不健全的人会成为鼻病毒的安全乐园。

This small group of immunocompromised people would serve as safe havens for rhinoviruses .

支气管鼻病毒感染与儿童哮喘发病的关系

Relationship between Rhinovirus Infection and Asthma in Children

三分之一至一半的普通感冒都由鼻病毒引起。

They are responsible for anywhere between a third and half of all common colds .

如果鼻病毒不能找到足够多的人进行传播，它最终就会消亡。

If rhinoviruses don 't have enough humans to move between , they die out .

目的：探讨儿童哮喘发作与鼻病毒感染的关系。

Objective To explore the relationship of rhinovirus ( RV ) with asthma exacerbation in children .

在测试的旅馆中150件物品表面有35%检测到鼻病毒。

They detected rhinovirus on35 percent of a total of150 surfaces tested in the hotel rooms .

结果：准确检测到重症哮喘患者房间内的鼻病毒；

Results : The filter samples in the ward of patient with severe asthma syndrome were rhinovirus-positive ;

然而，系统筛查鼻病毒可以改变我们的认识并重新反思这个说法。

However , systematic screening for rhinovirus could change perceptions and lead us to revisit this dogma .

研究期间鼻病毒感染发生在2008年冬季和2009年、2010年春季。

Human rhinoviruses infection occurred in the winter of 2008 and the spring of 2009 and 2010 .

0~1岁儿童，特别是6月龄及以下婴幼儿是鼻病毒的易感人群。

Children aged 0 to 1 , especially six months and younger were more susceptible to human rhinoviruses .

但如果有人发明出了鼻病毒疫苗的话，我一定会第一时间去接种的。

But if they ever come up with a rhinovirus vaccine , I 'll be first in line .

疾病爆发的准确原因不得而知，但鼻病毒很有可能是其中很多起咳嗽爆发的元凶。

The exact cause of the outbreaks is unknown , but rhinoviruses were probably responsible for many of them .