适应性免疫应答

适应性免疫应答的启动需要DC的抗原提呈。

Adaptive immune response is conditional upon angtigen presentation of DC .

而巨噬细胞参与调节适应性免疫应答相关的分子的基因表达如：IL-1、TNF-α、IL-12等表达无明显差异。

And there was no significant difference about the molecular expression involved in the regulation of the adaptive immune response such as : IL-1 , TNF - α, IL-12 .

《国际肝病》：宿主和病毒因素都参与了慢性HCV感染以及固有和适应性免疫应答逃避。

Hepatology Digest : Both host and viral factors are involved in chronic HCV infection , and escape from innate and adaptive immune responses .

AM作为吞噬细胞吞噬、杀死和消化微生物，是固有免疫的重要组成部分，在适应性免疫应答的多个阶段中发挥重要作用，其功能状态可影响ALI的发生发展。

AM as phagocytes phagocytosis which can kill and digest microorganisms , and involving in multiple stages of the adaptive immune response , its functional status can affect the occurrence and development of ALI .

随着Toll样受体（TLR）的发现，固有免疫应答如何调控适应性免疫应答已成为研究的热点。

Recently , with the discovery of the Toll-like receptors ( TLR ), the role of innate immune responses in the control of adaptive immunity has become a new area of interest .

TLR4是PRR的一个重要成员，在CNS主要表达在小胶质细胞，且在CNS固有免疫和适应性免疫应答的启动中扮演重要的角色。

Toll-like receptor ( TLR ) 4 , an important member of PRR , is expressed mainly by microglia , and plays important role in innate immune reaction in the CNS .

有研究提示，在SLE小鼠中，显著激活的巨噬细胞和其它髓系细胞大量浸润到淋巴组织和肾脏中，启动和促进适应性免疫应答，从而导致SLE的发生。

It was reported that markedly activated macrophages and other myeloid cells which infiltrated in lymphoid tissues and kidneys , mediated the onset and propagation of an aggressive adaptive immune response , thereby leading to SLE pathogenesis in mice .

鱼类具备两种基本的免疫应答类型：先天性免疫应答和适应性免疫应答。

Fish immune system contains innate immune response and acquired immune response .

了解抗炎症因子对活化的肝脏非实质细胞介导的适应性免疫应答的作用及可能的机制。

To learn the function and possible mechanism of the anti-inflammatory cytokines against the liver non-parenchymal cells mediated adaptable immunity response . 3 .

巨噬细胞是启动固有免疫应答的主要力量，并启动稍后的适应性免疫应答。

Macrophages have a central role in initiating the innate immune response , which leads to activation of the adaptive response in the later phase .

免疫记忆是适应性免疫应答的重要特征，其细胞学基础的阐明是疫苗开发和疾病预防的关键。

Immunological memory is an important characteristic of adaptive immune response and elucidation of its cellular basis is critical for vaccine exploration and disease prevention .

活化的巨噬细胞可以作为抗原提呈细胞启动适应性免疫应答，进而诱导T细胞活化、增殖、分化为效应细胞。

Activated macrophage can initiate the acquired immune responses as a antigen presenting cell . Then T lymphocytes become activated , proliferated and then differentiated into effective lymphocytes , induced by activated macrophages .

然后根据适应性免疫应答的过程提取出了免疫优化原理和免疫反馈原理，并把它们同控制系统相结合。

On the basis of the process of the adaptive immune response , this paper abstracts the immune optimization principle and the immune feedback principle , then integrates them with the control system .

本文对生物免疫系统的主要生理功能&免疫应答进行了深入的学习和分析，并重点研究了免疫应答当中的适应性免疫应答。

This paper learns and analyses the main physiological function of the biology immune system & immune response deeply , and researches on the process of the adaptive immune response in the immune response .

然后模拟生物适应性免疫应答过程，通过扩展操作在群体中较优秀个体的小邻域内进行局部搜索，同时利用突变操作在较差个体的大邻域内搜索；

Then , simulating the process of biology adaptive immune response , expansion operation was used to perform local searching in a small neighborhood of the better individuals in population , and mutation operation was used to search in a large neighborhood of the worse individuals .