新生儿败血症

16SRRNA基因检测在新生儿败血症早期诊断中的研究进展

Progress about the Detection of 16S rRNA Gene in the Diagnosis of Neonatal Septicemia

方法采用鼠成纤维细胞（L929）生物活性法测定了52例新生儿败血症病人的血浆TNF水平。

Method Plasma TNF levels of52 cases of neonatal septicemia were assayed by L929 cell biological activity method .

86例新生儿败血症血清降钙素原和C反应蛋白的水平研究

Study on levels of serum procalcitonin and C-reactive protein in neonatal sepsis patients

抗生素预防与非B族链球菌感染的新生儿败血症

Antibiotic prophylaxis and non-group B streptococcal neonatal sepsis

早、晚发两组新生儿败血症革兰阳性菌的感染率有显著统计学差异（P＜0.05）。

There was statistically significant difference in the detection rate for gram positive bacteria infections between EONS and LONS ( P0.05 ) .

超敏CRP及IL-6水平变化在新生儿败血症诊治中的价值

Value of determination of Hs-CRP and IL-6 in blood to diagnose neonate hematosepsis

血清IL-6、CRP、PCT水平对新生儿败血症的诊断价值

Diagnostic value of serum interleukin-6 , C-reactive protein and procalcitonin on neonatal sepsis

目的评价血清中白介素-6（IL-6）检测对于早期诊断新生儿败血症的价值。

Objective To assess the value of interleukin-6 ( IL-6 ) in eary diagnosis of newborns with sepsis .

IL-6及CRP在早期诊断新生儿败血症中的临床研究

Clinical and Lab Studies on the value of IL-6 and CRP in Early Diagnose of Neonatal Sepsis

16SRRNA基因芯片诊断新生儿败血症

Using of 16S rRNA gene chip hybridization in the diagnosis of neonatal sepsis

目的探索新生儿败血症的早期诊断手段，评价白细胞介素6（IL-6）和C反应蛋白（CRP）在新生儿败血症早期诊中的临床价值。

Objective To investigate the value of Interleukin - 6 ( IL-6 ) and C-reactive protein ( CRP ) on early diagnose of neonatal sepsis .

结论同步换血疗法对新生儿败血症合并MODS有较好的疗效。

Conclusion The exchange transfusion as a simple blood purification method is effective on neonate septicemia with MODS .

中性粒细胞粘附分子CD（11b）表达对新生儿败血症早期诊断价值的研究

Expression of neutrophil adhesion molecule CD_ ( 11b ) as an early diagnostic marker for neonatal sepsis

目的探讨换血疗法对新生儿败血症合并多器官功能障碍综合征（MODS）的疗效。

Objective To explore the efficacy of exchange transfusion in septic neonate with multiple organ dysfunction syndrome ( MODS ) .

结论16SRRNA基因PCR加基因芯片杂交可为新生儿败血症提供早期、敏感的病原学诊断依据。

Conclusions 16S rRNA gene amplification plus gene chip hybridization is an early and sensitive method in pathogenic diagnosis of neonatal sepsis .

目的：探讨静脉滴注免疫球蛋白（IVIG）治疗新生儿败血症的临床效果。

Objective : To investigate the effect of large dosage of IVIG in treatment of neonatal hematosepsis .

结论IL-6、CRP可作为早期诊断新生儿败血症的指标，对制定治疗方案，改善预后具有重要的参考意义。

Conclusion Serum IL-6 and CRP might be looked as an early indicator for neonatal sepsis and have significance of making therapeutic schemes and improving prognosis .

结论：PCT对新生儿败血症早期诊断具有一定的参考价值。

CONCLUSIONS : PCT is a promising marker for the early diagnose of bacterial sepsis in critically ill neonates .

结果新生儿败血症患儿血清FT3水平下降，低于对照组；

Results Compared with control group , the level of FT_3 in serum was decreased in neonate septicemia .

目的：探讨耐甲氧西林凝固酶阴性葡萄球菌（MRCNS）在新生儿败血症中的分布、临床特征及耐药性特点。

Objective : To study the distribution and features of drug resistance of MRCNS in neonatal septicemia .

新生儿败血症最常合并呼吸道感染，其次是皮肤粘膜感染与颅内感染，两组之间在消化道、颅内、皮肤和泌尿系的感染率有显著差异（P0.05）。

The most common complication is respiratory tract infections , then skin infections and intracranial infections . There are significant difference in infection rates among GI tract , CNS , skin and urinary system ( P0.05 ) .

目的：评价降钙素原（PCT）对新生儿败血症早期诊断的价值，并与大众已知的细菌感染标志物如C反应蛋白（CRP）等进行比较。

OBJECT : To evaluate procalcitonin ( PCT ) as a diagnostic marker of bacterial sepsis in critically ill neonates and to compare the results of PCT with those of C-reactive protein ( CRP ) .

目的建立16SRRNA基因加基因芯片检测新生儿败血症的诊断技术，以提高临床检测细菌的速度及准确性。

Objective To improve the speed and accuracy of bacteria detection , and develop the test of 16S rRNA genes PCR amplification plus gene chip hybridization to diagnose neonatal sepsis .

NEC是导致新生儿败血症死亡的重要原因，重视和预防新生儿败血症并发症的发生，特别是NEC的发生。

NEC is an important cause of death in neonatal sepsis , neonatal sepsis and complications , especially the occurrence of NEC should be valued . 3 .

【目的】探讨白细胞介素6（IL6）在新生儿败血症及败血症休克中的变化及临床意义。

Objective To investigate the clinic value of interleukin 6 ( IL 6 ) in sepsis and septic shock .

方法：采用半定量固相免疫测定法测定108例新生儿败血症（40例合并败血症休克）的血浆PCT水平，并比较同期CRP和IL-6水平。

Methods : Plasma PCT levels of 108 neonates with sepsis ( 40 with septic shock ) were measured by semi-quantitative solid phase immunoassay . At the same time , the plasma CRP and IL-6 levels were observed .

对于早产儿和低出生体重儿出现反应欠佳、腹胀或喂养不耐受时要警惕晚发型败血症的发生.2.新生儿败血症常见的并发症按发生频次：化脓性脑膜炎、NEC、MOF、感染性休克和DIC。

For preterm children and low birth weight children who appear poor response , bloating or feeding intolerance should think highly of late-onset sepsis . 2 . The common complication of neonatal sepsis include by frequency of occurrence : purulent meningitis , NEC , MOF , septic shock and DIC .

结论新生儿败血症及败血症休克早期血清IL6水平升高、IL6mRNA表达增强，与病情、预后有关，早期检测意义较大。

Conclusion Increased IL-6 mRNA expression and serum IL-6 levels in the early stage of neonatal sepsis and septic shock are associated with the severity and outcome of illness . Determination of IL-6 levels seems to be an early indicator of neonatal bacterial infection .

头孢噻肟钠治疗新生儿败血症86例临床分析

Clinical Analysis of Cefotaxime Sodium Treating 86 Cases of Neonatal Septicemia

新生儿败血症休克血浆内皮素水平的研究

Studies on the Plasma Endothelin in Newborn Babies with Septic Shock