致病岛

cag致病岛缺失的中国幽门螺杆菌突变菌株的构建及鉴定

Construction and analyses of mutant Chinese H.pylori strains deleting cag pathogenicity island

cag致病岛在中国人感染幽门螺杆菌中的结构特征及分类价值

The characteristic structure and classification of cag pathogenicity island in Chinese Helicobacter pylori strains

幽门螺杆菌cag致病岛基因与胃部相关疾病关系的研究

Study of relation between cag pathogenicity island genes of Helicobacter pylori and gastric associated diseases

幽门螺杆菌感染者中cag致病岛的分布及其意义

The distribution and significance of cag pathogenicity island of Helicobacter pylori isolated from Chinese patients

目的探讨cag致病岛的左右两部分cagⅠ与cagⅡ在中国人群感染幽门螺杆菌（Hp）中的分布差异及其与Hp致病的相关性。

Objective To investigate the difference of cag ⅰ and cag ⅱ in distribution of Helicobacter pylori ( Hp ) isolated from Chinese patients , and its relationship to gastroduodenal diseases .

上海地区幽门螺杆菌菌株cag致病岛基因cagA、cagE、cagT检出率及临床意义

Prevalence of cagA , cagE and cagT genes in cag pathogenicity island of Helicobacter pylori strains isolated from Shanghai patients and their clinical implications

目的探讨cag致病岛基因群的右半部分cagI中cagA与cagM在中国人群感染幽门螺杆菌（H.pylori）中存在的差异及意义。

AIM To investigate the existing difference between cagA and cagM in cag ⅰ of Helicobacter pylori ( H. pylori ) isolated from Chinese patients .

方法针对已知cagA基因两侧及cag致病岛右侧反转重复序列设计PCR引物，扩增cagA基因并克隆测序，分析已知cagA序列同源性及其酪氨酸磷酸化位点。

Methods PCR primers designed according to the nucleotide acid sequence flanking the open reading frame of cagA and the lower reverse repeat sequence of cag pathological island were used to amplify cagA genes of H. pylori strains .

目的分析临床分离的幽门螺杆菌的cag致病岛的差异和不同激酶抑制剂对幽门螺杆菌诱导人胃上皮细胞白细胞介素8（IL8）分泌的影响。

Objective To study the effect of different cag pathogenicity island in Helicobacter pylori ( Hp ) from Chinese patients and various kinase inhibitors on Hp induced interleukin 8 ( IL 8 ) secretion in Chinese gastric epithelial cells .

目的检测上海地区幽门螺杆菌（Hp）分离株cag致病岛（PAI）中cagA、cagE、cagT基因，初步探讨cagPAI的完整性及其与胃十二指肠疾病的关系。

Objective To investigate the prevalence of the cagA , cagE and cagT , representative genes of cag pathogenicity island ( PAI ) in H. pylori strains isolated from patients with various gastroduodenal diseases in Shanghai and the relationship between the presence of these genes and gastroduodenal diseases .

幽门螺杆菌致病岛与临床胃肠疾患的相关性研究

Correlativity analysis between cag pathogenicity island of Helicobacter pylori and gastric diseases

病原微生物致病岛的研究

The study on pathogenicity islands of pathogens

致病岛及其分泌系统

Pathogenicity Islands and Secretion System

为进一步研究大肠杆菌高致病性毒力岛（HPI）的致病机理及免疫机理打下了重要基础。

It lays an important foundation for further study of pathogenic mechanisms and immune mechanism of E.coli pathogenicity island ( HPI ) .

沙门氏菌的致病性主要由鞭毛，菌毛和沙门氏菌致病岛基因决定。

The virulence of Salmonella is determined by flagella , fimbriae , and Salmonella pathogenicity islands ( SPI ) genes .