内毒素移位
- 网络endotoxin translocation;bacterial translocation
-
目的:观察血小板激活因子拮抗剂对急性重症胰腺炎(SAP)时肠粘膜损伤以及细菌和内毒素移位的影响。
Objectives : To study the roles of platelet activating factor ( PAF ) in the pathogenesis of intestinal mucosal injury and endotoxin / bacterial translocation in severe acute pancreatitis ( SAP ) in pigs .
-
重症急性胰腺炎患者因肠道粘膜屏障功能受损,细菌与内毒素移位,导致严重感染发生和多器官功能损害,对疾病恶化起重要作用。
The injured gut barrier and the bacterial translocation in the patients of sever acute pancreatitis could lead to serious infections as well as multiple organ failure , which play an important role in the aggravation of the disease .
-
结论肠道IR损伤可引起小肠、盲结肠的细菌内毒素移位
Conclusion Intestinal ischemia reperfusion can induce bacteria endotoxin translocation from the ileum and cecum . Blind Shaft
-
中药大腹皮抑制肠道内毒素移位中iNOS、SP的作用
Inhibitory role of iNOS and SP in intestinal endotoxin translocation induced by pericarpium arecae in rats
-
结论SAP早期即有细胞因子水平的升高和肠道屏障的损害,细胞因子通过损害肠道屏障,引起肠源性细菌和内毒素移位;
Cytokines may impaired the intestinal microcirculation leading to gut barrier damage , which could promote the intestinal bacteria-endotoxin translocation .
-
目的观察急性坏死性胰腺炎(ANP)时肠粘膜屏障的改变和肠源性细菌和内毒素移位。
Objective To observe the changes in gut mucosal barrier and gut-origin bacteria-endotoxin translocation in acute necrotizing pancreatitis ( ANP ) rats .
-
目的:探讨创伤休克对内毒素移位的影响及其与TNF、IL-6产生的关系。
Objective : To investigate the effect of traumatic shock on endotoxin translocation and its relationship with tumor necrosis factor ( TNF ) and interleukin 6 ( IL 6 ) production .
-
结论丹参能有效防治烫伤后内毒素移位,其作用机制可能与影响肠组织内ET、NO含量,调节ET/NO比值进而改善肠黏膜血液循环有关。
Conclusion Salvia can prevent the LPS translocation in scalded rats effectively by changing ET and NO , and modulating ET / NO so as to the improvement of the microcirculation .
-
结论:AP中早期肠内营养能很好耐受,EN可维持正常肠结构从而减少细菌及内毒素移位,并可维持宿主的免疫应答功能。
Conclusion : Jejunal administration of EN is well tolerated in early AP , maintains immune responsiveness and gut integrity , and reduces bacterial and / or endotoxin translocation .
-
PCR阳性与血浆D一乳酸、LPS升高具有良好的相关性,提示肠屏障损害所致的肠通透性升高导致了细菌和内毒素移位;
The good correlation among PCR positive results and elevated plasma levels of D-lactate and LPS indicated that increased intestinal permeability , caused by gut barrer function damage , led to bacterial and endotoxin translocation .
-
目的:观察磷脂酶A2抑制剂氯喹(CQ)对全肝缺血再灌注大鼠肠上皮细胞凋亡及肠道细菌/内毒素移位的影响。
Objective To observe the effect of chloroquine on the apoptosis of intestinal mucosa epithelial cell and enterogenous bacteria-endotoxin translocation after total hepatic ischemia-reperfusion in rats .
-
目的观察烫伤后肠源性内毒素移位与肝组织内毒素增敏系统&脂多糖结合蛋白/脂多糖受体CD14(LBP/CD14)的相互关系及其意义。
Objective To explore the significance and the correlation between enteric endotoxin translocation and hepatic endotoxin-sensitivity-enhancing system ─ lipopolysaccharide-binding protein ( LBP ) / lipopolysaccharide receptor CD14 ( LBP / CD14 ) after burn .
-
目的观察人重组生长激素(rhGH)对肠道缺血再灌注(IIR)损伤后肠源性细菌/内毒素移位的影响。
Objective To observe the effects of recombinant human growth hormone ( rhGH ) on enterogenous bacteria endotoxin translocation ( EBET ) after intestinal ischemia reperfusion injury ( IIR ) in rats .
-
肠道选择性抑菌(SDD)对内毒素移位的抑制作用不明显,不能有效地抑制MODS的发生及降低死亡率;
SDD group had a higher incidence of the MODS and mortality than that of the EN group . Conclusion : Ischemia-reperfusion damage can produce the LPS translocation , which causes the development of MODS .
-
目的:探讨饥饿后大鼠肠黏膜形态学结构的变化规律,并动态观察GLN肠内补充对饥饿大鼠内毒素移位和肠黏膜免疫功能的影响。
AIM : To investigate the changes in intestinal structure and function as well as the effect of enteral glutamine ( GLN ) supplement on the endotoxin translocation and immunological function in starved rats .
-
以FITC-LPS为示踪物对小鼠肠道内毒素移位的观察
Method of Observation on Phenomenon of Translocation of LPS from Gut with FITC LPS as Tracer in Mice
-
结论:应用外源性GLP-2能减轻严重烧伤后肠黏膜损伤,保护肠黏膜屏障功能,对严重烧伤后肠道细菌/内毒素移位有一定的防治作用。
CONCLUSIONS : Exogenous GLP-2 attenuates intestinal mucosa damage and protects intestinal barrier function , which may be beneficial to the prevention and treatment of bacterial or endotoxin translocation in severe burns .
-
结论严重烫伤后EEN可维护肠道结构和功能,减少细菌和内毒素移位,从而减轻机体的炎症反应;EEN+rhGH的作用优于单纯EEN。
Conclusion Early enternal nutrition could maintain the structure and function of intestine in severely scalded rats , prevent the bacterial and endotoxin from translocating , and alleviate the hypermetabolism reaction , and the effect of EEN + rhGH was better than that of EEN .
-
丙泊酚对大鼠肠缺血内毒素移位及肺损伤的影响
Effects of propofol on intestinal ischemia - reperfusion injury in rats
-
双歧杆菌对动物肠道细菌和内毒素移位的影响
Effects of Bifidobacterium on translocation of bacteria and endotoxin in animal intestine
-
肠道双歧杆菌与烫伤大鼠肠源性细菌/内毒素移位
The relationship between intestinal bifidobacteria and bacteria / endotoxin translocation in scalded rats
-
减少肠道内毒素移位,调理枯否细胞活化;
Lessening the gut translocation of endotoxin , modulating activity of Kupffer 's cell ;
-
结论多发伤后出现肠道通透性增高,肠黏膜完整性受损,有细菌、内毒素移位发生。
Conclusion Bacterial and endotoxin translocation emerged with increasing gut permeability after multiple firearm injuries .
-
谷氨酰胺对饥饿大鼠内毒素移位和肠黏膜免疫功能的影响
Effects of enteral glutamine supplement on endotoxin translocation and mucosal immune barrier in starved rats
-
生长激素减轻梗阻性黄疸时肠菌及内毒素移位的实验研究
Effect of Recombinant Human Growth Hormone on Intestinal Bacteria and Endotoxemia Translocation in Experimental Obstructive Jaundice
-
烫伤大鼠肠内毒素移位对淋巴细胞凋亡的影响
The effects of gut - origin lipopolysaccharide translocation on the apoptosis of lymphocytes in scalded rats
-
结论研究表明恶性肿瘤和放疗化疗导致肠粘膜屏障受损,肠粘膜通透性增加导致内毒素移位。
Conclusions Our study implied that malignant tumor , radiotherapy / chemotherapy might impair gut mucosal barrier .
-
肠淋巴途径在失血性休克大鼠肠源性细菌/内毒素移位发病学中的作用
Role of intestinal lymphatic pathway in pathogenesis of intestine-derived bacteria / endotoxin translocation in rats in shock
-
选择性肠道去污和盲肠造口/结肠灌洗对猪急性重症胰腺炎后肠源性细菌/内毒素移位的影响
Influence of SDD and caecostomy / colonic irrigation on gut endotoxin / bacteria translocation following acute severe pancreatitis
-
人重组生长激素对大鼠肠道缺血/再灌注损伤后肠源性细菌/内毒素移位的影响
Effects of recombinant human growth hormone on enterogenous bacteria endotoxin translocation after intestinal ischemia reperfusion injury in rats