全身给药

方法通过ET和EP两个联合化学治疗方案每21～28天周期全身给药的方法，共收治晚期非小细胞肺癌65例，其中腺癌42例，鳞癌21例，其他2例。

Methods Through every 21 to 28 days cycle , systemic administration of ET and EP combination chemotherapeutic regimen , a total of 65 cases of advanced stage non-small-cell lung cancer were enrolled . Among them , 42 cases were adenocarcinoma , 21 spuamous cell carcinoma and 2 others .

在大鼠甩尾试验中，REC62.5mg/kg（相当于全身给药的1/160，i.c.v.）

In the rat-tail flick assay , the administration of REC at 62.5 μ g / kg ( 1 / 160 of systemic dose ; i.c.v. )

牙根管全身给药假说

Hypothesis on delivering medicine to the whole body through the root canal

鼻腔作为全身给药途径的研究

Study on nasal cavity as drug systemic administration route

结果脉络膜上腔给药组抑制炎症和增殖反应的效果优于全身给药组。

Results The effect of suprachoroidal space administration was superior to that of muscle injection .

目的比较脉络膜上腔给药与全身给药治疗眼穿通伤的疗效。

Aim To compare the therapeutic effects of suprachoroidal space drug administration and muscle injection on perforating ocular injury .

口服给药是全身给药的最简单便捷的给药途径，人们尝试了很多方法来制备口服缓控释制剂，以达到提高药物生物利用度，减少给药次数的目的。

Oral ingestion is the predominant and most preferable route for drug delivery . People have tried a lot to develop oral sustained-release preparation in order to improve the bioavailability and decrease administration times .

许多抗细胞增殖药物虽在动物实验中取得了较好的效果，但在临床实践中却没有达到预期的疗效，一个重要的原因是全身给药很难在病变血管局部达到持续有效的药物浓度。

Although many anti-proliferation drugs have good effects in animal experiments the clinical uses of them have depressed us . An important reason is that they could not reach the sufficient concentration at local vascular vessel by systemic therapy .

γδT细胞制品安全性研究主要包括急性毒性、过敏性、溶血性和局部刺激性等主要的、局部的、全身给药相关的特殊安全性实验及致瘤性检测。

Safety investigation of γδ T cells preparation . The safety test mainly included tumorigenicity test , systemic and local safety tests such as acute toxicity , allergy , hemolytic and local irritation which were related to local or systemic administration .

目的：探讨立止血局部和全身同时给药治疗新生儿急性胃粘膜出血的疗效。

Objective : Probe into the curative effect of part or whole reptilase in the treating neonatal acute gastric mucosal hemorrhage .

我院治疗方式包括单独或联合应用甲氨蝶呤（methotrexate，MTX）全身或局部给药、子宫动脉栓塞术、介入化疗、腹腔镜下病灶切除术、开腹子宫病灶切除术、清宫术等。

The methods of treatment in our hospital included systemic or local methotrexate administration , uterine artery embolization , interventional chemotherapy , hysteroscopy and lesion excision , laparotomy and curettage .

结论瘤内注射5-Fu-NPs缓释剂的抗肿瘤效果优于局部和全身单纯5-Fu给药，它具有较重要研发价值。

Conclusion The antitumor effect of intratumoral administration of 5-fluorouracil-loaded polyactic acid is better than that of local and systemic administration of 5-Fu alone .

卵巢癌免疫治疗可分为预防性和治疗性免疫两种，同时还可分为腹腔内与全身两种给药方式。

Immunotherapy for ovarian cancer involve prophylactic and therapeutic approaches , as well as locoregegional and systemic therapies .

支气管动脉灌注化疗（BAI）与全身化疗不同在于给药方式的不同导致的药物代谢动力学的不同。

Bronchial Artery Infusion Chemotherapy ( BAI ) differs from systemic chemotherapy in the way that drugs are administrated , which results in distinct pharmacokinetics .

用于全身治疗的鼻腔给药系统研究概况

The General Investigation of Nasal Drug Delivery System for Systemic Therapy