重型肝炎

慢性重型肝炎患者乙肝病毒C基因变异的初步研究

A preliminary study of hepatitis B virus core gene mutations in chronic severe hepatitis

结论：PE为重型肝炎提供了有效，安全的治疗手段。

Conclusions : PE is an effective and safe method to treat method the severe hepatitis .

HBV－DNA前C区变异的重型肝炎末梢血T细胞亚群分布的研究

Study of the Peripheral Blood T Lymphocyte Subtype in Fulminant Hepatitis with Mutant and Non-mutant on HBV pre-C Region

慢性乙型重型肝炎HBV基因型和核苷酸多态性分析

Genotypes and nucleotide polymorphisms in patients with severe chronic hepatitis B in Wuxi region

前列腺素E1对慢性重型肝炎患者血清可溶性白细胞介素-6受体及其β链的影响

Effect of prostaglandin e_1 on sIL-6R and its β strands in serum in patients with chronic severe hepatitis

目的探讨血浆置换术（PE）治疗各型重型肝炎的疗效及影响疗效的相关因素。

Objective To discuss the efficacy and its influence factors of the treatment with plasma exchange .

结论重型肝炎中，变异株HBV感染率很高；

Conclusion In fulminant hepatitis , the infective rate of HBV mutate type is high .

结论IL-10启动子区基因多态性与HBV感染所致肝病的肝损害进展和重型肝炎的发生可能有关。

Conclusion IL-10 gene polymorphism was associated with the chronic severe hepatitis .

重型肝炎单核细胞培养上清和血浆TNFα含量的检测

A Survey of the Monocyte Cultural Supernatant and the Plasma TNF α Content of Severe Hepatitis

比较各型肝炎的凋亡细胞密度发现，重型肝炎的凋亡细胞密度高于慢性肝炎和肝硬变（P均<0.01）；

The density of the apoptotic cells in severe viral hepatitis was significantly higher than that in chronic hepatitis and liver cirrhosis ( both P < 0 . 01 ) .

结论：南通地区HBV基因型以B、C型为主，C型为优势基因型，并与重型肝炎、肝硬化、肝癌的发生及血清HBV-DNA高载量相关。

Conclusions : The dominant genotype of HBV in Nantong is genotype C ; Genotype C is associated with the development of severe liver diseases .

目的探讨无锡地区慢性乙型重型肝炎HBV基因型和核苷酸多态性分布的特点。

Objective To explore the features of genotypes and nucleotide polymorphisms in the patients with severe chronic hepatitis B in Wuxi region .

目的观察慢性肝炎、重型肝炎患者血清脂多糖结合蛋白（LipopolysaccharideBindingProtein，LBP）的变化。

Objective To observe the variability of lipopolysaccharide binding protein ( LBP ) in patients with chronic hepatitis and severe hepatitis .

目的应用终末期肝病模型（modelforend-stageLiverDisease，MELD）评分系统预测血浆置换治疗后重型肝炎患者的预后。

Objective To study prognosis of patients with fulminant hepatitis after plasma exchange treatment using MELD ( model for end-stage liver disease , MELD ) scoring system .

揭示慢性病毒性乙型重型肝炎（简称乙型慢重肝）舌质、舌苔R、G、B值的客观特征。

To reveal the objective characteristic of body of the tongue , tongue fur and the R , G , B value in chronic severe viral hepatitis B ( CSHB ) .

根据PTA预测血浆置换治疗重型肝炎高胆红素血症的疗效

Assessment on curative effect of plasma exchange for treating chronic severe hepatitis with hyperbilirubinemia based on prothrombin activity

结论在FFP供应不足的情况下，24h内制备的FP可以代替FFP进行血浆置换治疗慢性重型肝炎。

Conclusion FP can replace FFP to treat chronic severe hepatitis with plasma exchange .

HGV感染可能与一些急性重型肝炎发病有关。

Our results support that HGV infection is associated with some Acute fulminant hepatitis .

结果表明，HBV感染家庭集聚者肝癌、肝硬化、重型肝炎的发生率和病死率极高。

The results showed tha the incidences of hepatoma , cirrhosis and severe hepatitis were very high in the member of the home with HBV aggregative infection .

血液淋巴细胞计数、HBV-DNA载量、血清总胆固醇对重型肝炎诊断及预后判断的价值

Diagnostic and Prognostic Value of Blood Lymphocyte Count , HBV-DNA Load , and Serum Total Cholesterol in Severe Hepatitis

IL-4对重型肝炎患者外周血单个核细胞IL-1α表达调节的研究

Study on regulation of IL 4 on expression of IL 1 α in PBMCs from patients with subacute and chronic severe hepatitis

用MELD预后分析甘利欣治疗慢性重型肝炎的疗效

The efficacy of diammonium glycyrrhizinate injection on chronic severe hepatitis evaluated by MELD analysis

ALSS治疗可显著升高慢性重型肝炎ChE值，并提高好转率。血清ChE可作为ALSS治疗后的预后判断指标之一。

ChE of chronic severe hepatitis and improvement rate significantly increased after treatment of ALSS .

HGV感染在肝炎各临床类型分布为急性、慢性和重型肝炎患者无明显差异，且无性别和年龄分布的差异。

HGV infecting rate showed no difference concerning clinical type of hepatitis as well as sex and age .

结果经临床观察、对照和分析，发现重叠HEV感染的慢性乙肝患者的重型肝炎发生率和慢性乙肝重度发生率高。

Results When chronic hepatitis B patients were superinfected by HEV , the incidence rate of hepatitis gravis and severe hepatitis was higher .

目的评估终末期肝病模型（modelforend-stageLiverDisease，MELD）评分系统对慢性重型肝炎患者短期（3个月）预后的预测能力及临床应用价值。

Objective To study the clinical practical use of the model for end-stage liver disease ( MELD ) and assess its validity in predicting the prognosis of the . chronic severe hepatitis patients .

应用此型BAL对乙型重型肝炎患者稀释血清进行3h的体外灌流实验。

Diluted serum samples of severe hepatitis B were circulated for 3 hours in the extracorporeal circulatory system including the BAL .

结果7例亚急性重型肝炎病人的HBV分离株CP区分别有2～12个替代变异，1例病人有11bp的碱基插入。

Results There were 2 12 nucleotide substitutions in CP region in the 7 subacute fulminant hepatitis patients studied . An 11 bp nucleotides insertion was found in one patient .

目的应用分子吸附循环系统（MARS）治疗慢性重型肝炎并多脏器衰竭（MOF）患者，观察其在肝脏支持及治疗由肝功能衰竭引起多脏器衰竭的临床效果。

Objectives To evaluate the therapeutic effects of molecular adsorbents recirculating system ( MARS ) on chronic severe hepatitis patients complicated with multi-organ failure .

结论：lipoPGE1辅助治疗慢性乙型重型肝炎有良好疗效。

CONCLUSION : Lipo PGE 1 has a good therapeutic effect on chronic severe type B hepatitis .