表面受体
- 网络Surface receptor;cell surface receptor;TCR
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用肝素释放细胞表面受体结合的LDL并比较兔及人血清LDL结合能力
Release of LDL from cell surface receptor by heparin and comparison of the binding ability of serum LDL between rabbit and man
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整联蛋白是一类主要的将细胞黏附到ECM的细胞表面受体,通过细胞骨架组织细胞形状,它们也影响细胞命运的决定。
Integrin is a major cell surface receptor adhering cell to ECM , cell shape was organized by cytoskeleton , they also affect cell fate decisions .
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Fas,FasL均是细胞表面受体。
Fas and FasL are both surface receptors on cells .
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G蛋白偶联受体(GPCR)是另一类重要的细胞膜表面受体超家族。
G protein-coupled receptors ( GPCRs ) constitute another superfamily of plasma membrane receptors .
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转化生长因子β(transforminggrowthfactor-,βTGF-β)可通过特异性结合并激活具有丝氨酸/苏氨酸激酶活性的细胞表面受体启动各种应答。
Transforming growth factor β( TGF - β) initiates its diverse cellular responses by binding to and activating specific cell surface receptors that have intrinsic serine / threonine kinase activity .
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急性白血病患者非血缘脐血干细胞移植后NK细胞及其表面受体的早期重建
Reconstitution of NK Cells and Their Receptors in Patients with Acute Leukemia Following Unrelated Cord Blood Stem Cell Transplantation
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脑胶质瘤在其侵袭性生长过程中涉及到多个步骤:肿瘤细胞通过细胞膜表面受体粘附到细胞外基质(Extracellularmatrix,ECM)层粘蛋白上;
Many procedures are involved in the process of invasion of brain gliomas . Tumor cells adhere to extracellular matrix through the membrane receptor .
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LPS刺激牙龈成纤维细胞IL-6、IL-8的产生和膜表面受体CD(14)的表达
Production of IL-6 and IL-8 and expression of CD_ ( 14 ) in cultured human gingival fibroblasts under the action of lipopolysaccharide
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伴随着遗传变异,小细胞肺癌还表现出细胞表面受体的过度表达,包括受体酪氨酸激酶、G蛋白耦合受体、整合蛋白及其它受体等。
Along with the genetic alterations , SCLC overexpresses various cell surface receptors , such as receptor tyrosine kinase ( RTKs ), G-protein-coupled receptors , integrins , and so on .
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结论:青石棉可激活BEAS-2B细胞膜表面受体EGFR的磷酸化。
Conclusion : EGFR phosphorylation could be induced by crocidolite in BEAS-2B cells .
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GP受体的基因突变必然影响血小板表面受体的表达数量与质量,从而影响血小板聚集。
The gene mutations of GP receptors inevitably influence the expression of quantity and quality in platelet surface receptors , and thus affect platelet aggregation .
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RV入侵宿主细胞是一个有机的多步骤过程,有多种受体参与,其作用机理还不完全清楚,目前认为,病毒与宿主细胞表面受体之间至少存在4种相互作用关系。
Rotavirus cell entry appears to be an organized multistep process during which at least four interactions between the virus and cell surface molecules occur .
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HCMV病毒感染细胞的过程是从病毒包膜糖蛋白与靶细胞膜表面受体结合开始的,结合后HCMV以膜融合或受体介导的内吞机制进入细胞。
HCMV infection starts from the viral envelope glycoprotein binding with the cell surface receptor . Then HCMV enters cells by membrane fusion or receptor-mediated endocytosis .
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Erns和E2与细胞表面受体的相互作用介导病毒对细胞的感染过程。
Infection of cells by CSFV is mediated by the interaction of E2 and Erns with cell surface receptor .
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PAR-2是tryptase的细胞表面受体,被tryptase酶切裂解后可介导跨膜信号转导,将细胞外的信号传递到细胞内。
PAR-2 is the cell surface receptors of tryptase , activated by tryptase and then mediating transmembrane signal transduction .
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本组结果说明Fn、Bm在诱导单核细胞释放细胞因子的作用机理与Ec相同,依赖单核细胞膜表面受体CD14。
The results indicated that Fn and Bm share the same mechanism as Ec in the induction of cytokines , which depends on the surface receptor CD14 of monocytes .
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ChristopherGarcia领衔的科研小组揭示了T细胞表面受体结构为何能双重识别,该现象也称为同种异体反应性。
Christopher Garcia have established how the structure of receptors on the surface of T cells enables this dual recognition , a phenomenon known as alloreactivity .
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方法用生物素将体外制备的糖基化终产物(AGEs-BSA)标记成配基,以细胞化学法显示细胞表面受体高亲和性结合。
Methods AGEs-BSA prepared in vitro was labeled with biotin to demonstrate binding of AGEs to receptor for AGEs ( RAGE ) . High affinity binding of cell surface was shown with cell chemistry method .
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野花生豆(Crotalariamucronata)凝集素的细胞表面受体的研究
Study on cell surface receptor of the Crotalaria mucronata lectin
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尿毒症患者NK1细胞表面受体KIR基因的表达
The frequencies and polymorphism of KIRs gene on the surface of NK cells in uremia patients
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TSP-1作为一种重要的细胞外基质糖蛋白通过与其相应的细胞表面受体结合,激活多种信号传导途径从而发挥多种生物学功能。
As an important matricellular glycoprotein , TSP-1 activates many signal transduction pathways to achieve its biological functions by binding to various cell surface receptors .
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本文首次把ABC法应用于受体流动性测量中的膜表面受体荧光标记,利用FRAP(FluorescenceRecoveryAfterPhotobleaching)技术实现了细胞内吞过程中膜受体流动性变化的测量。
In this paper , we carried out the measurement of receptor mobility during endo cyto-sis with ABC ( Avidin-Biotin Complex ) method labeling receptors for the first time by FRAP ( Fluorescence Recovery After Photobleaching ) technique .
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但由于至今未能确定PF4的特异性细胞表面受体,PF4在动脉粥样硬化中的具体作用机制还不十分清楚。
However , no specific cell surface receptor has been found until now , and the specific mechanism in which PF4 affects atherosclerosis is still not very clear .
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结论:患者外周血中CD4+T细胞表面受体的vβ部分可能存在缺陷。
Conclusion : The immune response of patients with oral and maxillofacial malignant tumors is lower than that of the healthy . There may be some defects on the v β chain of TCR on CD4 + T cell in peripheral blood of these patients .
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在注射入人体后,该抗体有望阻止病毒与宿主细胞表面受体ACE2结合。
After being injected into the human body , it 's hoped the antibody will block the virus from binding to the host-cell surface receptor ACE2 .
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RVG是病毒与宿主细胞结合的配体,能与细胞表面受体互作,介导病毒与靶细胞的结合。
RVG is a ligand between the viral and host cell binding , to interaction with cell surface receptors , mediate the combination of virus and target cells .
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虽然这些巨噬细胞亚群的分化和功能已经研究清楚,但是对于决定巨噬细胞极化事件的因素中除了可溶性的细胞因子(例如IFN-γ或者IL-4)之外的细胞表面受体的作用知之甚少。
Although the differentiation and function of these macrophage subsets has been well studied , little is known about the contribution to these differentiation events of cell surface receptors other than those for soluble cytokines , such as IFN-y or IL-4 .
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αMSH通过与其黑素细胞表面受体&黑皮素1受体(melanocortin1receptor,MC1R)结合,使黑素细胞内酪氨酸酶的表达增加、活性增强,黑素合成增加并优先刺激优黑素细胞的合成;
Alpha-msh enhances activity and quantity of tyrosinase as well as stimulates melanogenesis , specifically to stimulate eumelanin synthesis by activating the melanocortin-1 receptor ( MC-1R ) on melanocytes .
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结论:低浓度MNNG对PKA的激活和诱导细胞表面受体聚集均不依赖于基因组DNA的损伤,表明细胞信号转导通路的起源可能位于细胞膜或者细胞质中。
Conclusion : The results indicate that the initiation of signal cascades induced by low concentration of MNNG might be associated with its interaction with cell surface receptors and / or direct activation of related signal proteins but not its DNA damage .
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血清RBP通过与视黄醇、前白蛋白及细胞表面受体相互作用,在VitA的储存、代谢、转运到周围靶器官中具有重要功能;
Under the interaction with substances such as retinol , pre-albumin and the receptors of cellular surface , they play important roles in storage , metabolism of VitA and transport of VitA to the target cells .