两亲性聚合物

聚合物胶束是一种新型的给药系统，由两亲性聚合物在选择性溶剂中自组装形成。

Polymer micelle is a novel drug delivery system , formed from amphiphilic polymer by self-assembling .

两亲性聚合物兼具高分子的增粘性和低分子的表面活性，具有很多独特的物理化学性质。

Because of the specialty of its molecular structure , the amphiphilic polymer has a lot of characteristics .

结果表明通过RAFT活性可控聚合手段得到两亲性聚合物分子具有很好的自组装行为，能够自组装成粒径200nm左右的具有核-壳结构、结构规整的球状颗粒。最大物质包裹效率达到58.8%。

The results show that the amphiphilic polymers have good self-assembly behavior whose particle size is about 200 nm , and Maximum package efficiency of 58.8 % .

结果表明，该两亲性聚合物载体拥有很高的药物运载能力，还可以和DOX一起协同治疗，表现了良好的协同作用。

The results show that the functional polymer is not only has a high drug loading capacity , but also can combine with the anti-cancer treatment of DOX .

众所周知，在高分子科学领域研究的一个重要概念就是聚合物结构决定性能，因此设计合成具有精确结构的含POSS两亲性聚合物是深入的研究其相关性能的前提和基础。

It is well known that material properties depending on its molecular structure are the basic principle in the field of polymer science . Therefore , the design and synthesis of well defined amphiphilic POSS containing polymers are the precondition and foundation of its related properties and applications .

国内减水剂用两亲性聚合物的研究进展

Studies progress of amphipathic polymer for water reducing agent in China

环氧乙烷与苯乙烯两亲性聚合物的合成苯乙烯-二元乙丙橡胶嵌段共聚物增韧聚丙烯

Toughening of polypropylene by styrene - ethylene propylene diblock copolymer

几乎所有疏水性无机纳米粒子可以与这些两亲性聚合物涂层。

Virtually all hydrophobic inorganic NPs could be coated with these amphiphilic polymers .

两亲性聚合物改性二氧化硅及其与聚丙烯酸酯乳液复合体系性能研究

Silicas Modified with Amphibious Polymers and Properties of Their Composites Formed with Polyacrylate Emulsion

这种高生物相容性和刺激响应型的两亲性聚合物胶束在抗癌药物载体方面具有潜在的应用前景。

The high biocompatibility and responsive amphiphilic polymer micelles would have potential applications in the anti-cancer drug carrier .

含聚乙二醇两亲性聚合物及其胶束用作药物载体的理论研究及应用潜力

Theoretical research and application potential of amphiphilic polymers containing polyethylene glycol and their micelles used as drug carriers

通过两亲性聚合物结构在水溶液中的自组装，成功制备得到基于该聚合物的杂化纳米粒子。

Hybrid nanoparticles ( NPs ) were then fabricated via the self-assembly of the polymers in aqueous solution .

简述了国内混凝土减水剂用两亲性聚合物主要类型和性能及研究进展。

Main Types and performance of Amphipathic polymer in water reducing agent in Concrete in China were briefly introduced .

近年来，两亲性聚合物分子的自组装及其聚集体由于其潜在的生物科技及医药上的应用而愈来愈受到重视。

In recent years , various polymeric amphiphiles have received increasing attention because of their potential applications in biotechnology and pharmaceutical fields .

两亲性聚合物的疏水嵌段形成了胶束的内核，而亲水部分则形成了胶束的外壳。

The hydrophobic segment of the polymer forms the core of the micelles , whereas the hydrophilic segment forms the corona or outer shell .

两亲性聚合物由亲水性链段和疏水性链段组成，并能在水溶液中自发形成具有核-壳结构的聚合物胶束。

Amphiphilic block copolymers consisting of a hydrophilic and a hydrophobic segment self-assemble into polymeric micelles in aqueous solution with a hydrophobic core stabilized by a hydrophilic shell .

为了实现这个目标，人们设计出了多种药物输送载体结构，其中在药物释放体系中研究最广泛的两亲性聚合物包括两嵌段和三嵌段共聚物。

To this goal , different types of drug carriers have been designed . The most widely studied amphiphilic polymers for drug delivery include diblock copolymers and triblock copolymers .

两亲性聚合物为既有亲水链段又有亲油链段的聚合物。近年来，两亲性共聚物在诸多方面表现出的特性引起了人们的关注。

For showing features in many fields , the amphiphilic copolymer containing hydrophilic segment and oleophilic segment in the same molecular chain have attracted more and more attention in recent years .

由于两亲性聚合物特殊的生物性能及可控合成。近年来，对其应用领域的研究越来越多。

In recent years , more and more researches have been carried out on the application of amphiphilic polymers due to the special biological properties and controllable conditions of amphiphilic polymer synthesis .

目前，两亲性聚合物的合成及其聚集行为已经得到深入广泛的研究，但是涉及天然高分子及其衍生物胶束行为的报道较少。

Currently , the synthesis of amphiphilic polymers and their aggregation behavior has been studied extensively , but there are a few reports on aggregation behavior based on natural polymer and its derivatives .

由于在药物增溶和延长体内循环时间上具有显著优势，两亲性聚合物自组装胶束在药物传输领域吸引了越来越多的关注。

Polymeric micelles self-assembled from amphiphilic polymers have attracted more and more attention in the field of drug delivery due to their distinct advantages including improved solubility of hydrophobic anticancer drugs and prolonged circulation time .

两亲性嵌段聚合物的同步辐射小角x射线散射研究

Analysis of the aggregation structure from amphiphilic block copolymers in solutions by small-angle x-ray scattering

结合阴离子聚合和活性自由基聚合方法合成了聚环氧乙烷-聚丙烯腈两亲性嵌段聚合物（PEO-b-PAN）。

Amphiphilic block copolymer poly ( ethylene oxide ) - polyacrylonitrile ( PEO-b-PAN ) have been synthesized through the combination of anionic polymerization and atom transfer radical polymerization ( ATRP ) .

壳层悬挂β-环糊精单元的两亲性超支化聚合物的分子包合与识别行为

Molecular Inclusion Complexation and Recognition Behavior of Amphiphilic Hyperbranched Polymer Carrying β - Cyclodextrin as Pendant Groups on Shell Layer

论文对齐聚物、两亲性嵌段聚合物的合成、表征，以及载药胶束的形态尺寸等进行了研究。

The preparation and characterization of oligomers and amphiphilic block copolymers , the morphology and size of drug-loaded micelles were studied .

两亲性嵌段聚合物因其特殊的性能，在医用材料表面改性、药物载体等领域具有潜在的应用价值，已经成为高分子领域的研究热点。

Amphiphilic diblock copolymer has attracted much attention of world-wide scholars in polymer science due to its unique property and potential applications in many fields such as surface modification of medical materials and drug carriers .

研究了两亲性嵌段动态聚合物PS-b-PEG体系在选择性稀溶液中的自组装行为，发现和传统的两亲性嵌段共聚物一样，两亲性嵌段动态聚合物PS-b-PEG体系也能自组装得到多种形貌。

Similar with conventional amphiphilic block copolymers , the amphiphilic dynamic block copolymer systems ( PS-b-PEG ) can be self-assembled into diverse morphologies in dilute selective solvent .

本文主要包括下面两方面的内容：采用“center-linking”方法制备了V型两亲性聚合物官能化纳米硅球并研究了其自组装行为。

This dissertation contains the following aspects : A series of amphiphilic polymer grafted silica nanoparticles have been prepared and the self-assembly of which is studied .