驱动蛋白

前言：目的：揭示1-甲基-4-苯基-1，2，3，6-四氢吡啶（MPTP）对C57BL小鼠黑质与纹状体神经元驱动蛋白超家族（KIF）基因表达的影响。

AIM : To investigated the effect of1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine ( MPTP ) on the expression of kinesin superfamily ( KIF ) genes in striatum and substantia nigra in C57BL mice .

目的探讨大鼠大脑皮质神经元驱动蛋白超家族（KIF）基因在脑发育时期和成年期表达的差异，揭示KIF在脑发育和神经功能维持方面的作用。

Objective To investigate the expression of kinesin superfamily ( KIF ) genes in cerebral cortex of adult and newborn SD rats .

2.18F标记纺锤体驱动蛋白（KSP）抑制剂探针前体的合成。

Synthesis of the precursor of F-labeled kinesin spindle protein ( KSP ) inhibitors .

目的探询脑室定向注射淀粉样蛋白对大鼠大脑皮层神经元驱动蛋白超家族（KIFs）基因表达的影响。

Objective To investigate the effect of amyloid on the expression of kinesin superfamily ( KIFs ) genes in cortex of Wistar rats .

构象耦合模型下驱动蛋白定向运动机制的研究

The Study on the Directional Motion of Kinesin under Coupled Conformational Model

驱动蛋白及其电荷分布的研究

The Study of Kinesin and Its Charge Distribution

中药复方制剂对缺氧大鼠微管蛋白和驱动蛋白表达影响的研究

Effects of Compounded Chinese Medicinal Prescription on Tubulin and Kinesin Gene Expression in Hypoxia Rats

驱动蛋白研究进展

Advances in the Studies of Kinesin

迄今为止，很多驱动蛋白及类驱动蛋白在包括拟南芥在内的植物中被鉴定。

To date , many kinesins or KLPs were identified from Arabidopsis thaliana and other higher plants .

驱动蛋白系统的分为3个家族：N-末端、C-末端和M-末端。

Three classes of kinesin have been systematically identified : N-terminus , C - terminus and M - terminus .

驱动蛋白的运动具有定向运动和梯跳两个特性，这两个特性蕴含的机制一直是人们研究的焦点。

The movements of kinesin have two features , the directionality and the stepping motion , on which the dynamical study are focused .

特别是驱动蛋白马达，它具有定向梯跳的运动特性，其中蕴含的动力学机制已成为众多研究者们关注的焦点。

Particularly , kinesin , which has the feature of directivity and stepping motion , has been focused on its particular dynamical mechanism .

了解驱动蛋白这些令人惊奇的特性及其物理根源，为我们设计性能优越的人工分子马达提供了参考。

The unambiguous physical understanding developed in this thesis of these amazing characteristics of kinesin will be a valuable reference to future development of high-performance artificial molecular motors .

驱动蛋白是一类基于微管组织的马达蛋白家族，这些蛋白沿着微管定向移动并参与许多重要的细胞过程，其中包括植物细胞的伸长。

The kinesins are a family of microtubule-based motor proteins that move directionally along microtubules and are involved in many crucial cellular processes , including cell elongation in plants .

本文内容包括：首先综述生物学领域分子马达研究的最新进展，内容安排为：肌球蛋白的结构和功能，驱动蛋白的结构和功能，肌球蛋白和驱动蛋白定向运动机制的结构生物学方面的最新进展；

The thesis includes three parts : Firstly , previous study and latest advance of molecular motor in biology are outlined , including Myosin 's and Kinesin 's construction and function , the latest advance of molecular motor in constructional biology ;