防己

粉防己碱可明显降低再灌注早期心室颤动的发生（P＜0.05）。

Tet reduced the incidence of ventricular fibrillation significantly ( p < 0.05 ) .

可乐定和汉防己碱抑制高血压大鼠动脉平滑肌DNA合成速率

Inhibition of aortic DNA synthesis by clonidine and tetrandrine in renal hypertensive rats

汉防己甲素预防实验性糖尿病大鼠胰岛B细胞损伤作用的组织学观察

Histology observation of preventive effect of tetrandrine on islet B cells injury in experimental diabetes rats

结论1.以丹参、H七、桃仁、汉防己为主组成的中药制剂能够保护肝功能，对肝纤维化有防治作用。

Chinese herbs can protect hepatic function , and prevent and cure hepatic fibrosis .

汉防己甲素抑制矽肺胶原mRNA表达的研究

Inhibition of mRNA Expression of Silicotic Collagen Gene by Tetrandrine

粉防己碱对烟雾吸入伤家兔炎症细胞合成释放白三烯B4的影响

The effect of tetrandrine on the release of leukotriene b_4 by inflammatory cells of rabbits with smoke inhalation injury

目的用HPLC法对防己药材指纹图谱进行研究。

Objective To study the fingerprint of Radix Stephaniae Tetrandrae by HPLC .

汉防己甲素对气管平滑肌~（45）Ca内流的影响

Effects of tetrandrine on ~ ( 45 ) ca influx in tracheal smooth muscles

粉防己甲素逆转耐药细胞株K（562）/VCR多药耐药的研究

Study on Reversal of Multidrug Resistance of Drug resistance Leukemia K562 / VCR Cells by Tetrandrine

急性毒性实验显示广防己水煎液小鼠LD（50）为69.8305g／kg。

Acute toxic test shows that LD_ ( 50 ) is 69.8305g/kg .

中药粉防己碱对高脂饮食兔脂代谢和主动脉壁血管细胞清道夫受体amRNA表达的影响

Effects of Tetrandrine on Serum Lipid and Expression of Scavenger Receptor-A mRNA in Hypercholesterolaemic Rabbits ' Aorta

汉防己甲素联合柔红霉素对K562/A02细胞株P21蛋白和P糖蛋白表达的影响

Effect of Tetrandrine Combined with Daunorubicin on Expressions of P21 and P-gp in K562 / A02 Cells

结果初步建立了防己药材的HPLC指纹图谱，并进行相似度评价。

Results HPLC Fingerprint of Radix Stephaniae Tetrandra was established and the similarity of the fingerprint was compared .

粉防己碱抑制肝纤维化大鼠肝组织c-fos和c-junmRNA表达

Tetrandrine inhibits expressions of c-fos and c-jun mRNA in fibrotic liver of rats

粉防己碱对肾型高血压左室肥厚大鼠心肌ATP酶活性的影响

Effects of tetrandrine on myocardial ATPase activities in renovascular hypertensive rats with left ventricular hypertrophy

汉防己甲素联合屈洛昔芬对K562细胞bcr/abl表达的影响

Tetrandrine combined with Droloxifene affect the Expression of bcr / abl in K562 cell

蛋白质芯片检测多药耐药蛋白，是以细胞株（K562和K562/A02）、汉防己甲素和屈洛昔芬单独或联合作用的K562/A02耐药细胞及部分临床样品为实验研究对象。

K562 , K562 / A02 and clinic sample were used in the study .

目的探讨汉防己甲素对肾小球硬化大鼠肾脏转化生长因子（TGFβ1）基因表达的影响。

Aim The effect of tetrandrine on TGF - β 1 mRNA expression in glomerulosclerosis rat was observed .

粉防己碱和蝙蝠葛碱对人白血病细胞株HL－60和K（562）的生长抑制作用

Inhibitory effects of tetrandrine and dauricine on growth of HL-60 slid K_ ( 562 ) cell lines

粉防己碱对大鼠角膜新生血管HIF-1α和VEGF表达的影响

Effect of tetrandrine on the expression of HIF-1 α and VEGF in corneal neovascularization of rats

提示抑制NOS活性和NO生成是汉防己甲素防治肝硬化门脉高压症的主要作用机理。

The vitally preventing mechanism of cirrhosis and portal hypertension is inhibiting the enzymatic activity of NOS.

粉防己碱对人宫颈癌Hela细胞增殖与凋亡的影响

Effect of tetrandrine on proliferation and apoptosis of human cervical cancer cell line hela

汉防己甲素对四氧嘧啶致大鼠血清LPO含量及全血GSH&Px活性改变的影响

Effects of tetrandrine on the change of serum LPO level and blood GSH-Px activities induced by alloxan in rats

汉防己甲素干预后的生长抑制曲线一致，无明显差异（P＞0.05）。Tet干预后两种细胞均出现凋亡现象，透射电镜看到凋亡小体。

Their growth suppression curve were coincidence , and apoptotic body being seen in the cells with transmission electron microscope .

结论粉防己碱能增加GSH的神经保护作用。

Conclusion Glutathione combined with tetrandrine could be endowed with the effects of neuroprotective effect .

粉防己碱与BSA相互作用的同步荧光光谱表明，二者的结合对BSA构象产生了影响。

Results of synchronous fluorescence spectrum showed that the binding could cause conformational changes of BSA .

粉防己碱（Tet）对MDCK细胞钙激活钾通道（K（Ca））的影响

Effect of Tetrandrine ( Tet ) on Calcium-Activated Potassium Channels ( K_ ( Ca )) in MDCK cells

粉防己碱逆转耐阿霉素的人乳腺癌MCF-7细胞的抗凋亡作用

Reversal of Anti-Apoptotic Action by Tetrandrine in The Human Breast Carcinoma Doxorubicin Resistant MCF-7 Cells

方法：以风湿镇痛凝胶中汉防己碱为指标，采用Franz小池扩散法。

Methods : Adopting Franz diffusion cell and using tetrandrine as an index .

结论粉防己碱可有效逆转P-gp介导的MDR。

Conclusions : Tetrandrine was effective to overcome P-gp mediated MDR of human bladder cacinoma .