补体调节蛋白

人补体调节蛋白基因MCP和DAF的克隆及其在E.coli中的表达

Cloning and Expression of Human Complement Regulatory Protein Gene MCP and DAF in Escherichia coli

血液透析对转化生长因子β1及补体调节蛋白CD59基因表达的影响

Effects of hemodialysis on the transforming growth factor - β _1 and the expression of complement regulatory protein CD59

它莫西芬对绒毛膜癌细胞株JAR补体调节蛋白表达的影响

Tamoxifen Modulates the Expression of Complement Inhibitory Proteins on Choriocarcinoma Cell Line JAR

变应性鼻炎大鼠鼻黏膜中补体调节蛋白C1-INH和CD46的表达

Expression of complement regulatory proteins C_1-INH and CD46 in nasal mucosa of allergic rhinitis rats

新风胶囊对类风湿性关节炎补体调节蛋白红细胞CR1及CD59的影响

The influence of XinFeng Capsule on complement regulator protein CR1 and CD59 In Patients with Rheumatoid arthritis

与毛细管分离的年轻红细胞相比，年老红细胞表面三种补体调节蛋白数量显著下降，自身抗体IgG敏感性显著增加。

Comparing with the young RBCs obtained by capillary centrifugalization , the quantity of three kinds CRPs of old RBCs decreased remarkably , and the sensibility of auto-antibody IgG increased .

补体调节蛋白CD46、CD55及CD59在肿瘤免疫治疗中的研究进展

Research Progression on Complement Regulatory Proteins CD46 , CD55 , and CD59 in Tumor Immunotherapy

补体调节蛋白CD46对CD4~+T细胞的免疫调控

Immunoregulation of complement regulatory protein CD46 on CD4 ~ + T cells

补体调节蛋白CD46与CD59在胃癌组织及癌旁组织中的表达及其临床意义

The Expression and Clinical Significance of Complement Regulatory Proteins CD46 and CD59 in Human Gastric Cancer and Adjacent Tissues

目的探讨他汀类调脂药物对高脂血症患者外周血白细胞补体调节蛋白CD35表达的影响及在动脉粥样硬化疾病中的作用。

Objective To investigate the effects of atorvastatin on the expression of complement regulatory protein CD35 on leukocytes in hyperlipidemic .

目的研究转人补体调节蛋白（CRP）DAF、MCP和CD59基因对抑制人补体激活从而克服超急性排斥反应的作用。

Objective In order to study the role of human complement regulatory protein ( CRPs ) transgene in including DAF , CD59 and MCP in overcoming hyperacute rejection ( HAR ) .

补体调节蛋白CD46作为一种新的T细胞活化辅助因子可以诱导CD4+T细胞生成IL-10。

Complement regulatory factor CD46 is identified as a physiological costimulatory molecule for T cell activation . It can induce IL-10 production in CD4 + T cells .

它还可以结合补体调节蛋白FH和FHL-1，并可能借此逃避补体攻击、抵抗巨噬细胞的调理吞噬。

It can bind complement regulator protein FH , FHL-1 , which can promote the escape of the complement attack and contribute the anti-phagocytosis .

结论：颈动脉IMT增厚与补体调节蛋白CD55表达降低相关，而与补体C3、C4、备解素、补体调节蛋白CD59无直接关系。

Conclusion : The increased IMT might be related with down-regulation of complement regulatory protein CD55 expression , but has no direct association with complement C3 , C4 , properdin and CD59 .

促衰变因子（DAF）属膜补体调节蛋白，是一种锚定于细胞膜表面的蛋白质。

Decay accelerating factor ( DAF ) is a membrane bond complement regulatory protein which could dissociate the C3 , C5 convertase and prevent their formation in vivo in both classical pathway and alternative pathway .

另一方面，众多关于红细胞老化吞噬的研究中，多数针对自身抗体和关于非调理性吞噬的CD47，鲜见系统针对补体调节蛋白的研究。

For the other aspect , most researches referring to senescence RBC phagocytosis focus on auto-antibody and CD47 which regulates the non-opsonization phagocytosis , while little studies are about complement regulatory proteins .

异种移植用人补体调节蛋白在猪血管内皮细胞特异表达的研究

The Studies of Specific Expression of Human CRPs on Endothelium of Pig Transfected with These Genes for Xenotransplantation

补体调节蛋白的种属差异是导致异种移植超急性排斥反应的主要原因。

As we know that the difference of complement regulating proteins in different species was the main cause of acute rejection after xenotransplantation .

人补体膜辅助调节蛋白MCP的基因克隆及其真核表达的研究

Molecular cloning and expression of human complement membrane cofactor protein

构建人补体膜辅助调节蛋白真核表达载体并通过壳聚糖介导转染NIH3T3细胞

Construction of the eukaryotic expression vector of human membrane cofactor protein and transfection NIH 3T_3 cells with chitosan nanoparticles

目的：探讨瑞舒伐他汀对高脂血症患者补体、补体调节蛋白及主动脉脉搏波速度的影响。

Objective To investigate the effect of rosuvastatin on complement , complement regulatory proteins and aortic pulse wave velocity in patients with hyperlipidemia .

目的探讨高脂血症患者补体C3、C4、白细胞补体调节蛋白CD55、CD59和颈动脉内膜中层厚度（IMT）、踝肱指数（ABI）的关系。

Objective To investigate the association between complement C3 , C4 , complement regulatory proteins CD55 , CD59 and carotid artery intima-media thickness ( IMT ), ankle / brachial index in hyperlipidemia .

目的：观察2型糖尿病患者血清补体和外周血白细胞补体调节蛋白表达的变化及其意义，探讨补体调节异常在2型糖尿病血管并发症中的作用。

Objective To investigate the expression changes of complement and complement regulatory proteins , and the relationship between them and vascular diseases in type 2 diabetes .

高脂血症患者血清补体C3、C4、备解素和白细胞补体调节蛋白CD35、CD55、CD59的表达

Expression of Complement C3 , C4 , Properdin and Complement Regulatory Proteins CD35 , CD55 , CD59 in Dyslipidemic Patients

CR1是唯一既对经典、替代及植物凝集素（MBL）3个补体激活途径的，对C3/C5转化酶拥有衰变加速活性，又有辅助1因子裂解C3b和C4b作用的补体调节蛋白。

CR1 has activation to the three pathways of complement activation to enhance decay of the C3 / C5 convertase and helps factor 1 to split C3b and C4b .

补体系统由约30种可溶性及膜结合型蛋白组成，其中近90%的胞浆补体成分及可溶性的补体调节蛋白都是在肝脏（主要是肝细胞）中合成的。

The complement system consists of about 30 soluble and membrane bound proteins , 90 % of plasma complement components and their soluble regulators is synthesized in the liver ( mainly hepatocytes ) .