肝实质细胞

高效液相色谱法测定清肺口服液含药血清中白藜芦醇和大黄素浓度的实验研究肝脏普鲁士蓝染色呈蓝色的含铁血黄素颗粒大量沉着在肝实质细胞和库普弗细胞内。

The Experimental Studies on Determination of the Plasma Concentration of Resveratrol and Emodin in Qingfei Oral Liquid Contained Serum by HPLC A Prussian blue reaction is seen in this iron stain of the liver to demonstrate large amounts of hemosiderin that are present in hepatocytes and Kupffer cells .

为研究胡黄连提取物对四氯化碳（CCl4）或半乳糖胺（DGaIN）损伤原代培养大鼠肝实质细胞的保护作用。

The protective effect of the extracts of Rhizoma Picrorhizae on primary cultured hepatocytes injured by CCl 4 and D-GaIN was studied .

结论在肝脏缺血再灌注时，Bcl2蛋白表达水平异常下调，其抑制细胞凋亡的效能减弱，促使肝实质细胞凋亡增加，加重肝脏缺血再灌注损伤。

Conclusion The down-regulation of the expression of Bcl-2 protein induces hepatocellular apoptosis during hepatic ischemia-reperfusion injury .

目的：研究经无唾液酸胎球蛋白（asialofetuin，AF）修饰后，脂质体达到小鼠肝实质细胞靶向的可能性。

To study the possibility of liposomes to target hepatocytes after being linked with asialofetuin ( AF ) .

前期实验表明HPS在体外特异促进肝实质细胞增殖，对非肝来源的细胞和肝癌细胞没有相应的活性。

Early experiment suggested that HPS stimulated only hepatic parenchymal cell proliferation in vitro , no corresponding activity on non-liver cells or liver cancer cells .

结论ICDH和CHE是反映肝实质细胞受损害及其合成代谢能力下降的敏感指标。

Conclusions ICDH and CHE were sensitive markers of reflecting the damage and liver synthetic metabolism of liver cell .

改进的大鼠肝实质细胞的快速分离及鉴定方法

The Improved Methods of Isolating and Identifying Rat Hepatocytes

而低温保存后的再灌注期间，组织内可见明显的肝实质细胞凋亡现象，且低温保存时间越长的肝脏，再灌注后凋亡细胞数量越多。

The longer the liver cryopreserved , the greater the number of apoptotic cells .

用胶原酶溶液灌注活体大白鼠肝脏得到游离肝实质细胞。

Percoll was used to separate differently aged parenchymal cells of the same rat .

胚胎干细胞向肝实质细胞体外定向诱导分化过程中的肝卵圆细胞

Hepatic Oval Cells Obtained In The Course of Directional Induction and Differentiation of Mouse Embryonic Stem Cells Into Hepatocytes in Vitro

在条纹斑竹鲨肝实质细胞的分离的实验中，我们比较了三种肝实质细胞的分离方法，包括组织块培养法，胰蛋白酶消化法，胶原酶离体灌流法。

Three isolation methods of Lip Shark hepatocytes were compared , including mechanical disruption , enzymatic digestion , and organ perfusion .

谷甾醇葡萄糖苷和卞泽双重修饰肝实质细胞靶向阳性脂质体介导的基因转染和抗乙肝病毒作用

Transfection and anti-HBV effect mediated by the hepatocytes-targeting cationic liposomes co-modified with β - sitosterol - β - D-glucoside and Brij 35

分离培养肝实质细胞，研究孵化温度、给药剂量等对肝实质细胞体外摄取上述两种脂质体的影响。

Hepatic cellular uptake of LP-DDB and BP2B-LP-DDB was evaluated in vitro , including incubation temperature , the dose and the addition of bile .

对肝实质细胞在生理状态下促进其增殖与生物合成，但在肝硬化形成过程脾脏对实质细胞本身未见明显影响。

For the parenchymal cells , the spleen normally promoted their proliferation and protein synthesis ; but during the fibrosis process , spleen had no effects on them .

胆酸修饰的脂质体可作为肝实质细胞靶向的载体，可以通过受体介导的方式促进药物向肝实质细胞内的传递。

Hence , BP2B-LP could be a targeting carrier to facilitate the delivery of the encapsulated DDB into the hepatocytes , possibly via the mechanism of receptor mediation .

苏木精伊红染色发现二氧化硫染毒可引起肝实质细胞坏死，汇管区血管壁增厚并伴有淋巴细胞和单核细胞浸润，中央静脉以及肝窦充血，库普弗细胞增生；

HE staining showed necrosis of hepatocytes , thickened blood vessel wall of portal area with infiltration of lymphocytes and monocytes , hyperaemia in central vein and hepatic sinusoid , hyperplasia of Kupffer 's cell ;

结果采用本方法每头乳猪可分离得到单个肝实质细胞数为（3.5±1.1）×10~9，活性大于90%±2%。

Results We obtained ( 3 . 5 ± 1 . 1 ) × 10 ~ 9 liver cells from each suckling pig , and the cell vitality was more than 90 % ± 2 % .

以上结果表明，五味子乙素对药酶有诱导作用，其引起的肝脏增大主要系肝实质细胞体积增大，同时伴有肝细胞增生。

From these results , it may be concluded that Schizandrin B is'an inducing agent of drug metabolizing enzyme , and the enlargement of the liver caused by Schizandrin B is mainly , due to hypertrophy and to a lesser degree , hyperplasia .

激活素A是一种多功能的细胞因子，参与调节胚胎发育、红细胞分化、肝实质细胞分化、神经细胞存活等生理过程，其作为一种新型炎症介质，对胎儿缺氧有潜在的调节作用。

Activin-A is a kind of multifunctional cytokine involving in many physiological courses such as cell growth and differentiation , early embryonic development , erythropoiesis , liver parenchymal differentiation and neural survival , and exerts potential regulatory function for fetal hypoxia as a new kind of inflammatory medium .

大鼠肝非实质细胞载脂蛋白CⅢ结合位点（受体）的研究

Apolipoprotein C ⅲ Binding Sites ( Receptor ) on Non-Parenchymal Cells from Rat Liver

离心淘洗技术在分离大鼠肝非实质细胞亚群中的应用

Application of centrifugal elutriation technique for isolation of rat liver nonparenchymal cells subgroups

肝非实质细胞在内毒素所致肝细胞损害中的作用

The role of nonparenchymal hepatocytes in lipopolysaccharide-induced

目的通过制备肝非实质细胞悬液并离心淘洗的方法，分离纯化大鼠肝库普弗细胞。

Objective To isolate and purify rat liver Kupffer cell enriched fractions from nonparenchymal cells suspension by centrifugal elutriation technique .

方法采用原位肝脏酶灌注、肝非实质细胞悬液的准备、离心淘洗和原代培养等方法进行分离。

Methods The techniques included : ① liver perfusion in situ , ② preparation of nonparenchymal cells suspension , ③ centrifugal elutriation , ④ primary culture .

移植物抗宿主疾病反映的是胆小管内黄棕色的胆汁淤积，同时肝实质慢性炎细胞浸润。

The graft versus host disease here is marked by yellow-brown collections of bile in the canaliculi , as well as chronic inflammatory cells within the liver parenchyma .

高糖膳食对大鼠肝实质及非实质细胞VLDLHDL及载脂蛋白CⅢ受体的影响

Effects of High-Carbohydrate Diet on VLDL - , HDL - , and Apolipoprotein C ⅱ - Receptor Activities on Liver Parenchymal and Non-Parenchymal Cells in Rats

结论CHAIDANWU阻滞CCl4诱导大鼠肝硬化的作用，这种作用可能与抑制肝非实质激活，细胞因子释放减少，贮脂细胞释放TIMP-1壁降低，胶原纤维分解加速，肝细胞凋亡数减少有关。

Conclussion : CHAIDANWU inhibits of rat cirrhosis induced by CCl-4 , which Correlates with depressing the activity of kupffer cell , reducing the cytokine release and TIMP-1 release by HSC , and lowering hepatic cell apoptosis .

大鼠肝实质及非实质细胞分离和质量检测

Isolation and characterization of hepatic parenchymal and nonparenchymal cells from rats

刺激单核巨噬细胞对肝实质及非实质细胞脂蛋白代谢的影响

Effects of monocytic macrophage stimulation on lipoprotein metabolism of rat parenchymal and nonparenchymal cells

网状纤维主要分布在汇管区、纤维隔、炎症区、肝窦旁、实质细胞周围；

Distribution of reticular fiber was similar to collagen fiber , besides around hepatocyte circumference .