组蛋白变体
- 网络histone variant
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更加专门化的组蛋白变体在一些谱系中进化到执行额外的功能。
Further specializations of histone variants have evolved in some lineages to perform additional tasks .
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组蛋白变体及组蛋白替换
Histone Variants and Histone Exchange
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对组蛋白变体的研究是近年来表观遗传学新的研究热点,也是对组蛋白密码的新的诠释。
Recently , research on histone variants is not only a new hotspot in epigenetics , but also a new annotation of " histone code " .
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组蛋白变体是特殊状态下染色体组装所需的组蛋白类型,一般通过替换常规组蛋白导致染色体重塑进入核小体,能在表观遗传学水平调控基因的转录。
Histone variants are the special chromosome histone types required for chromatin assembly at specific chromosome region , and it can replace the conventional histone via chromatin remodeling to exercise its function to regulate gene transcription under epigenetic level .
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组蛋白的变体和翻译后修饰共同参与染色质修饰和基因的表观遗传调控。
Histone posttranslational modifications and sequence variants jointly participate in modification of chromatin and regulation of gene expression .