类固醇受体
- 名steroid receptor
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卵巢癌类固醇受体表达与DNA水平及S期比例之间的关系
The Relationship of Steroid Receptor Expression with DNA Ploidy Level and S-phase Fraction in Ovarian Carcinoma
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目的观察小鼠烧伤后早期类固醇受体辅活化子(SRC)蛋白表达的时相变化,初步探讨烧伤早期糖皮质激素抵抗的分子机制。
Objective To observe the changes of expression of steroid receptor coactivators ( SRC ) during the early stage in the burned mice , and the mechanism of glucocorticoid resistance ( GCR ) .
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类固醇受体辅助活化因子-1(steroidreceptorcoactivator-1,SRC-1)是脑内分布最广泛的类固醇受体辅助活化因子,参与了雌激素受体、雄激素受体等多种类固醇受体对把基因转录的调节。
Steroid receptor coactivator-1 ( SRC-1 ) is the most widely distributed steroid receptor coactivator in the brain . It participate the regulation of several kinds of steroid receptors for gene transcription .
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类固醇受体辅活化子SRC-1和SRC-3在烧伤小鼠应激调控中的作用与机制研究
The Study of the Role and Mechanism of Steroid Receptor Coactivator-1 and - 3 in Modulation of Stress after Burn Injury
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目的探讨类固醇受体辅活化子-1(SRC-1)、核受体辅阻遏子(NCoR)在雄激素非依赖性前列腺癌(AIPC)的表达及临床意义。
Objective To explore the expression of steroid receptor coactivator-1 ( SRC-1 ) and nuclear receptor corepressor ( NCoR ) in androgen independent prostate cancer ( AIPC ) and its clinical significance .
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卵巢上皮性癌类固醇受体临床意义探讨
Clinical significance of steroid receptors in ovarian epithelial cancer
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类固醇受体辅活化因子家族与乳腺癌
Steroid Receptor Coactivator Family and Breast Cancer
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类固醇受体辅活化子-3基因敲除小鼠的繁殖与鉴定两种离子源技术GC/MS法检测蔬菜中多类除草剂的残留量
Breeding and identification of SRC-3 knock-out mice Determination of herbicide residues in vegetables by GC-MS with two different ionization techniques
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结论抑制类固醇受体辅活化因子的表达及其相关信号通路可能是今后预防和治疗乳腺癌的一种有效途径。
Conclusion Inhibition of the expression and signaling pathway of steroid receptor coactivators may be effective for breast cancer prevention and treatment .
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摘要目的探讨类固醇受体辅活化因子家族在乳腺癌发生、发展、治疗、预后等方面的作用。
Objective to investigate the effect of steroid receptor coactivator family in initiation , development , treatment and prognosis of breast cancer .
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类固醇受体辅活化子-1和核受体辅阻遏子在雄激素非依赖性前列腺癌的表达及临床意义
Expression and clinical significance of steroid receptor coactivator-1 ( SRC-1 ) and nuclear receptor corepressor ( NCoR ) in androgen independent prostate cancer
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不同剂量及不同作用时间的米非司酮对早期妊娠药物流产及人子宫蜕膜类固醇受体表达的影响
The Effects of Different Dose and Time of Mifepristone on the Effectiveness of Medical Abortion and the Expression of Steroid Hormone Receptor in Human Decidua in Early Pregnancy
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作为核受体和其它转录因子的转录辅激活因子,类固醇受体辅激活因子-3(SRC-3/AIB1)对于动物的生长和发育是不可或缺的,并且参与了乳腺癌的发生。
As a transcriptional coactivator for nuclear receptors and other transcription factors , steroid receptor coactivator-3 ( SRC-3 / AIB1 ) is required for animal growth and reproductive development and implicated in breast carcinogenesis .
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结果类固醇受体辅活化因子是多种类固醇激素与类固醇受体结合并发挥生物学活性的必需因子,是诱导乳腺癌发生、发展和复发的重要辅助因子,同时也是判断乳腺癌预后的重要预示因子。
Results Steroid receptor coactivators are essential for several kinds of steroid hormones binding to steroid receptors , so they are important accessory factors that induce the initiation , development and recurrence of breast cancer , and predictive factors that estimate the prognosis of breast cancer .
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类固醇激素受体辅激活子3(SRC-3)在小鼠腹膜炎中的作用及抗炎药物的筛选
Role of Steroid Receptor Coactivator 3 in Escherichia Coli Peritonitis of Mice and Anti-inflammatory Drug Screening
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类固醇激素受体共活化因子3(SRC-3)在天然药物治疗恶性血液病中的意义
The Importance of Steroid Receptor Coactivator-3 ( SRC-3 ) on the Treatment of Malignant Hematological Diseases by Natural Drugs
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结论RU486具有抗肿瘤作用,对不同类固醇激素受体状态的乳腺癌细胞其抗肿瘤作用的机制不同。
Conclusion RU486 has antitumor effect , but has different antitumor mechanism between steroid hormone receptor positive and negative breast cancer cell lines .
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滤泡上皮源性甲状腺癌的性类固醇激素受体的临床病理研究
Expression of sex steroid hormone receptors ( SSHR ) in thyroid carcinoma
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海马类固醇激素受体系统对天敌应激所致的内分泌变化的调节效应
Regulatory role of steroid receptor system in hippocampus on the endocrinal responses of rats following predatory stress
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大肠癌组织中类固醇激素受体与淋巴结转移及预后的相关性
The relativity of steroid hormone receptor in tissue of large intestine carcinoma with lymphatic metastasis and prognosis
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乳腺癌核仁组成区和类固醇激素受体与临床病理关系的研究
Correlation of NOR and Steroid Hormone Receptors ( SR ) With Clinical and Pathological Teatures of Human Breast Cancer
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开发选择性类固醇激素受体调节剂有望成为未来防治骨质疏松药物的研究方向。
To develop a new selective steroid receptor modulator is one of the targets in future study to treat osteoporosis .
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天敌应激对大鼠海马神经元的损害作用及海马类固醇激素受体系统对精神应激反应的调节效应研究
Hippocampal Neuronal Lesion of Rats Following Predator Stress and Regulatory Role of Steroid Receptor System in Hippocampus on the Psychological Stress Responses
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维生素D受体是类固醇激素受体超家族的成员,与骨化三醇结合后能调节血钙和骨矿化。
Vitamin D receptor belongs to steroid-hormone receptor superfamily , and binds with calcitriol to regulate blood calcium and mineralization of bone .
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还运用免疫细胞化学方法,对乌梢蛇卵巢及臭腺内的3种性类固醇激素受体和芳香化酶的表达情况进行了初步研究。
The expression of sex steroids receptors and aromatase in the ovary and the scent gland of the Zaocys dhumnades were studied by immunocytochemical method .
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目的通过不同方式的天敌应激,对大鼠内分泌改变进行观察,阐明海马类固醇激素受体系统对精神应激反应的调节机制。
Objective To investigate the effects of different mode of predatory exposure stress on the endocrine aspect of rats , and explore the regulating mechanism of steriods receptors in hippocampus on psychological stress responses .
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这些结果将有助于深入探讨昆虫中雌激素相关受体的具体功能,对于搞清昆虫中类固醇激素受体在昆虫发育以及其它生理方面的关系奠定理论基础。
These results may be useful in further discussing the important functions of estrogen related receptor of insect , and hlpe to lay the theory foundation to make clear the relationship of insect steroid hormone receptors in the development and others physiological aspects .
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多种类固醇/甲状腺受体家族的成员参与了CRH基因的表达调控,例如糖皮质激素受体,雌激素受体和雄激素受体等。
Several members of steroid / thyroid receptor family have been suggested in the regulation of CRH gene expression .
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在卵泡的生长发育过程中,性类固醇激素及其受体有很重要的调控作用,原癌基因的表达也与卵子发生有着密切的关系。
In the development of oocyte , pro-oncogene , sex steroids and their receptors play important roles .