神经兴奋
- 网络nerve impulses;nervousess
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其中当交感神经兴奋性起主导作用时,最大Lyapunov指数增大,反之减小。
And when sympathetic nerve excitability acts dominantly , the Lyapunov index will eliminate .
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自噬/溶酶体途径在NMDA受体介导的神经兴奋性毒性中的作用
Roles of an Autophagy / lysosomal Pathway in Excitotoxicity Mediated by NMDA Receptor
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结果5s组的平均神经兴奋传导抑制时间为(36.8±10.2)min;
Results The mean neural conduction inhibition time 5 s group in which was ( 36.8 ± 10.2 ) min ;
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SIP是一个复杂的超常行为,它的调控机制涉及到神经兴奋、应激、焦虑和情感动机等多个环节。
The mechanisms of SIP are complicated , which may widely involve neural activity , stress , anxiety , emotion and so on .
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如果能及时、有效地选择性干预局部受累脑区NR过度激活所介导的神经兴奋毒性,将为上述疾患提供有效的防治手段。
Efficient prevention and cure measures should interrupt the neurotoxicities induced by the over-activated NMDA receptor ( NR ) in local brain effectively and timely .
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结论大鼠磨牙移动时对牙齿产生伤害性刺激,引起牙髓末梢神经兴奋大量释放CGRP等神经肽,导致牙髓神经纤维中CGRP含量发生动态变化。
Conclusion The rat tooth movement stimulates the pulp nerves to release CGRP , which cause the variation of CGRP in the rat tooth pulp .
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结果提示,PGE2与BK可能是引起血管周围感觉神经兴奋和CGRP释放的主要炎症介质。
Our data indicate that PGE2 and BK are the major inflammatory mediators in triggering the release of CGRP from the perivascular CGRP-containing nerve .
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嗅神经兴奋性输入在鲫鱼Mauthner细胞上的定位
Localization of Excitatory Inputs from the Olfactory Nerve to the Crucian Carp Mauthner Cell
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目的探讨抑制褪黑素(melatonin,MT)分泌对交感神经兴奋性水平的影响,及MT与中医学阴之间有否类同之处。
Objective To investigate the influence of melatonin ( MT ) ischesis on the level of sympathetic excitability , and the similar points between MT and Chinese medical concept of yin .
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结果:虚热时交感神经兴奋,肾上腺皮质素释放增多,ANAE%,PFC空斑数增多,NK活性降低,血内纤维蛋白原增多。
Results : Deficiency of Hot syndrome group : The sympathetic N. S. excited , adrenal cortex hormone release increased , ANAE % , PFC increased , NK cell activity decreased .
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结果:压榨5s组的平均神经兴奋传导抑制时间为(35.1±16.6)min;肌纤维钙泵活性正常。
RESULTS : In the 5 s squeezed group , the average inhibition time of stimulation conduction was ( 35.1 ± 16.6 ) minutes , and the Ca pump activity of muscle fibers was normal .
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结论在CPT中,交感神经兴奋对颈内动脉内径的影响比对大脑中动脉和椎动脉内径的影响要小,因此,颈内动脉Vm的变化能较准确地反映其实际血流量的变化。
Conclusions During CPT , the diameter of ICA was less affected by sympathetic activation than that of MCA or VA , so the Vm of ICA reflected its actual flow volume more accurately .
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事先静脉注射阿片受体阻断剂纳络酮(naloxone,Nal)均可以阻断这两种效应,但单独使用Nal对脾交感神经兴奋性没有影响。
This effect could be blocked by intravenous injection of opioid receptor antagonist naloxone ( Nal ), while Nal alone injected intravenously had no effect on the splenic nerve activity .
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OSAHS可能经氧化应激,睡眠中断引起炎症反应及交感神经兴奋性改变等多条途径影响并导致冠心病发生率增高。
OSAHS maybe through multi-ways ( oxidative stress , sleep interruption ) cause inflammatory reaction and adrenergic nerve excitability change to impact and induce the incidence rate of CHD increased .
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IBS发病机制的研究在不断进步。肠道感染的先驱病史可能改变肠黏膜免疫系统,使传入神经兴奋性增高,进而导致肠道动力异常。
Recent advances in the research of IBS demonstrated that predisposing factors such as intestinal inflammation may contribute to changes in the intestinal mucosal immune system , resulting in hypersensitivity of afferent nerves and abnormal intestinal motility .
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血管紧张肽II受体1拮抗药通过抑制血管紧张肽II和其受体1的结合,从而发挥扩张血管、排钠利尿、抑制交感神经兴奋等作用,在高血压、心力衰竭等的治疗中发挥重要作用。
Angiotensin II type 1 receptor blockers exert the effect of dilating vessel , natriuresis and inhibiting sympathetic activity through inhibiting the combination of angiotensin II with its type 1 receptor . Angiotensin II type 1 receptor blockers play important role in the treatment of hypertension and heart failure .
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结论MT分泌不足可促使青春期前大鼠交感神经兴奋性水平上升,而滋阴泻火方药可有效逆转这种变化,推测MT与阴有一定关系。
Conclusion MT hyposecretion can improve the sympathetic excitability in prepuberal rats , while the prescriptions with the effects of nourishing yin and purging fire can reverse these changes . There may be a relationship by inference between MT and Chinese medical concept of yin .
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药物配体与GABA受体相应位点结合可以增加GABA对GABA受体的作用,从而在抑制中枢神经兴奋以及治疗精神紊乱等疾病中发挥重要作用。
The effects between GABA and GABA receptors would be strengthened when drug ligands binding with corresponding sites in GABA-A receptor , thus , the effects play an important role in inhibiting the excitation in CNS and dealing with diseases related to mental disorders .
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LBNP作用时尽管有外周血管交感神经兴奋现象,但血压变异性谱参数均未发生显著改变,表明这两者在心肺压力感受器卸荷时的变化趋向存在差异。
Although there was increase in sympathetic nerve outflow to peripheral blood vessels during LBNP , significant change in relevant systolic and diastolic blood pressure variability power spectral components was also not observed .
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因此,冠脉造影可使ADM(13-52)及ET-1均升高,可能与造影剂对血管刺激、导管直接对血管内皮的刺激及交感神经兴奋性增高有关。
Conclusion CA made the concentrations of ADM ( 13 - 52 ) and ET - 1 elevated , it may be related to factors including the vascular stimulation of angiographic contrast agents or of catheters , and the over excitement of sympathetic nerve systems .
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结论:冲击波损伤后实验眼房水神经兴奋性相关氨基酸含量改变明显,以伤后20d更加显著,其改变可能与预后相关。
Conclusion : The value of excitatory-related amino acids in aqueous fluid increased significantly after blast injury . This change was more obvious after 20 days . The change might be related with prognosis .
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对东亚钳蝎抗神经兴奋肽(ANEP)同源性分析表明:ANEP与蝎昆虫抑制性神经毒素高度同源,ANEP应属于这一家庭,它们都作用于钠离子通道,是钠离子通道抑制剂。
Multiple alignments show ANEP is homologic with depressant insect neurotoxin , and it belongs to this family , they all affect Na ~ + channel .
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BK通道(Ca2+激活的电压依赖的K+通道)在很多重要的生理过程中起着非常重要的作用,比如神经兴奋性,耳毛细胞的频率调节和平滑肌细胞的收缩和免疫。
BK channel , Ca2 + - activated voltage-dependent K + channel plays a crucial role in modulating a number of important physiological processes , such as neuronal excitability , frequency tuning of hair cells , smooth muscle contraction , and immunity .
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目的在不同电刺激下观察不同刺激强度的电诱发听性脑干反应(electricalevokedauditorybrainstemresponse,EABR)I波幅值的变化,评估刺激强度对豚鼠听神经兴奋性影响。
Objective To evaluate the effect of electrical stimulus intensity on excitability of the auditory nerve at high-rate stimulation via recording the change of amplitude of the electrically evoked auditory brainstem response ( EABR ) of guinea pig .
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利鲁唑对氯化锰致大鼠神经兴奋毒性的影响
Antagonism of Riluzole to Excitotoxicity Induced by Manganese Chloride in Rats
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喹啉酸的螺旋神经节神经兴奋毒性研究
Studies on neurotoxic effects of quinolinic acid on spiral ganglion
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膜离子通道阻断剂对神经兴奋性及兴奋性指标的影响
Effects of specific ionic channel blockers on nerve excitability and excitability indexes
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刺激电极在鼓阶内位置对听神经兴奋性的影响
Effect of Electrode Position in Scala Tympani on Excitability of Auditory Nerve
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膜离子通道闸门调制剂对神经兴奋性的影响
Effects of gating modifiers of membrane ionic channel on excitability of nerves
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方法:应用神经兴奋性测试仪测试失神经支配程度。
Methods : Denervation degree was measured with nerve excitability measurement apparatus .