纤维蛋白酶

链激酶（Streptokinase，SK）是世界上最早发现的纤维蛋白酶原激活剂，也是最早作为临床药品治疗血栓性疾病的溶栓酶。

Streptokinase ( SK ) was discovered as the first plasminogen activator in the world , and it was the earliest clinical agent to cure thrombus .

目的研究猪胆汁性肝纤维化时尿激酶型纤维蛋白酶原激活物（uPA）和基质金属蛋白酶2（MMP2）的表达，分析其在肝纤维化形成初始阶段的作用。

Objective To observe the expression of the matrix metalloproteinase-2 ( MMP-2 ) and urokinase plasminogen activator ( uPA ) in the early stage of liver fibrosis .

通常情况下，MMPs受多层次的调控并以酶原的形式存在，激活过程受丝氨酸蛋白酶或纤维蛋白酶的介导，也可以自主催化激活，此外还受其特异性组织抑制剂（TIMPs）的调节。

Normally MMPs exist as zymogen in the inactive form and their modulations are controlled at multi-levels . Their activations are mediated by serine protease or fibrinase . In addition , they can also be activated by autocatalysis and modulated by their specific tissue inhibitor of MMPs ( TIMPs ) .

去纤维蛋白酶治疗急性心肌梗塞的临床观察

Clinical Observation of Treatment of Acute Myocardial Infarction by Defibrase

泰国人黄斑下出血玻璃体腔内注射组织纤维蛋白酶原激活剂和气体填充的治疗效果

Results of intravitreal tissue plasminogen activator and expansile gas injection for submacular haemorrhage in Thais

研究者也发现骨桥蛋白基因的表达触发了纤维蛋白酶原基因的表达。

The researchers also found that osteopontin gene expression triggered the expression of profibrogenic genes .

纤维蛋白酶及其对乳制品的影响

Plasmin and its influence on dairy products

纤维粘连蛋白酶切片段的制备及其对大白鼠血浆中冷凝蛋白形成的抑制作用

Preparation of fibronectin fragments and its inhibition to the cold insoluble protein formation in rat plasma

凝血酶激活真皮成纤维细胞蛋白酶激活受体-1释放白细胞介素-8及金属蛋白酶的信号通路研究

Signaling Pathways Involved in Protease-Activated Receptor-1 Mediated Thrombin Induced Interleukin-8 , MMP-2 and MMP-9 Production in Dermal Fibroblasts

根据羊毛纤维、蛋白酶的性质，设计了单种蛋白酶的防毡缩实验、多种蛋白酶的复配正交实验。

According to the nature of wool fiber and protease , we have done the single and complicated species of protease anti-shrinkage experiments .

核转录因子AP-1顺式诱骗元件抑制博莱霉素引起的肺成纤维细胞基质金属蛋白酶-2/金属蛋白酶组织抑制剂-1失衡

AP-1 Decoy modulating MMP-2 / TIMP-1 imbalance induced by bleomycin-A5 in pulmonary fibroblasts

人参皂苷Rb1与芳维甲酸乙酯对光老化皮肤真皮成纤维细胞基质金属蛋白酶影响的比较研究

Comparative Study of the Effect of the Ginsenoside Rb_1 and Arotinoid Ethyl Ester on the Expression of MMPs in Sun-induced Aging Dermis Fibroblasts

TIMP-2基因转染豚鼠巩膜成纤维细胞基质金属蛋白酶2及其抑制剂的表达

The Expression of Matrix Metalloproteinase-2 and Its Tissue Inhibitor in the Sclera Fibroblast Cell of Guinea Pig with the Transfection of TIMP-2 Gene

实验证明拉坦前列素可上调Tenon囊成纤维细胞基质金属蛋白酶的表达，促进胶原和其它细胞外基质的分解过程。

Latanoprost stimulates secretion of matrix metalloproteinases in Tenon fibroblast both in vitro and in vivo , which may degrade collagen and other extracellular matrix .

结论PUVA治疗引起的皮肤光老化皱纹形成可能与真皮成纤维细胞基质金属蛋白酶及其组织抑制剂表达失衡密切相关。

Conclusion Wrinkle formation in photoaging skin after PUVA therapy is correlated with the imbalance of expression of matrix metalloproteinases and their inhibitors of dermal fibroblasts .

TGF-β1对人胚肺成纤维细胞基质金属蛋白酶及其组织抑制因子表达的影响

Effect of TGF - β _1 on the Expression of MMP-1 and TIMP-1 in Human Lung Fibroblasts in vitro

雌激素对人成纤维细胞基质金属蛋白酶-12、赖氨酸氧化酶基因表达的影响

Effects of estrogen on the expression of matrix metalloproteinase-12 、 lysyl oxidase gene in human dermal fibroblasts in vitro

不同浓度雷公藤甲素对光老化皮肤成纤维细胞基质金属蛋白酶的影响：以维甲酸为标准对照

Effect of different concentration triptolide on matrix metalloproteinase in fibroblasts of light-induced aging dermis : arotinoid ethyl ester is considered as standard control