法莫替丁

pH非依赖释放型法莫替丁缓释片的研制

Preparation of famotidine pH-independent sustained release tablets

用HPLC柱切换法血浆直接进样测定法莫替丁

Direct injection of plasma to determine famotidine in plasma using HPLC column switching technique

西奥多H法莫替丁指出两个基本运动仪式。

Theodor H Gaster has pointed out two basic movements in rituals .

流动注射能量转移荧光素罗丹明B化学发光法测定法莫替丁

Determination of famotidine by flow injection chemiluminescence method based on energy transfer to fluorescence substance Rhodamine B

前列腺素E1联合法莫替丁治疗高原地区消化性溃疡的疗效观察

Clinical observation about prostaglandin E_1 combined famotidine treatment of peptic ulcer at high altitude

HPLC法测定复方法莫替丁咀嚼片的含量

Determination of Famotidine in Compound Famotidine Chewable Tablets by HPLC

HPLC法测定人血浆中法莫替丁浓度

Studies on HPLC Analysis of Famotidine in Plasma

柱切换HPLC法测定法莫替丁血药浓度及其在药动学研究中的应用

Column switching HPLC method for determination of famotidine in human plasma and its application in pharmacokinetics study

结果：在48小时内，法莫替丁能明显提高胃内pH值，并能维持这个高的pH值（P<0.01）。

Result : Famotidine can obviously lift the value of gastric acid pH and can keep this high pH within 48 hours .

方法：将93例患者随机分为A、B、C三组，A组给予瑞巴派特+法莫替丁+阿莫西林+甲硝唑；

Method : 93 examples were divided into A 、 B 、 C three groups at random , A : rebamipide + famotidine + amoxicillin + metronidazole ;

RP-HPLC测定复方法莫替丁咀嚼片中法莫替丁的含量及有关物质

Determination of famotidine and related substances in its chewable tablets by RP-HPLC

法莫替丁联合阿莫西林、甲硝唑治疗DU合并Hp感染的临床研究

Clinical Research on the Famotidine plus the Amoxicillin and Metronidazole Treating the DU Complicating Hp Infection

UV法及Weibull模型评价复方法莫替丁分散片的溶出特性

Evaluation on Dissolution Properties of Compound Famotidine Dispersible Tablets by UV Method and Weibull 's Distribution

法莫替丁联合无环鸟苷治疗HSV感染性上皮性角膜炎124例

Clinical observation of 124 cases of HSV corneal ulcer treated by famotidine and acyclovir

应用法莫替丁，替硝唑，枸橼酸铋胺，三联2周疗法对HP阳性者行根除治疗，同法检测根除疗效。

People with HP positive infection were treated with famotidine , tinidazole , bismuth , and ammonium citrate for 2 weeks .

法莫替丁及西咪替丁对Oddi括约肌压力变化的影响

Effects of famotidine and cimetidine on human sphincter of Oddi pressure

目的：法莫替丁（famotidine）是第3代H2受体拮抗剂，其作用为西咪替丁的20倍，雷尼替丁的7.5倍，是治疗消化性溃疡及十二指肠溃疡的强效药物。

Obejective : Famotidine is a new H2-receptor antagonist and very effective in the treatment peptic ulcer and duodenum ulcer .

背景：法莫替丁作为组胺H2受体拮抗剂，其口服吸收不完全，生物利用度约为37%-50%。

Background : As one of the histamine H_2 receptor antagonist , the oral absorption of famotidine is not complete , its bioavailability is about 37 % - 50 % .

法莫替丁是组胺H2受体拮抗剂，临床上主要用于消化性溃疡和Zollinger-Ellison综合征的治疗。

Famotidine is a histamine HZ receptor antagonist advocated for use in gastrointestinal ulcer and Zollinger-Ellison syndrome .

结论：三种H2受体拮抗剂对壁细胞H2受体脱敏的诱导能力存在一定的差别，其中法莫替丁最强，西咪替丁最弱。

CONCLUSION : Three H2 receptor antagonists can induce different desensitization of the H2 receptor , among which famotidine induces the strongest and cimetidine does the weakest .

结果：法莫替丁组总有效率（100%），高于甲硝唑组（82%）（P＜0.01）；复发率低于对照组（P＜0.05或0.01）。

RESULTS : The marked and total effective rates of the experimental group were higher than those of the control group and the relapse rate of the experimental group were lower than that of the control group ( P < 0.01 or 0.05 ) .

法莫替丁组和兰索拉唑组Hp根除率分别为88.1%和90.0%；十二指肠溃疡和／或胃溃疡的愈合率分别为90.5%和92.5%。

The rate of Hp eradication for Famotidine and Lansoprazole group were 88.1 and 90.0 percent respectively , and the healing rate of peptic ulcer for them were 90.5 and 92.5 percent respectively .

结果：采用转篮法及桨法测定本复方法莫替丁分散片的溶出度，其td值分别为13063及07931min；

Results : The t d value of compound famotidine dispersible tablets determined by the rotating basket and the paddle were 1 3063 and 0 7931 minutes respectively .

应用大鼠实验性胃溃疡模型观察了法莫替丁的一种新结晶型（FA）的抗溃疡作用，并比较了它和目前广泛应用的晶型（FB）抗溃疡作用的强度。

We investigated the effect of a new crystal form of famotidine ( F_A ) on experimental gastric ulcers of rats and compared its antiulcer effect with that of the form B of Famotidine ( F_B ) which has been used widely .

目的：观察35%尿素交连明胶（UG）输入人体后血浆组织胺浓度的变化及H1和H2受体拮抗药（异丙嗪与法莫替丁）的预防效应。

Objective : To observe the change of plasma histamine concentration caused by infusion of 3 5 % gelatine polypetides cross linked via urea bridges ( UG ) and prevention of H 1 and H 2 receptor antagonists ( promethazin and famotidine ) were studied .

方法：106例胃溃疡病人随机分成两组，治疗组口服西沙比利（10mg，4次/日）和法莫替丁（20mg，2次/日）；

Methods ; 106 patients were randomly allocated to treatment with the combination of 10 mg cisapride 4 times daily and 20 mg famotidine twice daily ( the treatment group ) or 20 mg famotidine twice daily ( the control group ) .

法莫替丁治疗反流性食管炎多中心临床观察

Famotidine in the treatment of reflux esophagitis : a multicenter study

硫糖铝联合法莫替丁治疗急性胃炎疗效观察

Effective observation on sucralfate combined with famotidine for treating acute gastritis

法莫替丁、雷尼替丁、西米替丁的药理作用比较

Comparative studies of pharmacologic effects between Famotidine , Ranitidine and Cimetidine

法莫替丁预防脑出血并发上消化道出血疗效观察

Observing the function of famotidine preventing upper gastrointestinal hemorrhage in cerebral hemorrhage