构型翻转

（1R，3S）-樟脑酸制备（1S，3R）-樟脑酸酐过程中构型翻转的研究

Study on configuration reversions for ( 1S , 3R ) - camphoric anhydride prepared from ( 1R , 3S ) - camphoric acid

由于在侧链的合成中，有手性碳原子发生了构型翻转，因此我们合成了一个相应的多利培南光学异构体，以利于质量控制。

Due to the configuration inversions of chiral carbon in the synthesis of side chain , we synthesized the corresponding optical isomer of doripenem for quality control .

以基团次序地位变化为线索，揭示双分子亲核取代反应中，构型翻转与构型标记变化的关系。

The paper shows the relationship between the change of configuration turning and configuration marking , in bimolecular nucleophilic substitution reaction , according to the change order of group .

通过晶体结构和量子化学计算的结果对该化合物中两个手性碳原子同时发生构型翻转进行了讨论。

The reversions in configuration of two chiral carbon atoms at the same time are discussed by means of the results of the quantum chemical calculations as well as its crystal structure .