吡哆醇

大剂量吡哆醇对大鼠睾丸细胞DNA和RNA影响的研究

Effect of high-dose pyridoxine on DNA RNA content in testicular cells of rats

吡哆醇对小鼠肝癌细胞H（22）体外抑制作用的研究

Study of the inhibitory effect of pyridoxine on liver cancer cell line H_ ( 22 ) in vitro

吡哆醇为维生素B族化合物，是机体内一种重要辅酶，它以5′-磷酸吡哆醛的形式参与了氨基酸、脂类等代谢和免疫反应等过程。

Pyridoxol is chemical compound of B vitamins , and important coenzyme in vivo . It participates in metabolism of amino acid and lipids and immune response .

目的探讨吡哆醇（PN）对大鼠睾丸的体外毒性。

Objective To understand the toxic effects of pyridoxine ( PN ) on rat testis cells in vitro .

GB14753-1993食品添加剂维生素B6（盐酸吡哆醇）

Food additive & Vitamin B6 ( Pyridoxine hydrochloride )

结论：吡哆醇可能主要通过损伤Sertoli细胞，引起睾丸结构和功能改变。

Conclusion : The toxic effects of PN on Sertoli cells may contribute to the constitutional and functional change of the rat testes .

大豆吡哆醇生物合成蛋白基因（PDX）的电子克隆和进化分析

In Silico Cloning of Pyridoxine Biosynthesis Protein Gene from Soybean and Evolution Analysis

随饲料中盐酸吡哆醇（PNHCl）添加量的增加，幼虫体内吡哆醇（PN）含量相应变化，其次是吡哆醛（PL）；

With the increase in the pyridoxine hydrochloride ( PN-HCl ) content of the diet , pyridoxine ( PN ) accumulated , and the content of pyridoxal ( PL ) increased in the larval body .

与非超声辐射条件下相比，二氧化锰氧化吡哆醇的氧化速率大大提高，反应时间由5h减至30min。

Compared with that under the common condition , the reaction time for oxidation of pyridoxol to pyridoxal under ultrasonic radiation decreases from 5 h to 30 min.

为探讨大剂量吡哆醇（PN）对睾丸结构和功能损害的分子机制，研究其对睾丸一氧化氮合酶（NOS）和细胞凋亡的影响。

To study the changes of testis NOS and apoptosis in high dose pyridoxine ( PN ) will promote the understanding of the molecular mechanism of high dose PN injurious action on the development and function of testis .

过去的记载提出吡哆醇的水平可以提高。

Evidence from case histories suggests that pyridoxine levels could be increased .

用睾丸细胞共培养探讨吡哆醇对大鼠睾丸细胞的毒性

Effects of pyridoxine on rat testis cells in Sertoli germ cell co culture system

4-脱氧吡哆醇的新合成法

A new synthesis of 4-deoxypyridoxine

吡哆醇的催化极谱波研究

Polarographic Catalytic Wave of Pyridoxine

研究了在超声波辐射条件下，市售二氧化锰在5%HCl溶液中氧化吡哆醇为吡哆醛的反应。

The oxidation of pyridoxol to pyridoxal by the commercial MnO_2 under ultrasonic radiation is investigated in diluted HCl .

另外，建立了伏安电生荧光法用于测定药剂中盐酸吡哆醇含量，结果满意。

In addition , the voltammetrically electrogenerated fluorescence is proposed as a new and sensitive method for assay of pyridoxol with satisfactory results .

临床上对淋巴滞留性脑病患者采用大剂量吡哆醇或泛酸治疗能明显减轻患者症状，说明吡哆醇能够改善大分子物质引流，但其机理不清。

In clinic , the symptoms of the lymphostatic encephalopathy ( LE ) patients obviously relieved by using of high-dose Pyridoxol or bepanthen , which explain that pyridoxol can improve drainage of macromolecular substance . But the mechanism is unclear .