免疫监视

结论：CA患者皮损CD1a和E-cadherin分子表达降低可能导致人乳头瘤病毒（HPV）抗原递呈障碍，在HPV逃逸机体免疫监视的过程中可能发挥重要作用。

Conclusion The decreasing expression of CD1a and E-cadherin may cause the deficiency of human papillomavirus ( HPV ) antigen presentation , and it may play an important role in the process of HPV escaping from immunosurveillance .

结论：LMP蛳1可上调Fas系统，Fas系统在感染EBV淋巴细胞的恶性转化可能起重要作用，通过FasL低表达，影响CTL的功能，抵抗肿瘤的免疫监视所致。

LMP - 1 may up - regulate Fas and FasL . Fas and FasL play an important role in malignant transformation in lymphocyte EBV infected . Lower expression of FasL may influence the function of CTL , which depress immunosurveillance .

TRAIL对HBV感染的免疫监视效应研究

Immune surveillance effect of TRAIL on the HBV infection

结论星形细胞瘤患者存在TAP蛋白分子低表达，推测其促使星形细胞瘤患者肿瘤细胞逃避免疫监视；

Conclusion The low expression of TAP in astrocytoma patients may be an important cause for immunological surveillance not to find the tumor cells .

肿瘤细胞可能通过FasL的过度表达，逃避免疫监视，诱导Fas敏感的TIL凋亡，发生浸润和转移。

Tumor cells may escape from immune surveillance by highly expressing FasL and induce TIL apoptosis and perform infiltration and metastasis .

结论：5-Fu可上调肿瘤细胞Fas表达水平，由此可能增加其对Fas介导的机体免疫监视作用的敏感性。

Conclusion : These data suggest that 5-Fu may enhance Fas expression in tumor cells and may increase the sensibility of them to Fas-mediated immune surveillance of the host .

结论：内异症患者腹腔液Th细胞培养上清液中IFN-γ/IL-4比值的变化揭示Th1/Th2的失衡状态，可导致异位内膜逃避免疫监视，造成异位内膜种植。

Conclusion : The change of IFN-r / IL-4 ratio in endometriosis approves the imbalance state of Th 1 / Th 2 , which leads to endometriosis escaping from immune surveillance , and results in ectopic membrane implantation .

近来研究发现白血病细胞表达多种NKG2D配体，参与白血病的免疫监视。

Currently intensive researches have shown that NKG2D ligands expressed on leukemia cells are involved in leukemia immune surveillance .

目前人类NKT细胞在肿瘤的免疫监视中，发挥保护和抑制作用的潜在基本机制还没有完全阐明。

Human NKT cells in tumor immune surveillance , protection and inhibition of its potential to play a basic mechanism has not yet fully understood .

结论HSPGs可能参与影响HLA-I在HCMV感染的HELF细胞表面上的表达，对HCMV逃避宿主的免疫监视起间接调节作用。

Conclusion HSPGs probably influence the expression of HLA - I on the surface of HCMV infected HELF . HSPGs indirectly regulate the HCMV immune surveillance evasion .

结论胃癌时ICAM-1和VCAM-1表达增高，但可能不足以产生针对肿瘤细胞的宿主免疫监视，反而有利于提高这些细胞的运动能力。

CONCLUSION The expression of ICAM-1 and VCAM-1 in gastric adenocarcinoma was increased , but might not be sufficient for host immune surveillance of the tumor cells , on the contrary it might increase their mobility .

结果肿瘤治疗后体内出现Th1向Th2漂移，使肿瘤细胞逃避机体的免疫监视，导致肿瘤的复发。

Results Th1 / Th2 shift can be detected in the host after therapy of the tumor . Tumor cells escape from host immune surveillance by altering Th1 / Th2 , which could lead to tumor recurrence .

由于诱导中和抗体的抗原表位恰好位于其包膜抗原E2蛋白的高变区1（HVR1），因而容易逃避机体的免疫监视，形成慢性感染，同时造成发展广谱预防性疫苗的困难。

The epitope inducing neutralizing antibody in high variable region 1 ( HVR1 ) is the reason for escape of host immune surveillance , evolution of chronic infection , and also difficulty of producing wide spectrum vaccine .

1971年Burnet首先提出免疫监视学说，认为免疫系统起了监视机体识别和破坏免疫性肿瘤细胞的作用。

Burnet developed the immunosurveillance concept in 1971 . Malignant cells obviously escape immune surveillance , which suggests that they possess the ability of evading any potentially lethal effector mechanisms operated by the immune system .

结论缺乏共刺激分子（如B71）是血液肿瘤细胞逃避宿主免疫监视的重要原因，可能是人类血液肿瘤的发病机理之一；

Conclusion The deficiency of costimulatory molecules ( such as B7-1 ) is an important cause for leukemic tumor cells evading host immunosurveillance and may be one of the mechanisms of human hematologic malignant tumors .

免疫监视下描述肿瘤细胞数量的动力学模型分析

Analysis on a Kinetic Model of Tumors Attacked by Immune System

利用所建立的抗体记忆矩阵实现对类似入侵抗原的快速应答，行使免疫监视识别功能。

The function of antibody memory cells is immune surveillance . quick ;

同时，巨噬细胞在免疫监视中也发挥重要作用。

Macrophage also plays an important role in immune monitoring .

氯丁二烯对小鼠机体免疫监视功能的影响

Effect of chlorobutadiene on the immunosurveillance function of mice

一般认为这是肿瘤细胞逃避了机体免疫监视。

The reason is the tumor cells escape the immunosurveillance whose mechanism is very complex .

肿瘤可以通过多条途径或机制逃逸宿主免疫监视。

Tumor can escape from immune surveillance mechanisms of host self through a number of pathways or mechanisms .

TGF-β1与肿瘤的发生、发展有关，可能使肿瘤细胞逃脱免疫监视。

TGF - β 1 may lower immune function of body and result in cancer cells escaping from immune surveillance .

肿瘤细胞通过逃避机体的免疫监视和攻击，进而在体内不受限制的生长和发生远处转移。

In most cases , escaping from immunologic surveillance and aggression , tumor cells can grow unrestrictedly and metastasize to distant place .

结论：原发肿瘤、放化疗及机体免疫监视系统损害，是导致继发性Ph+/bcr-abl+CML的主要因索。

Conclusion : Primary cancer , radiotherapy , chemotherapy and decreased immunosurveillance were major factors causing second Ph + / bcr-abl + CML .

抗体在免疫监视中的重要作用被逐渐认识，肿瘤免疫预防最终可能成为现实。

As we understand more about the roles of antibody in immune surveillance , it will help to make immunotherapy of tumors a promising strategy .

结论肿瘤细胞可能通过产生某些可溶性蛋白分子抑制淋巴细胞活性，从而逃避宿主免疫监视。

If we use tumour immunotherapy to stimulate organism 's immunologic surveillance system , it is possible to eliminate the remaining tumor cells and cure cancer thoroughly .

异位表达的策略暗示了穿孔素潜在的凋亡诱导活性，而靶细胞的凋亡有助于机体的免疫监视和免疫防御，也提示穿孔素可以作为潜在的药物用于治疗。

The allotropic expression strategy implies the potential apoptosis-inducing ability of perforin which may benefit immune surveillance and defense , and might also be adopted for therapeutic purpose .

虽然机体有着严密的免疫监视系统，但在一定的条件下恶性肿瘤细胞可以逃避机体的免疫攻击，并且对肿瘤抗原产生免疫耐受。

Human has a accurate surveillance system , but tumor cells often escape the immune attack . And the immune system gives rise to immuno-tolerance to the tumor antigen .

还能够迅速刺激机体内巨噬细胞，促使机体对肿瘤的免疫监视作用，促进骨髓增殖，从而增强机体免疫能力。

Meanwhile , SW can activate the macrophages , enhance the action of immunologic surveillance to tumor , and promote bone marrow hyperplasy , and accordingly strengthen the immune competence of body .

肿瘤是严重影响人类健康的一类疾病，肿瘤的形成和发展与宿主免疫监视功能的异常及肿瘤细胞免疫逃避作用密切相关。

Tumor is one of the serious diseases threatening human health . Development of tumors is related to a defect of a host immunosurveillance system and an escape mechanism of tumors from host immune responses .