基因工程抗体

基因工程抗体Anti-HBsAgFab非特异组合层析纯化工艺初步研究

Preliminary Study on Nonspecific Combination Chromatography Purification Technology of Genetically Engineered Antibody Anti-HBsAg Fab

结论用基因工程抗体技术制备抗体是可行的。

CONCLUSION Preparing antibodies by genetic engineered antibody technology is feasible .

高亲和力抗Met人源基因工程抗体scFv的筛选与特性分析

Screening and characterization of high affinity human anti-Met recombinant antibody scFv

人源抗Met基因工程抗体scFv的改造与特性分析

Reconstitution of human anti-Met genetic engineering antibody scFv

人源性抗-D基因工程抗体在真核细胞CHO中的表达

Expression of Human Anti-Rhesus D Antibody in Eukaryotic CHO Cells

目的于真核细胞系CHO细胞中表达人源性抗-D基因工程抗体，为人源性抗-D基因工程抗体在临床上的应用打下坚实的基础。

Objective To express human anti-Rhesus D antibody in eukaryotic CHO cells .

鼠抗人CD2基因工程抗体嵌合Fab的构建和表达

The Construction and Expression of Engineering Antibody Chimeric Fab Rat Against Human CD2

创造性思维的培养&浅谈工笔人物教学改革人源抗Met基因工程抗体scFv的改造与特性分析

The development of creative thought & About the innovation of fine brushwork ; Reconstitution of human anti-Met genetic engineering antibody scFv

目的研究抗人巨细胞病毒（HCMV）人源基因工程抗体。

Objective Cloning recombinant human Fab fragment against HCMV for the purpose of prophylaxis and control of HCMV infection .

vonwillebrand因子功能结构域研究及其A1区基因工程抗体制备

Study on the Domains of von Willebrand Factor and the Generation of Single Chain Fv to Its Domain A1

目的构建人源性抗HFRS病毒基因工程抗体基因的表达载体，为其进一步在真核细胞中表达奠定基础。

Aim To construct anti HFRS virus human engineering antibody expression vectors and then to express it in eukaryotic cells .

基因工程抗体主要包括单链抗体（ScFv）、Fab抗体、F（ab`）2抗体等小分子抗体、嵌合抗体和改形抗体。

Gene engineering antibodies comprise small molecular antibodies of ScFv antibodies , Fab antibodies , F ( ab ′) 2 antibodies and so on .

结论：获得了具有活性的抗角蛋白的Fab抗体，为其应用研究打下了基础，也表明包涵体表达基因工程抗体技术是可行的。

CONCLUSION : The successfully prepared anti-keratin Fab with binding activity to human keratin laid a solid foundation for its further application .

目的表达抗人肺癌单克隆抗体（mAb）LC1的人鼠嵌合基因工程抗体。

Aim To express human mouse chimeric genetic engineering antibody of monoclonal antibody ( mAb ) LC 1 to human pulmonary carcinoma .

结论：原核融合表达的HAb18G胞外区片段可以替代天然的HAb18G蛋白，以用做抗原来筛选新型的基因工程抗体。

CONCLUSION : The extracellular domain of HAb18G expressed in prokaryotic expression system can substitute natural HAb18G protein as antigen to screen new type gene engineering antibody of HAb18G .

随着分子生物学的进一步发展，抗体技术也逐步由细胞工程抗体向基因工程抗体演替，特别是单链抗体（ScFv）在理论和应用方面的研究令人尤为关注。

With the developing of molecular biology , Antibody technology has a succession from cell engineered antibody to genetically engineered antibody , especially the study of single-chain variable fragment ( ScFv ) is concerned in theory and application .

抗血小板膜糖蛋白基因工程抗体的制备和性质研究

Preparation and Characterization study of Gene Engineering Antibody against Platelets GP

抗人血管生长素噬菌体基因工程抗体库的构建

Construction of library of the phage genetic engineering antibody of anti-human angiogenin

基因工程抗体表达系统的研究进展

The advances in study of genetic engineered antibody expression systems

九十年代兴起的噬菌体抗体库技术是组合技术与基因工程抗体技术相结合的产物，是抗体工程领域的重大进展，代表着抗体工程的前沿。

Phage display technique is the combination of combinatorial technology .

流感病毒血凝素基因工程抗体的抗病毒实验效果观察

Antiviral effect of recombinant antibody to influenza virus HA antigen

基于表位预测的抗B型肉毒毒素基因工程抗体的研究

Research of Genetically Engineered Antibody Against BoNT / B Based on Epitope Prediction

基因工程抗体中噬菌体抗体库技术的应用

Applying phage antibody library technique in genetic engineering antibody

单克隆抗体技术的发展&基因工程抗体

Development of monoclonal antibody technology & genetic engineering antibody

增强基因工程抗体表达策略的初步探讨

The Primary Study of Strategy for Enhancing the Expression of Genetic Engineered Antibody

本文就基因工程抗体制备的新技术简要综述。

This article reviewed the new technique of antibody preparation from genetic engineering .

简要论述了基因工程抗体的种类及应用前景。

Categories and prospect for application of genetic engineering antibody were simply discussed .

昆虫表达系统及其在基因工程抗体中的应用

Insect Expression Systems and Their Application in Antibody Engineering

基因工程抗体与制备技术的研究及应用

The Research on and Application of the Genetic Engineering Antibodies and Their Preparation Techniques

抗体技术由细胞工程抗体（杂交瘤-单克隆抗体）发展到基因工程抗体，尤其是抗体库技术的出现，将抗体工程发展到了一个新阶段。

Antibody technology has been developed from cellular engineering antibody to genic engineering antibody .