克罗米酚

克罗米酚对继发性不孕患者子宫内膜组织形态及E2和P的影响

The Effect of Clomiphene Citrate on Endometrial Glandular Epithelium and E 2 , P of Secondary Infertile Patients

雌激素和克罗米酚对致癎大鼠海马γ-氨基丁酸免疫反应细胞和GABAA受体α1亚单位表达的影响

Effects of estrogen , clomiphene on gamma-aminobutyric acid immunoreactive cell and α 1 subunit of GABA_A receptor in hippocampus of epileptic rats

方法：拟行促排卵治疗的多囊卵巢综合症（PCOS）患者（66例），分为来曲唑组（20例）和克罗米酚组（46例）。

Methods : The patients with polycystic ovarian syndrome ( PCOS ) undergoing ovarian stimulation were divided into LE group and CC group .

目的：探讨血清基础卵泡刺激素（FSH）和克罗米酚兴奋实验（CCT）预测不孕症患者卵巢储备功能的价值。

Objective : To study the predictive value of basal serum hormone levels and clomiphene challenge test ( CCT ) were carried out in infertile patients .

目的：探讨二甲双胍（MTF）治疗多囊卵巢综合征（PCOS）不孕患者克罗米酚（CC）抵抗的效果。

AIM : To observe the treatment effect of metformin ( MTF ) on clomiphene ( CC ) - resistant infertile patients with polycystic ovary syndrome ( PCOS ) .

结果用克罗米酚促排卵94个周期中排卵率为552%（52/94），未排卵组的基础血雄激素、LH、AUCI和BMI均较排卵组高。

The basal serum A , LH levels , AUC I and body mass index ( BMI ) in anovulation group were higher than those in ovulation groups .

[方法]不孕妇女42例随机分为克罗米酚（CC）治疗组、绝经期妇女尿促性腺激素（HMG）治疗组和中西医结合（CC+TCM）治疗组。

[ Methods ] Forty - two cases of infertility were treated with clomiphene citrate ( CC ), human menopausal gonadotropins ( HMG ) and CC combined with TCM respectively .

目的：研究超声引导下经阴道卵巢打孔术（TOD）治疗克罗米酚（CC）耐药性多囊卵巢综合征（PCOS）不孕患者的排卵和妊娠情况。

Objective : To study the follicle development and pregnancy in CC-resistance Polycystic Ovarian Syndrome ( PCOS ) patients with anovulatory infertility after the therapy of ultrasound-guided transvaginal ovarian drilling ( TOD ) .

方法符合标准的患者67例服用LE治疗，记录卵泡发育、子宫内膜生长、宫颈黏液性状等指标，并与同期使用克罗米酚（CC）治疗患者进行比较。

Methods : Sixty-seven patients were treated with LE . The indices of their follicle growth , endometrial development and cervix mucus score were observed and compared with those in the women treated with clomiphene citrate ( CC ) .

方法对23例耐克罗米酚PCOS患者的临床资料进行回顾性分析，比较二甲双胍治疗前后各项内分泌代谢指标的变化及其对恢复月经、促排结局及妊娠的影响。

Methods A total of 23 PCOS patients with CC resistant-anovulation were collected and treated by metformin to evaluate its effect on menstruation , ovulation and pregnancy by comparison of sex hormone , fasting glucose , insulin levels in PCOS patients before and after metformin therapy .

治疗观察112例排卵障碍性不孕症，西医组55例采用人工周期及克罗米酚治疗；

Cases of sterility due to anovulation were treated in different therapies .

克罗米酚促排卵周期中卵巢囊肿的基线特征

Characteristics of baseline ovarian cysts in clomiphene citrate ovulation cycles

二甲双呱及联合克罗米酚诱发多囊卵巢综合征排卵

Metformin on Spontaneous Ovulation and Clomiphene on Induced Ovulation in Polycystic Ovary Syndrome

对照组为单纯应用克罗米酚，观察排卵率及妊娠率。

The ovulation rate and pregnant rate were observed .

对照组45例：单纯运用克罗米酚治疗。

The control one 45 cases only Clomiphene .

克罗米酚对子宫内膜发育、血管生成和子宫血流的影响

Effects of clomiphene citrate on the endometrial development , angiogenesis and the uterine blood flow

中药纠正克罗米酚促排卵致低雌激素状态的临床观察

Clinical Observation on Effect of Chinese Herbs in Adjusting Hypoestrogenemia Status by Clomiphene to Promote Ovulation

克罗米酚抵抗性不排卵的针刺治疗&附40个月经周期的临床观察

Acupuncture treatment of clomiphene-resistant anovulation

治疗后克罗米酚促排卵成功率为72%，明显高于治疗前20%（P<0.01）。

The ovulation rate by clomiphene citrate stimulating therapy was 72 % and significantly higher than that before treatment .

结论克罗米酚在诱发排卵过程中可导致内源激素平衡紊乱。

Conclusion Clomiphene therapy can lead to the disorder of estrogen and progesterone level during the course of ovulation induction .

[目的]观察中医周期疗法配合克罗米酚治疗排卵障碍性不孕的临床疗效。

[ Objective ] To observe the clinical effect of dysfunctional ovulatory sterility treated with TCM periodic therapy combined with Clomiphene .

目的研究克罗米酚对子宫血流、子宫内膜发育及血管生成的影响。

Objective To study the effects of clomiphene citrate ( CC ) on the endometrial development , angiogenesis and the uterine blood flow .

[结论]中西医结合治疗排卵障碍性不孕较单纯运用克罗米酚疗效好，能提高妊娠率，减低流产率。

[ Conclusion ] The combination of TCM and western medicine has better effect than only Clomiphene on dysfunctional ovulatory sterility , it can improve pregnant rate and reduce abortion .

用克罗米酚等促排卵药物，以联合用药方法治疗妇科内分泌功能失调的各种疾病，用药总周期855个，有效排卵率77.4%，妊娠率71.3%，流产率11.9%。

Clomiphene combined with other ovulation-inducing drugs were ured in 228 patients with gynecological endocrinic disorders for 885 cycles , revealing a result of ovulation rate 77.4 % , pregnancy rate 71.3 % and abortion rate 11.9 % .

受孕率明显提高（P<0·01）。[结论]中药能减轻克罗米酚的副反应，改善机体内环境，从而提高受孕率。

The pregnancy rate was much better for the former , P < 0.01.Conclusion Chinese drug can reduce the side effect of Clomiphene , improve the internal environment of the human body , and thus raise the pregnancy rate .

结论：应用补肾活血法能提高排卵率，降低单用克罗米酚而引起的未破裂卵泡黄素化和黄体功能不全的发生率，提高治疗崩漏、闭经和不孕的疗效。

CONCLUSION : Tonifying kidney and activating blood method can improve the ovulation rate , decrease the incidence rate of LUF and LPD caused by only using clomiphene citrate , and improve the curative effect of treating metrorrhagia and metrostaxis , amenorrhoea and infertile .