亲代

结果稳定表达GFP的脉络膜黑色素瘤细胞OCM-1-gfp基本保持了亲代细胞的特征；能在裸鼠体内形成肿瘤并继续生长和转移；

Results Malignant choroidal melanoma cell strain OCM-1 stably expressed GFP and preserved the characteristics of parental generation , OCM-1-gfp may develop melanoma and continue to metastasize in nude mouse .

结论所检测基因突变为亲代遗传，而非个体基因变异；

Conclusion The gene mutations detected were the parental generation , rather than individual genovariation .

耐氟菌株及其亲代菌株ATP酶基因的DNA测序

ATPase Gene DNA Sequence Analysis of Fluoride-Resistant Strains and Their Parent Strains

然而，控制眼睛颜色的基因的DNA序列在白眼亲代和红眼子代中经鉴定是相同的。

However , the DNA sequence for the gene responsible for eye colour was proven to remain the same for white-eyed parents and red-eyed offspring .

6繁殖力指标亲代大鼠高剂量组交配成功率、出生存活率均低于对照组，差异有统计学意义（P0.05）。

The rate of success mating and birth rate in high-dose group were lower than the control group ( P0.05 ) .

9个多态性STR基因座用于完全性葡萄胎的亲代来源鉴定

The Polymorphism of Nine STR Loci on the Genetic Original Identification of Complete Hydatidiform Mole

目的对变型链球菌耐氟菌株及其亲代菌株的胞膜ATP酶基因进行DNA序列分析。

Objective In order to demonstrate the idiotypic variation between fluoride-resistant strains and their pa - rent strains , ATPase gene sequence analysis was carried out .

目的：初步探讨亲代蛋氨酸合酶（MS）基因变异与子代先天性心脏病（CHD）表型的关系。

Objective : To investigate the relations of methionine synthase ( MS ) gene variation in parents with congenital heart disease ( CHD ) phenotype in offspring .

galE变异株及亲代株空肠弯曲菌诱导动物外周神经损伤的对比研究

Comparative study on the role of parent Campylobacter jejuni and galE mutant in inducing experimental peripheral nerve damage

A549－TK细胞对GCV的敏感性是亲代细胞的近100倍。

The sensitivity of A 549-TK cells to GCV was 100 times higher that of parental cells .

弱致病菌株与强致病菌株杂交F1代致病性由弱至强呈连续分布，子代致病性的平均水平接近种亲代致病性的平均值。

Segregation in F1 generations distributed continuously , and the mean of pathogenicity in posterity was close to that in two parents .

方法将亲代BALB/c鼠淋巴细胞经静脉途径输入到（C57BL/6×BALB/c）F1小鼠体内，诱导成狼疮鼠模型。

Methods SLE-like syndrome in ( C57BL / 6 × BALB / c ) F1mice was induced by intravenous injection of lymphocytes from BALB / c parental mice .

就在去年在RSC的科学家们已经开始提供诸如“卵子银行”以确保亲代生育功能的维持。

In just the last year , scientists at RSC have begun offering such " egg banking " to qualified patients for fertility preservation .

变形链球菌耐氟菌株、远缘链球菌耐氟菌株与亲代菌株基因组AP-PCR的比较

The genomic differences between the fluoride-resistant strains of Streptococcus mutans and Streptococcus sobrinus and their parental strains by AP-PCR

体内实验表明GCV能明显抑制转染细胞接种的肿瘤，而亲代细胞接种的肿瘤未受抑制。

In vivo , growth of tumors which formed by transfected cells was significantly inhibited by GCV , however , there was no similar inhibitive effect found in control group .

结论亲代中有COPD患者是子女FEV1（ml）降低和FEV170%pred的独立危险因素，这说明COPD和肺功能受损具有家族聚集倾向

Conclusion Being children of COPD parents is the independent risk factor for lower FEV1 ( ml ) and FEV1 below 70 % pred , which demonstrates the presence of familial aggregation of COPD and pulmonary function impairment

赫尔特发现当果蝇的亲代谢性谷氨酸盐受体基因发生突变时，将通过阻止PI3K的作用来增加神经元的兴奋性。

Howlett found the fruit fly 's metabotropic glutamate receptor ( DmGluRA ) gene , when mutated , increased the excitability of the neuron by preventing PI3K from doing its job .

应用光镜、透射电镜、集落形成试验和MTT法等，检测耐药细胞及其亲代细胞在多西紫杉醇作用后形态学、细胞生长曲线、集落形成能力和生长抑制率的变化；

Light microscope , TEM , colony-forming ability test and MTT assay were used to observe cell morphological changes , colony-forming ability , growth curve and inhibition rate after treatment of A549 / CDDP and A549 cells with docetaxel .

CWDMs对β&内酰胺类抗生素、多粘菌素B、溶菌酶的敏感性显著高于其亲代细菌型及其返祖菌，对毛地黄皂苷敏感；

The CWDMs were higher sensitivities to the β lactam antibiotics , polymyxin and lysozyme than their parental bacteria and the reverts which reverted from the CWDMs re expressed the properties as the parental bacteria .

结论正确的饲养繁殖以及鉴定方法是从亲代杂合子小鼠中获得AQP-1基因敲除纯合子小鼠的有效途径。

Conclusion Appropriate methods for breeding , reproducing , and identifying are the effective way for acquiring AQP-1 knock-out mice from heterozygote mice .

结果亲代人肺腺癌细胞株A549对顺铂的敏感性明显高于耐药细胞株A549/DDP，不同温度加热后A549/DDP细胞对顺铂的敏感性均有提高；

Results Parent human lung adenocarcinoma cell A549 was more sensitive to cisplatin than drug-resistant cell line A549 / DDP . Treated with different temperature , drug sensitivity of A549 / DDP to cisplatin all increased .

[结论]长期低硒、低硒联合低碘会极大降低大鼠发育期机体的GSH-Px活性，其损害在母体内就已发生，子代较亲代损害更重。

[ Conclusion ] Long-term deficiency of Se or both Se and iodine would greatly reduce the GSH-Px activities of rats at the development stage , this had happened in uterus and damaged the offspring generation severely .

方法：①采用细胞计数法绘制亲代A549和A549/DDP细胞生长曲线，四甲基偶氮唑蓝（MTT）法测定A549/DDP对顺铂的耐药指数。

Methods : ① Cell counting was used to plot the cell growth curves of A549 cells and A549 / DDP cells . The resistance index of A549 / DDP cells to cisplatin was measured by tetrazolium ( MTT ) assay .

RHD1227A等位基因为亲代遗传基因，而非个体基因变异。

RHD 1227A allele is an ancestral , but not a spontaneously mutated allele .

动物实验结果显示：mIL－2＋B16细胞的致瘤性明显下降，但体外生长率与其亲代B16细胞相比较无区别。

Experimental results showed that the mIL-2 + B16 cell line did not alter their growth rate compared with its parental B16 cells in vitro , but their ability of tumorigenesis in vivo was reduced .

从转移模型中筛选出高转移胆囊癌细胞亚群GBC-SD／M3，与亲代细胞GBC-SD相比，形态和遗传背景保留一致性，但具有更高转移能力。

Isolated from hepatic metastasis , the line of GBC-SD / M is a subpopulation with high metastatic potential , retaining the histological properties and identification of genetic background of its parent cell line GBC-SD .

按不同比例混合EJ／HyTK细胞和亲代EJ细胞，发现GCV不仅能杀伤转入TK基因的细胞，而且对其周围未转基因的膀胱细胞存在旁观者效应。

When EJ / HyTK cells were mixed with parental EJ cell at various ratios , GCV not only killed EJ / HyTK cells , but neighboring cells without Hy-TK by the bystander killing .

目的：了解两种卵巢癌紫杉醇耐药株（OC3/PIX3及OC3/PIX5）和其亲代细胞紫杉醇敏感株（OC3）染色体DNA拷贝数的差异变化，探讨耐药细胞的分子遗传学改变。

Objective : To investigate the difference of DNA copy number on chromsomes and the molecular genetic alterations among two paclitaxel-resistant ovarian carcinoma cell lines OC_3 / PIX_3 and OC_3 / PIX_5 , and their parent cell line OC_3 which was sensitive to paclitaxel .

但FUdR在临床上表现出较低的口服生物利用度和各种毒副作用。现已证明核苷类药物的糖基化衍生物较之亲代化合物具有更低的毒副作用。

Even though , it suffers from poor oral bioavailability and various side effects in the clinical application . It has been proven that glycosylated derivatives of nucleoside drugs show higher antitumor activity than the parent compounds .

目的分析亲代人内毒素结合肽一级结构，选择可能影响其生物学活性的氨基酸对应碱基位点进行突变，克隆基因突变体mEBP基因并研究其蛋白表达。

Objective To analyze the primary structure of parental human endotoxin binding peptide ( EBP ), induce mutation at base sites corresponding to the amino acids which might influence the biological activity of EBP , clone the mutant of EBP ( mEBP ) and study its expression .