乙酰辅酶

它通过苯丙氨酸降解出乙酰辅酶A和反丁烯二酸。

It is broken down via phenylalanine to give acetyl CoA and fumaric acid .

抑制动力学分析表明，何首乌提取物对FAS的抑制和底物NADPH之间呈非竞争性关系，和丙二酰辅酶A接近竞争性关系，而与乙酰辅酶A为反竞争性关系。

The assay of inhibition kinetics showed that the inhibition to FAS by extract of TFR was non competitive against substrate NADPH , nearly competitive against malonyl CoA and un competitive against acetyl CoA .

乙酰辅酶A羧化酶CT功能域基因的克隆与表达

Clone and Expression of Acetyl CoA Carboxylase CT Domain

乙酰辅酶A羧化酶（ACC）的结构与功能

Structure and Function of Acetyl - CoA Carboxylase

脂肪酸合成酶（fattyacidsynthase，FAS）和乙酰辅酶A羧化酶（acetyl-CoAcarboxylase，ACC）是肝脏组织脂肪酸合成过程中重要的两个酶。

Fatty acid synthase ( FAS ) and acetyl-CoA carboxylase ( ACC ) are two key enzymes during fatty acid synthase in liver tissue .

乙酰辅酶A羧化酶（ACCase）是除草剂的作用靶标之一，此类除草剂主要有两类：芳氧苯氧丙酸类（APP）和环己烯酮类（环己二酮，环己烯二酮，CHD）。

Acetyl-CoA Carboxylase is one of targets acted by herbicides . There are mainly two types of ACCase : aryloxyphenoxypropionates ( AOPP , APP ) and cyclohexanediones ( CHD ) .

乙酰辅酶A羧化酶（Acetyl-CoAcarboxylase，简称ACCase）是植物代谢过程中催化植物脂肪酸合成的关键酶。

Acetyl-CoA Carboxylase ( ACCase ) is the key enzyme that catalyses the plant fatty acid biosynthesis in the plant metabolism .

丙酮酸经过丙酮酸脱氢酶系（乙酰辅酶A羧化酶）催化生成乙酰CoA，乙酰CoA是合成脂肪酸的前体物质，最终进入脂肪酸合成代谢途径。

The pyruvate generate acetyl-CoA through the catalysis of pyruvate dehydrogenase , and acetyl-CoA is the precursor of fatty acid synthesis and ultimately into the fatty acid biosynthesis metabolism pathway .

目的：观察化痰活血方对高脂血症大鼠肝脏过氧化物酶体增殖物激活受体α（PPARα）、乙酰辅酶A氧化酶（ACO）表达的影响。

Objective : To observe effects of Huatan Huoxue Prescription on expressions of peroxisome proliferation substance activating receptor α ( PPAR α) and the target gene acetyl-CoA oxidase ( ACO ) in the liver of the rat with hyperlipemia .

目的：探讨乙酰辅酶A羧化酶抑制剂TOFA对卵巢癌COC1细胞增殖能力的抑制作用及其机制。

Objective : To investigate the influence of TOFA , a Acetyl CoA Carboxylase inhibitor , on cell growth of human ovarian cancer cell line COC1 , and explore the mechanism .

在油脂合成过程中，乙酰辅酶A酰基转移酶（AACT）催化蛋白质的酰基化和去酰基化，而脂肪酸脱饱和酶6（FAD6）则控制油酸脱氢形成亚油酸和亚麻酸等多不饱和脂肪酸。

In the process of the oil combining . AACT is an enzyme that catalyzes the formation of acetoacetyl-CoA from two molecules of acetyl-COA . Fatty acid desaturase catalyze oleic acid into linoleic acid , linolenic acid and by dehydrogenation .

植物乙酰辅酶A羧化酶基因的分子生物学研究进展

Progress of Molecular Biology Research on Plant Acetyl-CoA Carboxylase Gene

乙酰辅酶A羧化酶基因研究综述

Summary of the Gene Research on Acetyl-CoA Carboxylase

然后乙酰辅酶A再进入三羧酸循环为生物体新陈代谢提供能源。

Acetyl CoA into the tricarboxylic acid cycle provides energy for metabolism of organisms .

丙酮酸氧化酶的缺陷同时也导致了6-磷酸葡萄糖脱氢酶和乙酰辅酶A合成酶活力的升高。

The pyruvate oxidase mutation also resulted in the activation of glucose-6-phosphate dehydrogenase and acetyl-CoA synthetase .

乙酰辅酶A羧化酶抑制剂的研究进展

Research Developments on Acetyl-CoA Carboxylase Inhibitors

用这种方式，由两个乙酰辅酶A引进的四个碳，转变成一个四碳二羧酸。

In this fashion the four entering carbons of two acetyl-CoA molecules are conserved to form one 4-carbon dicarboxylic acid .

乙酰辅酶A是物质和能量代谢的重要物质，在体内能源物质代谢中发挥着枢纽性的作用。

As a key substance in material and metabolism , acetyl-coenzyme A plays a central role in energy metabolism in vivo .

其中蛋白质m/z10082.07被鉴定为乙酰辅酶A结合蛋白，其在马兜铃酸肾损害中的作用有待进一步的研究。

The protein at m / z 10082.07 was identified as Acyl-CoA-binding protein whose effects on AA-induced kidney damage need further studies . 4 .

丙酮酸可以通过把葡萄糖转化为碳水化合物，通过乙酰辅酶A转化为脂肪或能量，也可转化为丙氨酸和乙醇。

Pyruvate can be converted to carbohydrates via gluconeogenesis , to fatty acids or energy through acetyl-CoA , to the amino acid alanine and to ethanol .

在我们所试验的浓度下乙酰辅酶A、甘氨酸、葡萄糖-6-磷酸、果糖1-6二磷酸、琥珀酸以及延胡索酸对高粱NADP-苹果酸酶活性无影响。

Acetyl CoA , glycine , G6 P , FDP , succinate and fumarate did not exhibit any effect on the activity of sorghum NADP-malic enzyme .

葡萄糖的这种保护作用可能是由于它能清除细胞内积聚的乙酰辅酶A并能促进细胞内能量物质产生的缘故。

This protective effect of glucose may result from its ability to clear accumulated intracellular Acetyl Coenzyme A and to promote the Production of intracellular energy substances .

大豆种子脂肪酸合成主要发生在质体中，参与脂肪酸合成的酶主要为乙酰辅酶A羧化酶和脂肪酸合酶。

Fatty acid biosynthesis in soybean seed takes place in plastids . A number of enzymes are involved in this synthesis such as acetyl-CoA carboxylase ( ACCase ), fatty acid synthase complex ( FAS ) and etc.

利用该模型可以解得比碳源消耗速率、比生长速率、比乙酰辅酶A生成速率、比氧消耗速率等关键的反应速率。

Based on the model , the metabolic bioreaction rates such as the specific substrate consumption rate , the specific growth rate , the specific acetyl-CoA formation rate as well as the specific oxygen uptake rate are obtained .

研究表明：SCOT催化乙酰乙酰辅酶A生成的具体机制是与辅酶A的巯基生成硫酯并以非共价键的形式连接辅酶A的ADP基团。

Elegant studies revealed that , the special mechanism of SCOT catalyzing the formation of acetoacetyl CoA is generating the thioester with coenzyme A and binding the ADP groups of coenzyme A in the form of non – covalent bond .

臭味假单胞菌乙酰乙酰辅酶A硫解酶的提纯及性质研究

Purification and Properties of Acetoacetyl-Coenzyme A Thiolase From Pseudomonas Putida

磷酸转乙酰化酶对辅酶A效价测定的影响

Influence of phosphotransacetylase on potency determination of coenzyme A

在这些肝外组织的线粒体中，SCOT蛋白催化反应生成乙酰乙酰CoA，乙酰乙酰CoA经硫解酶转化生成乙酰辅酶A。

In the extrahepatic tissue mitochondria , SCOT catalytic reaction to generate acetyl CoA , acetyl acetyl CoA by sulfur solution enzyme into acetyl CoA .