髓系祖细胞
- 网络myeloid progenitor;myeloid progenitor cell;Meloid progenitor
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野生型的WT1转染髓系祖细胞后,可使细胞失去受粒细胞集落刺激因子的诱导分化,而代之以持续增殖。
Constitutive WT1 expression in myeloid progenitor cells by the transfection of the wild-type WT1 gene promoted their proliferative response to G-CSF , but inhibited their differentiation .
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1,4-苯醌对IFN-γ不同基因型髓系祖细胞集落生长影响的研究
Effect of 1,4-Benzoquinone on Growth of Hematopoietic Myeloid Progenitor Cells with IFN - γ Different Genotypes
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瘦素(Leptin)是由脂肪细胞分泌的一种细胞因子,可以刺激髓系祖细胞增殖。
Leptin is a regulator of fat metabolism that is synthesized in adipocytes , and was shown to stimulate myeloid proliferation .
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既往研究发现:APS是当归中促进造血的有效成分,APS对正常或贫血小鼠的髓系造血祖细胞(BFU-E、CFU-E、CFU-GM和CFU-MK)的增殖分化有显著的促进作用;
The past researches discovered that APS could obviously promote the proliferation and differentiation of BFU-E , CFU-E , CFU-GM and CFU-MK in health and anaemic mice .
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结果:APS在体外可促进髓系多向造血祖细胞CFUGEMM增殖分化;APS诱导制备的骨髓基质细胞、内皮细胞、单核细胞培养上清液富含造血生长因子活性;
Results : APS and the conditioned media of bone marrow stromal cell ( BMSC ), endothelial cell ( Ec ), monocyte ( Mc ) induced by APS markedly promoted the proliferation and differentiation of early multipotential progenitor cell ( CFU GEMM );
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当归多糖对人髓系多向造血祖细胞增殖分化的影响及其机理研究
Study on biological mechanism of angelica polysaccharide regulation on human early multipotential progenitor cell