非典型抗精神病药

资料综合：有确凿的证据提示非典型抗精神病药能改善精神分裂症认知功能；

DATA SYNTHESIS : There was irrefutable evidence suggested that atypical antipsychotics could improve the cognitive function of schizophrenia .

结论：催乳素水平不能说明精神分裂症发病及严重程度，也不能作为非典型抗精神病药疗效的指标。

Conclusion : Neither can the serum prolactin levels explain the pathogenesis and severity of schizophrenia , nor predict the clinical outcome of atypical antipsychotics .

目的探讨非典型抗精神病药利培酮对首发精神分裂症患者血浆催乳素（PRL）水平的影响及其与疗效的关系。

Objective To investigate the effect of atypical antipsychotic drug risperidone on the plasma prolactin level and their relationship with clinical efficacy .

结果：四种非典型抗精神病药治疗后，患者TG水平明显升高，治疗后8周较4周更显著（P<0.01），HDL水平明显降低（P<0.05或0.01）；

Results : After treatment , TG levels were increased significantly ( P < 0.05 ), especially at the end of 8th week ( P < 0.01 ), but HDL levels decreaded ( P < 0.05 or 0.01 );

典型与非典型抗精神病药对首发精神分裂症P50感觉门控的作用

On the Spirit of the Fight against SARS and the Moral Education of the College Students ; The effects of typical and atypical antipsychotics on P50 sensory gating in first-episode schizophrenics

国外研究报道非典型抗精神病药奥氮平可增加健康受试者的睡眠连续性和慢波睡眠，并用于增加对SSRI类药物治疗效果不理想患者的疗效。

The atypical antipsychotic drug olanzapine which can increases sleep continuity and enhances slow wave sleep ( SWS ) in healthy subjects , has been employed as an augmentation treatment in depressed patients unresponsive to treatment with selective serotonin reuptake inhibitors ( SSRIs ) .

哌罗匹隆是一种安全有效的非典型抗精神病药。

Perospirone is an effective and safe atypical antipsychotic drug .

非典型抗精神病药对精神分裂症患者血脂影响的对比研究

The Effect of Atypical Antipsychotics on Blood-Lipid Metabolism of Patients with Schizophrenia

结论：典型与非典型抗精神病药均引起体重增加，其中对体重影响从小到大为：维思通<舒必利<氯氮平<氯丙嗪。

Conclusion : Both conventional and newer antipsychotics were associated with weight gain .

非典型抗精神病药对难治性抑郁症的治疗作用

Therapeutic effect of atypical antipsychotics on treatment-refractory depression

降糖药联合行为干预治疗非典型抗精神病药所致代谢综合征的研究

Efficacy of behavioral intervention therapy and metformin in the treatment of atypical antipsychotics-induced metabolic syndrome

但是跟所有的药物一样，非典型抗精神病药有自己的风险和副作用。

However , like all medications , atypical antipsychotics have their own set of risks and side effects .

3种非典型抗精神病药对精神分裂症患者精神症状和生活质量的影响

Comparative Study on the Psychopathology and the Quality of Life of Schizophrenia Treated with Risperidone , Clozapine and Quetiapine

非典型抗精神病药对男性精神分裂症患者性功能影响的初步分析抗抑郁药：在精神病科用于缓解抑郁症的药物。

Atypical antipsychotics on sexual function in male patients with schizophrenia Antidepressant : Any drug used to treat depression .

结果：非典型抗精神病药氯氮平引起的脑电改变主要是慢波增多，典型抗精神病药氯丙嗪引起的脑电改变主要是α波失律。

Results : Clozapine increased mainly slow wave in EEG of the patients , while chlorpromazine caused mainly irregularity of α wave .

对新型非典型抗精神病药帕利哌酮、伊洛哌酮和阿塞那平的作用机制、药动学、临床应用、药物相互作用及不良反应等进行简要介绍。

The mechanism of action , pharmacokinetics , clinical application , drug interactions , and adverse reactions of new atypical antipsychotics paliperidone , iloperidone , and asenapine were reviewed .

结论国内精神分裂症药物处方方式逐渐以非典型抗精神病药占主流，经济负担和患者的症状？

Conclusion Atypical drugs are gradually the major to treat schizophrenia in China , and the antipsychotic drug use patterns are greatly affected by the economic burden and clinical profile of patients .

目的：系统论述非典型抗精神病药治疗精神分裂症临床研究和应用的进展，评价其临床疗效和安全性。

OBJECTIVE : To systematically review the aspects of clinical usage and research progress of atypical antipsychotics in the treatment of schizophrenia ( SP ) and evaluate their clinical efficacy and safety .

妊高征孕妇血清催乳素及尿酸水平测定分析四种非典型抗精神病药对血清催乳素和血脂的影响

Examination and Analysis of Serum Prolactin and Uric Acid in Pregnancy Induced Hypertension ; Effecs of four kinds of atypical antipsychotic drugs on the blood lipids and prolactin level in patients with schizophrenia

抗精神病药不良反应发生率为16.0%，典型抗精神病药发生率（18.4%）显著高于非典型抗精神病药（9.6%）。

The total rate of adverse drug reactions of antipsychotic drugs was 16.0 % , the incidence of typical antipsychotic drugs ( 18.4 % ) was higher than that of atypical antipsychotic drugs ( 9.6 % ) .

结论：非典型抗精神病药氯氮平与典型抗精神病药氯丙嗪对首发精神分裂症患者脑电图的影响方式和作用强度是不同的，氯氮平的影响大于氯丙嗪。

Conclusions : Non-classical antipsychotic ( clozapine ) and classical antipsychotic ( chlorpromazine ) have different pattern and intensity of influence on EEG of first episode schizophrenia . The influence of clozapine was larger than that of chlorpromazine .

结论：丙戊酸钠缓释剂德巴金可以协助治疗精神分裂症以及分裂情感障碍的兴奋状态齐拉西酮是一种安全、有效的非典型性抗精神病药，用于治疗精神分裂症和分裂情感性障碍。

Conclusion : Depakine can be used for the supplementary therapy of excitement state in patients with schizophrenia and schizoaffective disorder . Ziprasidone is a safe and effective drug for the schizophrenia and schizoaffective disorder .

结论非典型和典型抗精神病药对精神分裂症免疫应答产生一定程度的抑制作用，两者之间无明显差异；

Conclusions Typical and atypical antipsychotic medications may inhibit the immune response in schizophrenia to some extent , but there was no significant difference between them .