雷帕霉素

雷帕霉素通过抑制淋巴细胞增殖保护由conA诱导的肝脏损伤

Rapamycin Prevents Con A-induced Liver Injury by Inhibiting Lymphocyte Proliferation

ERK1/2在IgA肾病大鼠肾脏中的表达及雷帕霉素对其影响

Expression of ERK1 / 2 in IgA Nephropathy Rats and Effects of Rapamycin

EXCEL雷帕霉素药物洗脱支架临床应用安全性及近期疗效评价

The clinical safety and short-term therapeutic efficacy of EXCEL drug-eluting stent

HPLC测定雷帕霉素聚乳酸-聚乙醇酸纳米粒的包封率

Determination of Encapsulation Efficiency of Rapamycin-loaded Poly ( lactic-co-glycolic ) acid Nanoparticles by HPLC

国产雷帕霉素洗脱支架在急性ST段抬高型心肌梗死中的应用

Clinical use of domestic sirolimus-eluting stents in the treatment of acute ST-elevation myocardial infarction

目的评价国产EXCEL雷帕霉素药物洗脱支架临床应用的安全性及疗效。

Objective To evaluate the clinical efficacy and safety of EXCEL drug-eluting stents .

冠心病患者应用可降解涂层雷帕霉素洗脱支架与PARTNER支架的随机对照研究

A Randomized Comparison between Biodegradable Polymer Sirolimus-Eluting Stents and PARTNER Stents for Patients with Coronary Artery Diseases

雷帕霉素在顺铂诱导HeLa细胞凋亡中的协同作用

Synergistic augmentation of cisplatin-induced apoptosis in HeLa cells by rapamycin

急性冠脉综合征患者药物洗脱支架雷帕霉素Cypher~（TM）植入后的不良反应分析

Analysis of Adverse Reactions of Cypher Drug Eluting Stent Implantation in Treatment of Acute Coronary Syndrome

雷帕霉素药物涂层支架（CYPHER~（TM））治疗前降支长病变的临床研究

The clinical study of CYPHER ~ ( TM ) stent in long lesion of left anterior descending artery

雷帕霉素和中药百令胶囊对大鼠小肠移植后细胞凋亡和FaslmRNA表达作用

Effect of RAPA and Bailing Capsule on Apoptosis and Expression of FasL mRNA on Small Bowell Transplantation of Rats

目前临床常用的有雷帕霉素（Rapamycin）洗脱支架和紫杉醇（paclitaxel）洗脱支架，但药物洗脱支架的使用也面临许多问题，如远期效果、价格昂贵等。

Rapamycin-eluting stent and paclitaxel-eluting stent are used frequently in clinic .

结论：雷帕霉素洗脱支架和紫杉醇涂层支架治疗CAD合并2型DM的患者有相似的疗效。

Conclusion : The efficacy of rapamycin eluting and paclitaxel eluting stent were similar in coronary heart disease patients with type 2 diabetes .

目前临床上应用的药物涂层支架主要有雷帕霉素涂层支架和紫杉醇涂层支架，即CYPHER支架和TAXUS支架。

Now DES used on clinic are CYPHER stent and TAXUS stent .

免疫抑制剂雷帕霉素对LPS免疫激发大鼠脑内免疫相关核团神经元Fos和nNOS表达的影响

Effect of rapamycin on Fos and nNOS expression in the immunity correlative neurons challenged with lipopolysaccharide in rat

雷帕霉素联合5-脱氧氮杂胞苷干预乳腺癌MCF-7细胞株体外培养效应

The influence of rapamycin combined with 5-Aza-cdR to interfere in the in vitro culture of MCF-7 cell line

雷帕霉素对人前列腺癌PC-3细胞的作用及其机制

Effects of rapamycin on prostate cancer PC-3 cells

国产雷帕霉素对小鼠淋巴细胞增殖和DTH、GVHR的免疫抑制作用

The immunosuppressive effect of rapamycin on lymphocytic proliferation and DTH 、 GVHR

目的研究雷帕霉素对小鼠T淋巴细胞体外的增殖、白细胞介素2（IL-2）表达及细胞周期的影响。

Objective To investigate the effects of rapamycin on proliferation , levels of interleukin-2 ( IL-2 ) and cell-cycle of mouse T lymphocytes in vitro .

雷帕霉素对柯萨奇病毒B3诱导的大鼠心肌细胞Ⅰ型胶原表达的调控

Effects of rapamycin on collagen type ⅰ expression in rat myocardial cell induced by CVB 3

雷帕霉素对人肝癌细胞BEL-7402体外抗肿瘤作用研究

The Studies of Antitumor Effect of Rapamycin on Human Hepatocellular Carcinoma BEL - 7402 Cells in vitro

结论雷帕霉素能减轻PAN肾病小鼠蛋白尿的程度，作用机制可能与下调肾小球VEGF及其受体基因表达有关。

Conclusion Rapamycin can reduce the proteinuria of PAN nephritic mice , and the mechanism may be related to the down-regulation of expression of VEGF and VEGFR of glomeruli .

结论雷帕霉素降低EPCs的数量、增殖能力、迁移能力、黏附能力和体外血管形成能力，并呈浓度和时间依赖性。

Conclusion Rapamycin decreases the number , proliferative , migratory , adhesive and in vitro vasculogenesis capacity of EPCs .

雷帕霉素抑制胆囊癌GBC-SD细胞的生长和转移

Rapamycin inhibits growth and metastasis of gallbladder cancer GBC-SD cells

雷帕霉素药物洗脱支架Firebird与Cypher的临床对比研究

Clinical contrast investigation of Firebird and Cypher rapamycin eluting stent

目的：观察Cypher雷帕霉素药物洗脱支架在急性ST段抬高心肌梗死（ASTEMI）中的临床研究。

Objective : To investigate the clinical study of cypher drug-eluting stent in patients with acute ST - segment elevation myocardial infarction .

目的开发研制国产雷帕霉素（Rapamycin，RPM），探讨其免疫抑制作用机理。

Objective To manufacture rapamycin ( RPM ) a new type immunosuppressant made in our country and investigate its immunosuppressive mechanism .

新型免疫抑制剂效果强，副作用小，已倍受重视，例如他克莫司（FK506）、雷帕霉素（rapamycin，RAP）都是研发的热点。

The neotype immunity inhibitors had the better effect of treatment , and little side effect , such as FK506 , rapamycin .

背景：载雷帕霉素（Rapamycin）可降解聚合物涂层支架（商品名EXCEL）是使用与目前的药物洗脱支架（DES）不同的聚合物和药物涂层技术制成的新型药物涂层支架。

Backgroud : " EXCEL " is a new kind of stent with rapamycin-coated and biodegradable polymer , different from the current drug-eluting stent ( DES ) .

裸BES与涂层BES径向支撑力相似，略高于雷帕霉素BES。

The naked BES showed similar radial strength to coated BES , both of which were slightly higher than that of sirolimus-eluting BES .