阿奇霉素

蒙脱石散与维生素B6联合应用减轻阿奇霉素胃肠道不良反应的临床随机对照研究

Montmorillonite Powder Combined with Vitamin B_6 for Azithromycin-induced Adverse Reactions of Gastrointestinal Tract : Clinical Randomized Control Trials

复方阿奇霉素葡萄糖注射液中阿奇霉素的HPLC测定

Determination of Azithromycin in Compound Azithromycin and Glucose Injection by HPLC

HPLC法测定注射用门冬氨酸阿奇霉素的含量和有关物质

Determination of azithromycin aspartate for injection and its related substances by HPLC

结论阿奇霉素治疗CAP的方案优于头孢唑林。

Conclusion Azithromycin treatment scheme is better than the CAP cefazolin .

HPLC法测定阿奇霉素糖浆剂中阿奇霉素的含量

Determination of azithromycin in azithromycin syrup by HPLC

用HPLC法测定乳糖酸阿奇霉素注射液的含量

Determination of Azithromycin Lactobionate Injection by HPLC

漫反射FT-IR法测定阿奇霉素片剂中阿奇霉素的含量

Determination of azithromycin in the azithromycin tablets by diffuse reflectance FT-IR

RP-HPLC法测定注射用阿奇霉素有关物质

Determination of related substances in azithromycin injection by RP-HPLC

目的：测定冠心病患者外周血单核细胞中肺炎衣原体（Cpn）DNA，对DNA阳性患者予阿奇霉素治疗，探讨肺炎衣原体感染与冠心病的相关性。

Objective : To study the association between infection with chlamydia pneumoniae ( Cpn ) and coronary heart disease ( CHD ) .

目的建立注射用门冬氨酸阿奇霉素中阿奇霉素的含量和有关物质测定的HPLC法。

Objective To establish an HPLC method for the determination of azithromycin and its ( related ) substances in azithromycin aspartate for injection .

目的：评价阿奇霉素序贯治疗儿童社区获得性肺炎（CAP）的疗效及成本。

Objective : To : investigate the curative effects and cost of sequential treatment of children community acquired pneumonia ( CAP ) with azithromycin .

口服阿奇霉素治疗抑制IL10、IFNγmRNA在大鼠肺损伤模型中的表达；

The oral administration of AZI inhibited the expression of IL 10 and IFN γ mRNA ;

ELF的阿奇霉素浓度按尿素稀释法算出。

The concentration of azithromycin in ELF determined by means of the urea dilution method .

方法：30例患儿应用阿奇霉素10mg/（kg·d），每日口服1次，连用3天，观察7～10天。

METHODS : Thirty children patients were treated with azithromycin 10mg / ( kg · d ), po , qd × 3d and observed 7 - 10 days .

目的：测定急性冠脉综合征（ACS）患者阿奇霉素治疗前后血肺炎衣原体（Cpn）DNA及IgG抗体滴度，探讨肺炎衣原体感染与ACS发生的相关关系。

Objective : To investigate the correlation between infection with chlamydia pneumoniae ( Cpn ) and acute coronary syndrome ( ACS ) .

目的：检测国产磷酸阿奇霉素（Azithromycin）以及对照乳糖酸红霉素对临床分离致病菌的体外抗菌作用。

Objective : To investigate the antibacterial activity in vitro of domestic Azithromycin phosphate and compare with erythromycin lactobionate .

阿奇霉素（Azithromycin，ATM）是新一代的大环内酯抗生素，它与传统的红霉素相比有许多优点。

Azithromycin ( ATM ) is one of the new generation of macrolides and has several advantages over traditional macrolides such as erythromycin .

阿奇霉素对ICU老年下呼吸道多药耐药铜绿假单胞菌感染的前瞻研究

A prospective controlled study of azithromycin on lower respiratory tract infections caused by multi-drug resistant pseudomonas aeruginosa in the elderly in intensive care unit

结果：1.左氧氟沙星组与阿奇霉素组的有效率分别为93.3%和83.3%，痊愈率分别为82.2%和67.4%，差异均有统计学意义（p0.05）。

The effective rate of levofloxacin group and azithromycin group were 93.3 % and 83.3 % respectively , and the differences between two groups were statistical significance ( p0.05 ) .

阿奇霉素可作为治疗DPB首选药物。

Azithromycin could be used as the first drug for the treatment of DPB .

目的：观察兰索拉唑、阿奇霉素和甲硝唑短程低剂量三联疗法根除幽门螺杆菌（Hp）的临床疗效和治疗费用。

AIM : To observe the effect and therapy cost of short-term low-dose triple therapy with azithromycin , metronidazole and lansoprazole for the eradication of Helicobacter pylori ( Hp ) .

试验组与对照组各对应指标差异无统计学意义（P0.05）。体外抗菌活性研究结果表明，托氟沙星的抗菌活性与司帕沙星、氧氟沙星、环丙沙星相似，对革兰氏阳性菌的抗菌活性明显优于阿奇霉素。

The results of in vitro susceptibility test showed that tosufloxacin possess similar antibacterial activity to sparfloxacin , ofloxacin and ciprofloxacin , and is more active against gram positive cocci than azithromycin .

方法：门诊治疗144例患者，试验组（A组）50例OC膜剂阴道给药，并口服阿奇霉素；

METHODS : The test group A of 50 cases were given OC films in genital duct and Azithromycin Granules in oral administration .

同样浓度的阿霉素作用相同时间后，A549、A549／ADM和使用阿奇霉素处理后的A549／ADM的荧光强度分别为121.4、51.2、96。

With the same treatment , the fluorescence intensities in A549 , A549 / ADM and A549 / ADM were 121.4 , 51.2 and 96 respectively .

目的：观察静脉滴注阿奇霉素治疗非淋菌性泌尿生殖道炎（NGU）的临床效果。

AIM : To observe the clinical therapeutic effect of intravenous drip azithromycin in treating nongonococal urethritis ( NGU ) .

UU对10种药物敏感性最高的是交沙霉毒（99.0%），其次是阿奇霉素（95.9%）。

The highest susceptibility rate of UU to ten kinds of antimicrobial agents was Jos ( 99 % ), the second was Azi ( 95 . % ) .

目的：建立高效液相-质谱法（HPLC-MS）测定人血浆中阿奇霉素的浓度，用于研究阿奇霉素片的人体药动学。

Objective : To develop a HPLC-MS method for determining azithromycin in human plasma , and to investigate pharmacokinetics of azithromycin in healthy volunteers .

结果设计合成了3个新的阿奇霉素衍生物和两个新中间体，目的物4a，4b，5经波谱分析结构准确。

RESULTS Three new azithromycin derivatives and two intermediates were synthesized . Target compounds 4a , 4b and 5 are confirmed to be correct by spectrum analysis .

UU对环丙沙星、氧氟沙星、红霉素、阿奇霉素的耐药率分别是68.29%、48.29%、24.63%、21.46%。

The resistance rates of the tested mycoplasma against ciprofloxacin , ofloxacin , erythromycin and azithromycin were 68.29 % , 48.29 % , 24.63 % and 21.46 % , respectively .

治疗后阿奇霉素组FEV1.0、FEV1.0/FVC均高于常规治疗组，差异有显著性（P0.01）。

FEV1.0 and FEV1.0/ FEV of Azithromycin therapy group is higher than routine therapy group significantly ( P0.05 ) .