阴性症状

文拉法辛辅助治疗精神分裂症阴性症状Meta分析

Meta-analysis of venlafaxine combined with antipsychotics in treating negative symptoms of schizophrenia

结论：临床症状改善与IgG水平相关，且以阴性症状为主。

Conclusion : The degree of clinical improvement , mainly in negative symptoms , is related to the level of IgG .

阿立哌唑与氯氮平治疗精神分裂症阴性症状对照研究的Meta分析

Meta-analysis of comparative study in treatment of negative symptom between aripiprazole and clozapine

结果：阳性症状精神分裂症患者血清一氧化氮明显高于正常组（P＜0.01），阴性症状精神分裂症患者血清一氧化氮含量明显低于正常组（P＜0.01）。

Results : The serum nitric oxide level of type ⅰ schizophrenia was significantly higher , while type ⅱ lower than normal controls ( both P < 0 01 ) .

以阳性与阴性症状量表（PANSS）及不良反应量表（TESS）评定症状、疗效和安全性。

Symptoms , efficacy and security were rated with the PANSS and TESS .

同时，对病人进行阳性和阴性症状评定量表（PANSS）测查。

The positive and negative symptoms were measured with the PANSS and SANS .

背景5-羟色胺2A受体基因已经证实为精神分裂症的候选易感基因，因为阐明其作为非典型抗精神病药物重要作用靶点减轻阴性症状已引起业界倍加关注。

Background 5-hydroxytryptamine 2A receptor ( 5-HT2A ) gene has been regarded as a candidate gene for susceptibility to schizophrenia .

并用阳性和阴性症状量表（PANSS）评定患者的精神症状。

Psychiatric symptoms were assessed by Positive and Negative Syndrome Scale ( PANSS ) .

TD组阴性症状综合评价总分明显高于非TD组；

The total score of multiple evaluation in TD group was obviously higher than that in the non - TD group ;

阴性症状组患者IL-6水平明显高于阳性症状组和正常对照组，而其IL-10水平则低于阳性症状组；

IL-6 was significantly higher in negative symptom subgroup compared with positive subgroup and controls , while IL-10 was lower in negative subgroup than in positive ones .

用阳性与阴性症状量表（PANSS）于治疗前后对症状严重程度进行评定。

Positive and negative symptoms scale ( PANSS ) were used to evaluate the severity of the symptoms .

方法：应用Meta分析对34项研究奎硫平与其他抗精神病药治疗精神分裂症阴性症状文献进行再分析，评价其合并效应量的大小和综合显著性差异。

Method : 34 studies that compare effects differences in treatment of negative symptom between quetiapine and other antipsychotics were analysised by meta-analysis in effect side and comprehensive .

精神分裂症患者的虚假记忆指标与PANSS总分、阴性症状、阳性症状以及妄想症状、幻觉症状无显著相关性。

The indexes of false memory had no significant correlation to the factors of delusion and hallucination of PANSS .

方法应用Meta分析对22项研究维思通与其它抗精神病药物治疗精神分裂症阴性症状进行再分析，评价其综合显著性差异和效应大小。

Methods 22 studies that compare effects differences in treatment of negative symptom between risperidone and other antipsychotics was analysed by meta analysis in comprehensive test and effect side .

受教育程度、阴性症状和PANSS总分与认知功能有显著的相关性。

Total score of educational level , negative symptoms , the score of PANSS has significant correlation with cognitive function .

结果：A组第8周末阳性和阴性症状量表（PANSS）总分和各项目积分比疗前均显著下降（P均<0.001）；

Results : The total scores and all factor scores of the positive and negative symptom scale ( PANSS ) in group A after 8 weeks decreased significantly ( P < 0.001 ) .

分别于入院时和康复训练12周末，采用住院患者护士观察量表（NOSIE）、阴性症状评定量表（SANS）、日常生活能力量表（ADL）对每位患者进行评定。

To evaluate the results for every patients that when they hospitalization and12 weeks after rehabilitation training by NOSIE , SANS and ADL .

方法：对精神分裂症患者进行大脑透明隔区CT扫描，以阳性与阴性症状量表（PANSS）评定精神症状。

Method : Schizophrenic patients were scanned by computerized tomography ( CT ) on brain area of pellucid septum and their psychotic symptoms were evaluated by positive and negative syndrome scale ( PANSS ) .

采用阳性症状和阴性症状量表（PANSS）评定临床疗效，不良反应量表（TESS）评定不良反应。

The positive and negative syndrome scale ( PANSS ) and treatment emergent symptoms scale ( TESS ) were used to evaluate curative effect and untoward reaction .

采用简明精神病量表（BPRS）、阳性和阴性症状量表（PANSS）进行评价。

Brief psychiatric Rating Scale ( BPRS ) and Positive And Negative Syndrome Scale ( PANSS ) were used to assess the effects .

结论精神分裂症患者发病期血清CPK活性明显增高，而阴性症状为主要症状的患者和阳性症状为主要症状的患者间存在差异性；

Conclusion The activity of serum CPK increases clearly during onset period in schizophrenics , and there was a difference between patients with positive and negative symptoms ;

阴性症状组的双侧脑室前角距/颅内板距比（BFR）较阳性症状组为大。

The bifrontal ratio ( BFR ) score in negative symptoms group was larger than that in positive symptoms group .

采用阴性症状量表（SANS）和阳性症状量表（SAPS）评价患者的精神病性症状的疗效。

The efficacy was measured by Scale for the Assessment of Negative Symptoms ( SANS ) and Scale for Assessment of Positive Symptoms ( SAPS ) .

于治疗前后采用阴性症状评定量表（SANS），护士用住院患者观察量表（NOSIE）进行评定。

They were assessed by scale for assessment of negative symptoms ( SANS ) and nurses ' observation scale for inpatient evaluation ( NOSIE ) .

两组均以阴性症状量表（SANS）、阳性症状量表（SAPS）、简明精神病症状量表（BPRS）和副反应量表（TESS）进行盲式评分。

Both were double-blindly assessed with the SAPS , SANS , BPRS and TESS , before and after treatment , to evaluate the effects on positive and negative symptoms .

目的探讨具有暴力行为的分裂症患者阳性症状、阴性症状评定量表（PANSS）的相关特征，为预防减少分裂症患者暴力行为提供依据。

Objective To explore the relation character of schizophrenics with an act of violence in PANSS evaluation and afford a foundation for decreasing the violence of schizophrenics .

应用阳性与阴性症状量表（PANSS）、生活质量综合评定问卷（GQOLI-74）分别于治疗前后评估患者的生活质量与疗效。

The quality of life and curative effect 's were assessed with the GQOLI-74 and PANSS before and after treatment respectively .

在治疗前、治疗第4,8,12周末以阳性和阴性症状量表（PANSS）总分减分率、阴性因子分减分率和不良反应量表（TESS）评定疗效和不良反应。

Effects and side effects were assessed with the Positive and Negative Syndrome Scale ( PANSS ) and Treatment Emergent Symptoms Scale ( TESS ) respectively before and after 4,8,12 week treatment .

N2潜伏期和波幅与PANSS阳性症状分呈负相关，而WCST总错误数与PANSS总分和阴性症状总分正相关。

Latency and amplitude of N2 negatively correlated with scores for positive symptoms , total errors in WCST positively related with PANSS total scores and scores for negative symptoms .

本研究结果提示精神分裂症前额叶背外侧目存在谷氨酸能低下，另外海马内也有QU－Gin下降的·2·趋势，而且前额叶谷氨酸能低下与认知功能损害和BPRS阴性症状总分相关。

The results of this study show the dysfunction of glutamate in dorsolateral prefrontal cortex and the relationship between the decreased of NMDA - glutamatergic function and cognitive deficits and some negative syndromes .