锌酶

所以，要把二氧化碳由肺部排出我们体外，这种含锌酶至关重要。

So this zinc enzyme is critical for getting CO2 out of our bodies through the lungs .

发现了进入多核锌酶活性中心位点的外加金属离子随pH值变化在不同位点之间的迁移现象。

Through these works , we have expanded the investigation range of the direct interaction and found the transformation phenomena of metal ions in different active sites with varied pH values .

该酶的金属离子为铜锌，酶活约为5.76U/mL。

The metal ion of the SOD was Cu and Zn .

碳酸酐酶是催化二氧化碳的可逆水合反应的一种含锌金属酶。

Carbonic anhydrase ( CA ; EC 4.2.1.1 ) is a zinc-containing metalloenzyme that catalyzes the reversible conversion of CO_2 to bicarbonate .

目前正对HIV感染者进行锌指核酸酶临床实验，利用这种酶删除一段使病毒进入免疫细胞的基因。

Clinical trials are underway in HIV patients of zinc-finger nucleases that remove a gene that allows the virus to enter immune cells .

锌指核酸酶是一种人工制做限制性内切酶，通过将锌指DNA结合区与限制性内切酶的DNA切割区融合获得。

Zinc finger nucleases ( ZFNs ) are artificial restriction enzymes made by fusing an engineered zinc finger DNA-binding domain to the DNA cleavage domain of a restriction enzyme .

然而，由于目前在实验上很多锌指核酸酶的晶体结构很难得到，这样就限制了锌指核酸酶和DNA相互作用的理论研究。

However , since crystal structure of the zinc finger nuclease has not been obtained in experiments , theoretical studies on interactions of zinc finger nuclease with DNA remain very limited .

他采用一种名为“锌指核酸酶”的蛋白质（即锌指蛋白），来剥离T细胞表层的CCR5基因。

He used a " zinc finger nuclease " Protein ( zinc finger protein ), stripping to T-cell surface of the CCR5 gene .

利用人工锌指核酸酶（ZFN）进行基因敲除，简单高效，成为了近年来的研究热点。

Using zinc finger nucleases ( ZFN ) for gene knockout is very simple and efficient , and has become a hot research field in recent years .

Sangamo公司最新型的药采用一种锌指核酸酶来治疗糖尿病性神经病变，一种常见的由糖尿病引发的神经损害和神经痛。

The most advanced of Sangamo 's drugs uses a zinc-finger nuclease to treat diabetic neuropathy , a common complication of diabetes that causes nerve damage and pain .

为了解决这个问题，我们拟建立更加简单高效的利用ZFN的基因敲除技术，我们将这种技术称作为睾丸介导人工锌指核酸酶（TM-ZFN）的基因敲除技术。

To solve this problem , we intend to establish a more convenient method of gene knockout technology using ZFN , which is referred as testis-mediated zinc finger nucleases ( TM-ZFN ) gene knockout technology .

铜锌金属天然酶活性中心量子化学计算

Quantum Chemistry Calculation of the Copper and Zinc Active Site of Natural Enzyme

污泥中锌对土壤酶活性的影响及评价

Quantitative assessment of the effect of zinc on enzyme activity in biosolids-amended soils

锌指核酸酶在基因组靶向修饰中的应用

Application of Zinc Finger Nucleases in Genome Targeting Modification

他还补充说锌指核酸酶可能对一些基因具有不可预知的作用。

He adds that the zinc finger nucleases could have unpredictable effects on several genes .

模块拼装是一个快速，便捷，开放源码的锌指核酸酶合成方法。

Modular assembly is a rapid , convenient and open-source method for the synthesis of ZFNs .

相比之下，锌指核酸酶特异性要强很多，但仍可能产生一些意料外的改变。

Zinc-finger nucleases are far more specific , but they still have the potential to make unwanted changes .

美国科学家已经在人类身上进行了类似的实验，并取得了一些成功，他们使用了一种更古老的被称为锌指核酸酶技术的基因编辑工具。

American scientists have carried out similar experiments on humans , with some success , using an older gene editing tool called zinc finger nuclease .

过去研究人员通过定位这种酶在基因组中的结合位点，之后检测这些序列是否受损的方法来寻找锌指核酸酶的错误。

In the past , researchers have looked for zinc-finger nuclease errors by assaying where in the genome the enzymes might bind , and checking to see whether those sequences were broken .

使用分子信标作为S1核酸酶的底物，通过检测不同锌离子浓度下酶切初速度的变化，实现了对锌离子简便、快速的检测。

Molecular beacon was employed as the substrate . By monitoring the initial velocity change of S1 nuclease with different zinc concentrations , zinc detection could be achieved .

可见吸收光谱法研究铜锌超氧歧化酶活性中心金属离子与氯化钴的相互作用

Study on the interaction of metal ion in active center of superoxide dismutase with cobalt chloride by visible spectroscopy

采用样板荧光底物法测定了锌离子对肽酶和碱性磷酸酶活性的影响。结果表明：锌离子对两种酶活性均有双重作用。

The effect of Zn2 + on extracellular enzymatic activities was measured by using the method of model fluorescent substrates .

从上述研究结果，可以认为含锌氨基酰化酶的活性部位也具有相对的柔性。

The above results suggest that the active sites of metal enzyme containing Zn ￣ 2 + also are more flexible conformationally than the whole enzyme .

这些酶名为锌脂蛋白核算酶，可在实验室内加工后靶向作用于特定基因，引入序列改变，获得希望得到的特性。

The enzymes known as zinc finger nucleases can be engineered in the lab to target specific genes , introducing changes known to cause the desired trait .

光谱法研究铜锌超氧歧化酶与组氨酸钴（Ⅱ）的相互作用Ⅱ.外加组氨酸钴（Ⅱ）及磷酸盐的影响

Study on the Interaction of Copper Zinc Superoxide Dismutase with Cobalt (ⅱ) Histidine by Spectral Analysis & ⅱ Effect of Amount of External Added Co ( His ) n , Phosphate

缺锌和补锌对烫伤大鼠血清和组织锌含量，含锌酶、激素、蛋白质的影响

Effects of Zinc Deficiency and Supplements on Serum and Tissue Zinc Contents , Zinc-dependent Enzyme Activity , Hormone Levels , and Protein Synthesis in Scalded Rats

饲料锌水平对肉用仔鸡肝脏中含锌酶活性的影响

Effect of dietary zinc concentration on activities of zinc-containing enzymes in the liver of Broilers

不同处理间，旗叶以施锌量约为11.25～22.5kgHM~（-2）的酶活性较高，倒3叶则随施锌量增加酶活性增加。

Among the different treatments , the CA activity in flag leaf was highest at the Zn levels of 11.25-22.5 kg hm - , and the CA activity in the 3rd leaf from top , however , increased with the increasing zinc fertilization .