金属蛋白

金属蛋白研究中几个值得注意的动向

New Trends in Metalloprotein Studies

桥联多核结构广泛存在于生物体中金属蛋白和金属酶的活性部位，它们对生物体的生理和催化作用有着至关重要的影响。

Bridged polynuclear structure exists widely in the active sites of the metalloprotein and metalloenzyme in organisms that makes a great impact on their physiology and catalysis .

一种改进的同步辐射X射线荧光原位分析人肝细胞胞质溶胶内金属蛋白分布的方法

An Improved Method for Analysis of Distribution of Metalloproteins in Human Liver Cytosol by Synchrotron Radiation X-ray Fluorescence

本文观察了白细胞介素1（IL1β）和硫代腺苷蛋氨酸（SAM）对培养的肥大软骨细胞蛋白多糖（PG）分解代谢及基质金属蛋白水解酶（MMP）活性的影响。

Effect of interleukin-1 ( IL-1 β) on degradation of proteoglycan and metalloproteinase ( MMP ) activity in rabbit hypertrophic chondrocyte cultures was examined .

目的：研究涎腺肿瘤组织中基质金属蛋白2（MMP-2）表达及与微血管密度的关系。

Aim : To study the expression of matrix metalloproteinase 2 ( MMP-2 ) and its correlation with microvascular density ( MVD ) in salivary carcinoma .

基质金属蛋白水解酶10和CD（44V6）表达与甲状腺癌浸润转移关系探讨

The discuss MMP_ ( 10 ) and CD_ ( 44V6 ) deliver oneself of and the thyroid carcinoma to soakage as metastasis of the connection

根据研究结果推测，休内许多个同性质和功能的蛋白水解酶，如丝氨酸蛋白水解酶、半胱氨酸蛋白水解酶、天冬氨酸蛋白水解酶和金属蛋白水解酶等参与ADAMs的降解加工。

This paper confirmed that process and degradation of ADAMs in vivo were involved in many proteases with different properties and functions , such as the serine proteases , cysteine proteases , aspartic acid proteases , metalloproteases , etc.

炎症性肠病肠上皮细胞基质金属蛋白激酶对NAP-2的影响

Effect of matrix metalloproteinase on the neutrophil chemokine neutrophil activating peptide-2 of intestinal epithelial cells in inflammatory bowel disease

目的探讨基质金属蛋白水解酶10（MMP10）和CD44V6在甲状腺癌中的表达与甲状腺癌术后是否复发的关系。

Objective To discuss MMP_ ( 10 ) and CD_ ( 44V6 ) in the thyroid carcinoma hit of give voice to and the thyroid carcinoma warlock if recur of connection .

金属蛋白涂层支架用于小型猪冠状动脉质粒介导下转基因研究

Plasmid-mediated Intracoronary Local Gene Transfer Using Protein coated Metallic Stent in Mini swine

二氧化硅对人肺泡巨噬细胞基质金属蛋白-9表达的影响

Effect of SiO_2on the expression of MMP-9 in human alveolar macrophages in vitro

没有发现间质金属蛋白持续保持活性。

There was no consistent pattern of MMP activity .

糜烂型与网状型口腔扁平苔藓基质金属蛋白基因表达

Matrix metalloproteinase gene expression in oral lichen planus : Erosive vs. reticular forms

金属蛋白盐的制备及其抗氧化性

The preparation and antioxidant property of metal proteinate

这些成功的研究成果，丰富了我们对金属蛋白结构-性质-反应-功能之间精妙关系的深入认识。

All these successful studies provide us important information for understanding the delicate structure-property-reactivity-function relationship of metalloproteins .

金属蛋白由于有金属离子或金属辅基的帮助，具有功能高效性与多样性等特点，特别适合蛋白质工程改造。

Metalloproteins are suitable for modification and functional design due to the efficiency and diversity of their metal cofactors .

金属蛋白广泛的参与基础生命活动，在新陈代谢的化学反应中起到举足轻重的作用。

Metalloproteins are involved in a wide range of basic biological processes that represent important chemical reactions for metabolism .

金属蛋白在电极表面的形貌，取向和电学特性等的研究尤其具有吸引力。而研究蛋白质的力电效应更富有挑战性。

Study on its topography , orientation and electrical property on the surface of electrode is very necessary and attractive .

金属蛋白和金属酶中仅含少量的金属离子，但它们起至关重要的作用。

Though metal ions exist in trace amount in metalloproteins and metalloenzymes , their roles in structure or catalysis are crucial .

目前研究表明机械负载、炎性因子影响腱细胞中基质金属蛋白的表达和活性，共同作用于腱细胞时具有协同或抑制效应。

Now researches indicated mechanical loading and cytokines can regulate MMPs expression and activity , and there is a synergetic or inhibitory effect between them .

许多金属蛋白是重要的药物作用标的，也因此使得在分子嵌合模拟当中能够更适当地考虑金属离子是必要的。

Many metalloproteins are important drug targets , and hence there is a necessity to consider these metal ions more properly in molecular docking studies .

目的：观察大鼠海马内去整合蛋白和金属蛋白水解酶10和17基因表达的改变。

AIM : To investigate the change of gene expression of a disintegrin and metalloprotease ( ADAM ) 10 and ADAM 17 in hippocampus of rats .

金属蛋白大约能占到已知蛋白总数的百分之四十左右，它们参与一些基础的生化反应。

Metalloproteins that constitute almost 40 % of the proteins of the entire genome are an important class of proteins responsible of many fundamental biological processes .

本研究工作对于新型分子体铁磁材料的设计和合成，以及探索了解金属蛋白中金属离子的生物功能等方面具有一定的理论和实验指导意义。

The study will benefit the designation and the syntheses of the novel molecular magnets , and it will also benefit the understanding of the biology function of metal ions in metallic protein .

金属蛋白结构和功能关系的研究，是生物无机化学的一个重要研究课题。随着研究的深入，各种现代实验技术逐渐被应用于这一领域中。

The relation between structure and function of metal albumen in biologic-inorganic chemistry is an important research Now many advanced experimental techniques have been used gradually in this kind of field Mossbauer spectrum is an attractive technique and has been used widely .

结论烫伤组织损伤与脂质过氧化反应有一定的关系，而金属硫蛋白有一定保护作用

Conclusion MT may be attenuating lipid peroxidation of burned tissue .

金属硫蛋白对γ射线和丝裂霉素C致遗传损伤的拮抗作用

Antagonistic Effects of Metallothionein on Genetic Damage Caused by γ - Rays and Mitomycin C

用同步辐射X荧光分析法研究兔肝金属硫蛋白中的微量元素

Study on trace elements distribution in rabbit metallothioneins by synchrotron radiation X-ray fluorescence analysis

金属硫蛋白对仔猪抗氧化功能及SOD基因表达的影响

Effects of metallothionein on anti-oxidative function and SOD gene expression in piglets

检测金属硫蛋白夹心法ELISA的建立和初步应用

Establishment and preliminary application of the double antibody sandwich ELISA for measuring metallothionein