解偶联蛋白

鸡解偶联蛋白（UCP）基因与生长和体组成性状关系的遗传学研究

The SNPs of Chicken UCP Gene are Genetically Associated with Growth & Body Composition Traits

解偶联蛋白基因是新近发现的能够增加能量消耗，与脂肪代谢和能量调控密切相关的一组基因。

UCP genes are newly discovered genes that can increase the energy expenditure and involve the metabolism of fat and the regulation of energy .

糖皮质激素对大鼠解偶联蛋白mRNA表达的影响

Glucocorticoid regulates the expression of uncoupling protein mRNA in rats

解偶联蛋白-1基因3826A→G变异与2-型糖尿病的相关研究

Relationship between the 3826 A → G Variation of Uncoupling Protein-1 Gene and Type-2 Diabetes Mellitus

RT-PCR法测定脂肪组织解偶联蛋白mRNA表达水平的探讨

Quantification of uncoupling protein mRNA expression level in adipose tissue

子痫前期患者胎盘组织中解偶联蛋白2基因mRNA表达与胰岛素抵抗的关系

Relationship between expression of uncoupling proteins 2 gene mRNA in placenta and insulin resistance in preeclampsia patients

解偶联蛋白-2mRNA在LPS致热小鼠肝脏中的表达

The Expression of Uncoupling Protein-2 mRNA in Livers of Feverish Mice Caused by Lipopolysaccharide

Leptin、解偶联蛋白与能量代谢失衡

Leptin , uncoupling protein and hypermetabolism

UCP2：解偶联蛋白家族的新成员

UCP_2 : New member of uncoupling protein family

在棕色脂肪组织，p38对解偶联蛋白-1基因转录起促进作用。

The stimulatory role of p38 in transcription of the uncoupling protein 1 ( UCP1 ) gene in brown adipose tissue is relatively clear .

目的研究高脂喂养致胰岛素抵抗（IR）动物模型中胰岛素敏感性的变化及解偶联蛋白（UCPs）基因表达的改变。

Objective To explore the change of insulin sensitivity and uncoupling protein gene ( UCP ) mRNA expression in high-fat rat model of insulin resistance .

解偶联蛋白3是一种线粒体内膜上的转运蛋白，可以使氧化过程与ADP磷酸化过程解偶联。

Uncoupling protein 3 ( UCP3 ) was mitochondrial membrane transporters involved in themogenesis , which uncoupled the oxidation and phosphorylation of ADP on respiration chain .

目的：探讨解偶联蛋白-2（UCP2）在心肌缺血预适应（IPC）心肌保护中的作用。

Objective : To discuss the role of uncoupling protein 2 ( UCP2 ) in myocardium with ischemic preconditioning ( IPC ) .

与动物冷适应密切相关的解偶联蛋白（UncouplingProtein，UCP）与动物对的能量的分配与利用，以及与人类肥胖症和非胰岛素依赖性糖尿病具有密切的关系。

The uncoupling protein ( UCP ) played an important role in the adaptive thermogenesis of animals . And it also tightly associated with energy allocating and utilizing and human 's adiposity and NIDDM .

目的：研究急性运动中和运动后，骨骼肌线粒体活性氧（ROS）生成与解偶联蛋白3（UCP3）表达的相互关系，探讨骨骼肌胞浆中解偶联蛋白库的作用。

Aims The present study is to explore the implications of the skeletal muscles mitochondrial ROS generation and UCP3 expression during and after acute exercise .

目的：研究急性运动诱导线粒体活性氧（ROS）生成的过程中，线粒体内解偶联蛋白（UCPs）介导的温和解偶联（milduncoupling）和抗氧化酶这两种抗氧化体系可能的分工与协同关系及其生物学意义。

Objective The present research was to explore a possible coordination between the mitochondrial UCPs-mediated uncoupling and the antioxidant enzymes during the exercise-induced ROS generation .

瘦素（Leptin，LEP）和解偶联蛋白2/解偶联蛋白3（UncouplingProteins2and3，UCP2/UCP3）是调控食物摄入和能量消耗过程中的关键因子。

Leptin ( LEP ) and the uncoupling proteins 2 / 3 ( UCP2 / UCP3 ) are key molecules involved in the regulation of food intake and energy expenditure .

目的：解偶联蛋白2（UncouplingProtein2，UCP2）是线粒体内膜解偶联蛋白质家族成员。

Objectives : Uncoupling protein 2 ( UCP2 ) is a member of the anion carrier family localized in the inner mitochondrial membrane .

目的探讨高脂饮食诱导肥胖抵抗大鼠褐色脂肪组织（BAT）、白色脂肪组织（WAT）和骨骼肌解偶联蛋白2（UCP2）基因的表达。

Objective To explore the expression of uncoupling protein-2 mRNA in brown adipose tissue , white adipose tissue and skeletal muscle of diet-induced obesity-resistant ( DIO-R ) rats .

目的：探讨决明子、黄芪对大鼠棕色脂肪线粒体内膜解偶联蛋白（UCP）活性与含量的影响。

Objective : To evaluate the effects of Cassia seed and Astragalus on the content and activity of uncoupling protein ( UCP ) in mitochondria intima of brown fat in rats .

在QTL定位的基础上选取猪解偶联蛋白3（UCP3）作为控制脂肪沉积性状和肉质性状的候选基因。

Based on quantitative traits loci ( QTL ) mapping , porcine uncoupling protein 3 ( UCP3 ) gene was chosen as a candidate gene for pig fat deposition and meat quality traits .

近来研究表明：解偶联蛋白2（UCP2）广泛存在于组织细胞的线粒体内膜，具有抑制活性氧产生的功能。

Recently , it has been reported that Uncoupling Protein 2 ( UCP_2 ) is widespread in mitochondrial inner membrane of tissue including cadiocyte , and can decrease the production of ROS .

褐色脂肪组织（BAT）是小型哺乳动物冷适应性产热的主要器官，其产热调控的核心因素是解偶联蛋白（UCP）。

Brown adipose tissue ( BAT ) is the major sites of cold-adaptive thermogenesis in small mammals , and uncoupling protein ( UCP ) in inner membrane of BAT mitochondria is the key molecule regulating and limiting thermogenesis .

目的观察长期高脂喂养对糖尿病（DM）大鼠骨骼肌解偶联蛋白3（UCP3）基因表达的影响以及非诺贝特治疗后其表达的变化。

Aim To explore the effect of long-term high fat diet on the expression of uncoupling ( UCP3 ) gene in skeletal muscle of diabetic mellitus ( DM ) rats , and the effect of the fenofibrate therapy .

已知影响生物体内能量平衡的因素很多，由解偶联蛋白（UncouplingProteins，UCPs）调控能量诱发脂肪组织和肌肉组织的生热作用是影响机体能量平衡的重要因素之一。

It is well known that the energy balance in organic body can be caused by many factors . Uncoupling proteins ( UCPs ), regulating diet-induced adipose tissues and muscular thermogenesis , are one of the important factors affecting the body energy balance .

目的：探讨肠缺血预适应（iIPC）对心肌的保护作用以及心肌线粒体解偶联蛋白-2（UCP2）在iIPC心肌保护中的作用。

Objective : To discuss the protective effect of intestinal ischemic preconditioning ( iIPC ) on the myocardium and the role of uncoupling protein 2 ( UCP2 ) in myocardium with iIPC .

目的：观察罗格列酮对高脂喂养胰岛素抵抗（IR）大鼠动物模型的胰岛素增敏作用及对解偶联蛋白（UCPs）基因表达的影响。

Aim : To explore the effect of rosiglitazone , a ligand of peroxisome proliferator activated receptors γ ( PPAR γ) , on improving insulin sensitivity and uncoupling proteins ( UCPs ) gene mRNA expression in high fat rat model of insulin resistance .

目的探讨体外受精周期颗粒细胞解偶联蛋白2（UCP2）的表达与细胞内活性氧水平关系以及对胚胎发育的影响。

Objective To examine the expression of uncoupling protein-2 ( UCP2 ) in the granular cell of women undergoing in vitro fertilization ( IVF ) and explore its role in embryo development .

近来发现，解偶联蛋白2（UCP2）及线粒体与游离脂肪酸引起的胰岛β细胞功能障碍有关，但是其具体机制尚不明确。本实验对此作初步研究。

Recently , uncoupling protein 2 ( UCP2 ) and mitochondrion and FFAs were observed to be related with the defects of pancreatic p cell , but the mechanism is not clear .

目的探讨解偶联蛋白2（UCP-2）基因8号外显子3′-末端（3-′UTR）45bp插入/缺失（I/D）多态性与糖尿病视网膜病变（Diabeticretinopathy，DR）的关系。

Objective To investigate the association between a 45-bp insertion / deletion ( Ins / Del ) polymorphism in the 3 ′ - untranslating region ( 3 ′ - UTR ) of its exon 8 in uncoupling protein 2 ( UCP-2 ) gene and diabetic retinopathy ( DR ) .