葡激酶

α具有溶原性转换葡激酶能力，β则无。

Phage a has the ability of lysogenic conversion for production of SAK , but α has not .

重症急性胰腺炎大鼠心肌核因子-κB激活及重组葡激酶和益活清胰汤的干预作用

Myocardial NF - κ B Activity in SAP Rats and Intervention Effect of Recombinant Staphylokinase and Promote Blood Circulation Qing Yi Decoction

葡激酶突变体（K35R）PLGA微球的制备和表征（英文）

Preparation and characterization of PLGA microspheres containing a staphylokinase variant ( K35R )

重组葡激酶（r-Sak）在家兔体内的药代动力学研究

Pharmacokinetic studies of recombinant staphylokinase ( r-sak ) in rabbits

目的：用ICR小鼠研究重组葡激酶（r-SAK）的致畸作用。

Purpose : To research the teratogenic effect of recombinant staphylokinase ( r-SAK ) on ICR mice .

方法：利用水蛭素对血栓及血栓前体特异性亲合的作用特点，构建葡激酶与水蛭素C端12肽的融合基因。

Methods : Based upon the specific affinity of hirudin towards thrombin and its precursors , we constructed a fusion gene encoding the protein with a fusion point between the 12 amino acid peptide from the hirudin C terminus and the thrombolytic agent staphylokinase .

目的研究重组葡激酶（r-SAK）（抗急性心肌梗死药）单次静脉给药后在健康人体内的药代动力学。

Objective To investigate the pharmacokinetics of recombinant staphylokinase ( r-SAK ) by intravenous administration in healthy Chinese volunteers .

目的探讨重组葡激酶（r-Sak）的溶栓活性及对纤维蛋白溶解系统的影响。

Objective To investigate the effect of thrombolysis and influence to fibrinolytic system with recombinant staphylokinase ( r-Sak ) .

目的观察重组葡激酶（recombinantstaphylokinase，r-Sak）治疗实验性视网膜中央动脉阻塞（centralretinalarteryocclusion，CRAO）的效果及其对全身的影响。

Objective To inspect the effects of recombinant staphylokinase ( r Sak ) and the changes of fibrinolytic activity in the systemic circulation in the treatment of experimental central retinal artery occlusion ( CRAO ) .

采用溶氧反馈的分批培养流加补料的方法高密度培养重组大肠杆菌BL21（DE3）生产重组葡激酶-水蛭素融合蛋白。

Recombinant fusion protein staphylokinase-hirudin has been produced by adopting the dissolved oxygen feed-back fed-batch with the high cell density cultivation strategy in E. coli BL21 ( DE3 ) .

目的观察同等剂量国产重组葡激酶（r-SAK）、重组链激酶（r-SK）和尿激酶（UK）对兔股动脉血栓的溶栓疗效。

Objective To compare the thrombolytic efficacy of native recombinant staphylokinase ( r-SAK ), recombinant streptokinase ( r-SK ) and urokinase ( UK ) in equivalent doses for femoral artery thrombosis in rabbits .

目的：观察重组葡激酶（r-SaK）对中国实验小型猪冠状动脉血栓、心肌缺血、心肌梗塞的影响。

AIM : To study the effects of recombinant staphylokinase ( r-Sak ) on coronary thrombosis , cardiac ischemia , and myocardial infarction in Chinese experimental miniature swine .

目的旨在观察重组葡激酶（rSaK）对兔肺栓塞的溶栓作用。

Thrombolysis effect of recombinant staphylokinase ( rSaK ) developed in China was evaluated in rabbits with experimental pulmonary embolus model .

葡萄球菌激酶（Staphylokinase），简称葡激酶（Sak），是金黄色葡萄球菌分泌的一种胞外蛋白。多项实验表明，葡激酶是一种极具潜力的溶栓药物。

Staphlokinase ( Sak ) is a small extracellular protein secreted by numerous strains of staphylococcus aureus , many experiences indicated that Sak was a more protein and more fibrin-specific fibrinolytic agent .

目的研究微球内葡激酶突变体（K35R，DGR）的存在状态和影响其稳定性的主要因素。

OBJECTIVE To investigate the status of a staphylokinase variant ( K35R , DGR ) loaded microspheres and the main factors that influence the stability of encapsulated DGR .

葡激酶突变体K35R（DGR）是双功能葡激酶突变体，是正在开发的治疗血栓性疾病的新药.强联蛋白（Annexins）与血栓性疾病

Staphylokinase variant K35R ( DGR ) is a bifunctional protein that possesses fibrinolytic and antiplatelet aggregation activities , and is a promising drug for thrombotic disorders . Annexins and Thrombotic Disorders

目的比较动脉内注射不同剂量重组葡激酶（r-Sak）溶栓治疗犬急性脑梗死的疗效和并发症，以探讨其相对合理的治疗剂量。

Objective To compare the effect and complications of intraarterial thrombolysis with different doses of recombinant-staphylokinase ( r-Sak ) in canine model with acute cerebral infarction , and then to find out the most properly appropriate effective dose .

重组葡激酶对犬股动脉血栓的再通作用

Thrombolytic effect of recombinant staphylokinase on canine thrombus of femoral artery

国产重组葡激酶耐受性和安全性的临床试验

The clinical study of tolerance and safety of domestic recombinant staphylokinase

重组葡激酶在急性心肌梗死中的溶栓疗效

Intravenous thrombolysis with recombinant staphylokinase in patients with acute myocardial infarction

重组葡激酶的高效表达及分离纯化

High yield production and purification of recombinant staphylokinase in B.subtilis

重组葡激酶溶栓治疗的动物实验及临床研究

Efficacy of recombinant staphylokinase in animal experiment and clinical study

犬急性脑栓塞动物模型及重组葡激酶动脉内溶栓实验研究

Intraarterial Thrombolysis for Acute Cerebral Ischemic Stroke with Recombinant-staphylokinase in Animal Experimental

RGD-葡激酶的凝胶过滤层析法复性及其纯化

The Renaturation and Purification of RGD-Staphylokinase by Gel Filtration

重组葡激酶对兔实验性肺栓塞的溶栓作用

Thrombolysis by staphylokinase in rabbits with experimental pulmonary embolus

重组葡激酶治疗实验性幼猪急性脑栓塞的量效研究

Angiographic Efficacy of Recombinant Staphylokinase in Thrombolytic Therapy of Swine Acute Thromboembolic Stroke

重组葡激酶基因在大肠杆菌内的高水平表达及生物学活性研究

High-level expression of recombinant staphylokinase in Escherichia coli

表达重组葡激酶-水蛭素融合蛋白的大肠杆菌工程菌的高密度培养

High Cell Density Cultivation of Recombinant Escherichia coli for Production of Fusion Protein Staphylokinase-Hirudin

葡激酶体外定向进化的初步研究

Preliminary Study on Directed Evolution of Staphylokinase

葡激酶突变体基因的克隆与表达

Cloning and Expression of Staphylokinase Mutant Gene