脑益嗪

在脑益嗪组，SD大鼠预先注射脑益嗪，1小时后如运动病组进行旋转刺激；

In the cinnarizine group , the rotation stimulation was performed 1 hour after cinnarizine injection .

这些变化可视为脑益嗪抗运动病作用的重要机理。

These change are believed to be the important mechanism of how cinnarizine prevents motion sickness .

对照组口服脑益嗪片、维生素C片、静滴复方丹参注射液。

The control group was treated with oral cinnarizine , vitamine C and compund salvia miltiorrhiza intravenously .

脑益嗪对肝纤维化肝细胞线粒体ATP酶及Ca~（2＋）的影响

The Effect of Aplactan on Hepatic Cellular Mitochondrion ATPase and Ca ￣( 2 + ) Uptake in Rats with Hepatic Fibrosis

在脑益嗪组c－fos基因表达水平和Fos蛋白含量均低于运动病组。结论：脑益嗪抗运动病的中枢机理之一可能与c－fos基因快速表达有关。

Conclusion : The central mechanism of cinnarizine in preventing motion sickness is considered to be closely related to the quick expression of c fos gene in the brain tissues .

脑益嗪抗运动病时大鼠血浆PG和小脑Na~+K~+ATPase图像分析定量研究

Image and Quantity Analysis of Prostaglandin in Rats ' Blood Plasma and Na + K + ATPase in Their Cerebellum During the Prevention of Motion Sickness by Cinnarizine

脑益嗪对实验性血栓形成的影响

Effects of Cinnarizine on Experimental Thrombus Formation in Rats

研究了脑益嗪对受前庭刺激家兔的脑血流图功率谱和眼震颤的影响。

Effects of cinnarizine on the REG power spectrum and nystagmus of rabbits during rotatory stimulation were studied .

方法：160例头痛患者随机分为治疗组（头痛汤）和对照组（维生素B1+脑益嗪）。

Methods : 160 patients with headache were randomly allocated in treatment group ( 80 ) and control group ( 80 ) .

目的：探讨脑益嗪抗运动病作用的神经中枢机理与脑细胞c－fos基因表达的关系。

Aim : To explore the relationship between the CNS mechanism of anti motion sickness effect of cinnarizine and the c fos gene expression in the brain cells .

以旋转后产生异嗜高岭土行为的大鼠作为运动病模型，观察脑益嗪的抗运动病作用。

The rats that were subjected to rotational stimulation engaged in pica were used as the experimental models , The actions of cinnarizine in preventing motion sickness were studied .

给予大鼠及家兔旋转刺激，观察脑益嗪对旋转刺激后大鼠脑电功率谱和家兔脑血流图的影响。

Rats and rabbits were stimulated with rotation , influences of cinnarizine were then observed on EEG power spectra of rats and cerebral blood flow of rabbits after this rotatory stimulation .

实验结果提示：当前庭受过度刺激时脑益嗪可能通过扩张病理收缩状态的脑血管来对抗运动病的发生，同时也不排除其降低前庭器官敏感性的作用。

These results suggested that the protective effect of cinnarizine on motion sickness should result from a dilatation of the brain blood vessels under pathological contraction caused by vestibular stimulation and do not do away with the reduction of the sensitivity of vestibular organs .

脑血流图功率谱的计算机分析表明，有效的前庭刺激可以引起脑血管的紧张，而脑益嗪能够改善前庭刺激下的脑血流状况，并且降低旋转后眼震颤的频率和慢相速度。

Effective vestibular stimulation might cause the tension of brain blood vessels . Cinnarizine could improve the brain blood flow during the vestibular stimulation and also reduce the frequency and velocity of slow phase of post rotatory nystagmus .