肠系膜动脉

第二部分分题一通过应用辣椒素急性激活TRPV1后，观察其对小鼠肠系膜动脉舒张功能的影响。

Part two , section 1 : The vasodilation response of mice mesenteric arteries to acute administration with capsaicin was detected .

大鼠主动脉和肠系膜动脉多巴胺受体DA1亚型和年龄变化的关系

Age-dependent changes of dopamine DA_1 receptors in aortas and mesenteric arteries of rats

ERK1/2通路参与大鼠肠系膜动脉平滑肌细胞ETB受体上调表达

ERK1 / 2 pathway involved in the expression of ET_B receptors of the culturing smooth muscle cells of rat mesenteric artery

结果静脉滴注VS后，肠系膜动脉各级分支迅速收缩，肠实质显影变淡。

Results All branches of mesenteric arteries contracted and the contrast developed light in the intestinal wall after VS infusion .

Urocortin对自发性高血压大鼠肠系膜动脉血管重构的作用和大鼠心肌细胞浆膜KATP通道的作用

Effects of Urocortin on Mesenteric Arterial Remodeling and Cardiac Sarcolemmal ATP-sensitive K ~ + Channels in Rats

肾血管性高血压时脑与肠系膜动脉壁CGRP能神经纤维分布的变化

Changes of the CGRP-containing nerve fibers in the cerebral arteries and the mesenteric arteries of renal vascular hypertension

方法两肾一夹法制备RH大鼠模型，观察肠系膜动脉床和尾动脉对收缩和舒张刺激的反应性。

METHODS The contraction and relaxation of resistance vessels to stimuli were investigated in tail artery and mesenteric arteriole bed .

结论：26周龄SHR左心室与肠系膜动脉有明显的重塑现象；

Conclusion : Remolding of left ventricle and resistance vessel in 26 weeks SHR is obvious ;

离体肠系膜动脉研究发现刺激D3受体可舒张动脉血管。

Vaso-relaxation was found in ex-vivo isolated mesenteric artery when D_3 receptor was stimulated .

治疗前后检测鼠尾收缩压、淋巴细胞胞浆游离钙[Ca2+]i、血浆AngⅡ和肠系膜动脉超微结构。

Rat tail systolic press , lymphocyte cytosolic calcium ( I ), ultrastructure of mesenteric artery , plasma Ang ⅱ were measured before and after treatment .

肠系膜动脉重塑的主要原因可能系血管壁的细胞外基质（ECM）堆积，而不是平滑肌细胞增殖。

The main reason of remodeling in resistance vessels is probably that extracellular matrix ( ECM ) of vessel wall increases and not that VSMCs of vessel media hyperplasia .

目的：观察复方地黄三种不同提取物对链脲佐菌素（STZ）诱导的糖尿病（DM）大鼠肠系膜动脉舒张功能的影响。

AIM : To investigate the effects of three extracts of Fufang Dihuang decoction on the relaxation of mesentery artery in streptozotocin ( STZ ) - induced diabetic rats .

方法8例急性肠系膜动脉栓塞（MAE）确诊5例，误诊3例。

Methods In 8 cases of acute mesenteric arterial embolism ( MAE ), 5 cases were definitely diagnosed , 3 cases were made error diagnosis .

结果表明，SHR和RHR的肠系膜动脉Ca~（2+）内流显著高于主动脉；

The results indicated that Ca2 + uptake of mesenteric artery was greater than that of aorta from both SHR and RHR .

肠系膜动脉阻塞（MAE）与肠系膜静脉血栓形成（MVT）是少见的外科急腹症。

Mesenteric artery embolism ( MAE ) and mesenteric venous thrombosis ( MVT ) were rare acute abdominal disorders in the surgical fields .

结果4wk尾部悬吊大鼠股动脉和肠系膜动脉环对KCl和PE的收缩反应性较同步对照组显著降低；

Result The contractile responsiveness to KCl or PE of femoral and mesenteric arterial rings isolated from SUS significantly decreased as compared with CON .

我们以前的工作已表明，内毒素可引起降钙素基因相关肽（CGRP）从大鼠肠系膜动脉床释放，此作用部分是通过一氧化氮介导的。

Our previous work has shown that endotoxin triggers the release of calcitonin generelated peptide ( CGRP ) from the mesenteric arterial bed , which is partially mediated by nitric oxide .

缝隙连接阻断剂heptanol对内皮素收缩大鼠肠系膜动脉的抑制作用

Effect of gap junction blocker heptanol on the ET - 1-induced vasoconstriction in rat mesenteric artery

结论：EMD为非内皮依赖性血管平滑肌松弛剂，对冠脉的松弛作用约为肠系膜动脉的2倍。

CONCLUSION : EMD is a non endothelium dependent preparation for vascular smooth muscles relaxation , the relaxing action of EMD on mesenteric artery is two times that of coronary artery .

方法采用随机分组方法，用夹闭肠系膜动脉根部45min、再灌注6h制备大鼠MODS模型。

Methods A rat model of MODS was reproduced by occluding the superior mesenteric artery for 45 minutes followed by reperfusion for 6 hours .

目的观察N-已酰半胱氨酸（N-Acetylcysteine，NAC）对离体大鼠肠系膜动脉内皮依赖性血管舒张作用以及通过增加一氧化氮（NitricOXide，NO）的活性达到扩张血管的作用。

Objective ln order to observe N-Acetylcysteine ( NAC ) enhances vasorelaxation of isolated mesenteric artery of endothelium-dependent in rats and NAC can enhances vasorelaxation from increase activity of nitric oxide ( NO ) .

结论：1.血管紧张素Ⅱ的促人肠系膜动脉平滑肌增殖作用的机制可能部分是通过血管紧张素ⅡNADPH氧化酶活性氧通路来实现。

Human mesenteric artery smooth muscle proliferation induced by angiotensin ⅱ may party get access to the angiotensin ⅱ - NADPH oxidase - active oxygen species pathway . 2 .

血管紧张素ⅡNADPH氧化酶活性氧通路对高血压病人的肠系膜动脉平滑肌细胞促增殖作用较非高血压病人更强。

Angiotensin ⅱ - NADPH oxidase - active oxygen species pathway , by comparison , plays a more significant role in the hypertensive patients mesenteric artery smooth muscle cellar proliferation .

方法：对我院肠系膜动脉阻塞和肠系膜静脉阻塞的病例进行回顾性研究，计算APACHEII和SAPSII评分及其预测死亡率。

Methods : Retrospective study on the cases of mesenteric arterial occlusion and mesenteric venous occlusion in our hospital was done . Scores of APACHE II and SAPS II as well as the predicted death rate were calculated .

目的：探讨前列腺素E1（PGE1）对人肠系膜动脉平滑肌细胞钙激活钾通道（KCa）活动的影响。

Objective : To study the effect of PGE 1 on calcium-activated potassium channels ( K Ca ) from human mesentery artery smooth muscle cell ( SMC ) .

SHR血浆、心肌、肠系膜动脉的AngⅡ无明显增高，AngⅡ水平升高不是SHR高血压及其心血管重塑的原因；

Ang ⅱ level of plasma , left ventricle myocardium , mesenteric arteries in SHR is not higher than that in WKY , hypertention and remodeling of cardiovascular in SHR is not due to increasing Ang ⅱ level .

方法以大鼠肠系膜动脉为标本，考察阿托品对去甲肾上腺素（NE）预收缩血管的舒张作用以及血管内皮细胞、血管平滑肌在该效应中的作用。

Methods Isometric tension was recorded in isolated rat super mesenteric arteries precontracted by noradrenaline ( NE ) to study the vasodilation effect of atropine , and to investigate the role of endothelial cell and vascular smooth muscle cell on vasodilation .

方法通过大鼠离体肠系膜动脉环（superiormesentericarterialrings，MARs）试验，观察GJ阻断剂Heptanol预处理对PE引起的去内皮和完整内皮MARs收缩及其量效曲线的影响。

METHODS By using isolated rings of rat superior mesenteric arteries ( MARs ), without and with endothelium , the effects of GJ blocker heptanol on the PE-induced vasoconstriction and concentra tion-effect curves were recorded as changes in isometric force .

我们在离体肠系膜动脉床研究了内毒素引起糖尿病大鼠CGRP释放的改变以及一氧化氮所起的作用。

In the present study , the changes of endotoxin-induced CGRP release from the isolated mesenteric arterial bed and the CGRP mRNA levels in dorsal root ganglia ( DRG ) of diabetic rats were studied in relation to the effect of nitric oxide .

我们以往的工作证实成年自发高血压大鼠（SHR与SHRsp）肠系膜动脉由乙酰胆碱引起的内皮依赖性舒张（EDR）减弱。

It was verified in our previous study that endothelium-dependent relaxation ( EDR ) in the mesenteric artery strip of adult spontaneously hypertensive rats ( SHR and SHRsp ) was decreased upon addition of acetylcholine ( ACh ) .