美西律

结论：美西律可以用来治疗LQT3。

CONCLUSION : Mexiletine may be an effective drug in the treatment of LQT_3 .

美西律对大鼠背根神经节细胞钠电流的抑制作用

Inhibition of mexiletine on sodium current in dorsal root ganglion neurons of rats

固定pH滴定法测定弱酸性药物盐酸美西律

Determination of metronidazole hydrochloride by pH - fixed titration

盐酸美西律及其片剂的毛细管GC测定

Determination of Mexiletine Hydrochloride and Its Tablets by Capillary GC

PVC膜美西律电极测定小檗碱

Determination of berberine using PVC membrane mexiletine selective electrode

美西律（20μg／kg）能逆转ATX-Ⅱ的这种电生理作用。

This electrophysiological effect of ATX - ⅱ could be reversed by mexiletine ( 20 μ g / kg ) .

PVC美西律选择性电极的研制

PVC membrane mexiletine selective electrodes

胺碘酮美西律普罗帕酮对QT离散度影响的临床观察

Clinical Study of Amiodarone , Mexiletine and Propafenone on QT Dispersion

Nafion修饰玻碳电极对微量美西律的测定

Determination of Microamount mexiletine with Nafion-modified glassy carbon electrode

方法将（±）-美西律与大鼠肝微粒体孵育后，采用柱前衍生化毛细管气相色谱-氢火焰离子化检测法测定了酶促反应的时间曲线及动力学参数Vm和Km值。

METHODS The time course and the parameters of enzymatic kinetics of mexiletine enantiomers , V_m and K_m , were determined by a capillary gas chromatographic system with flame ionization detection .

观察了美西律治疗16例（男6例，女10例；年龄54±12a）糖尿病性神经疼痛的临床疗效。口服美西律0.1-0.2g，tid，共4wk。

This paper reports 16 diabetic patients ( M 6 , F 10 ; age 54 + 12 a ) suffered from neuralgia were treated with mexiletine 0.1-0.2g , tid , po , for 4 wk .

目的：制备LQT3模型（一种QT延长综合症），研究美西律对LQT3模型的作用。

AIM : To make a LQT_3 model ( one form of the long QT syndromes ) and to investigate the effect of mexiletine on LQT_3 . METHODS : Sea anemone toxin ( ATX ⅱ) was used to produce the LQT_3 model .

用该法测定盐酸美西律弱酸性药物获得满意效果。

The method has used to determine metronidazole hydrochloride with very satisfactory results .

美西律治疗糖尿病性神经疼痛16例

Diabetic neuralgia treated with mexiletine in 16 patients

毛细管电泳分离盐酸美西律对映体机理的研究

Mechanism Study on Chiral Recognition of Cyclodextrin for Separation of Mexiletine Enantiomers by Capillary Electrophoresis

美西律组的有效率为66.2%；2组有效率经x~2检验P>0.05，无统计学意义；

The effective rates of 2 groups were insignificant statistically ( P > 0.05 ) .

以四苯硼酸-美西律离子缔合物为活性材料，制成了美西律选择性涂丝电极，并对影响该电极性能的诸因素进行了较详细的研究。

The coated wire of mexiletine selective electrode made with ion-association complex of mexiletine-tetraphenylborate was studied .

针刺内关穴配合美西律治疗频发室性早搏30例疗效观察

Treatment of Frequent Ventricular Premature Beats by Needling Neiguan Point Associated with Mexiletine : A Clinical Observation of 30 Cases

首先，我们通过自由能计算比较了普罗帕酮和美西律之间，以及各自对映体之间的结合能差异，与实验结果得到的趋势基本一致。

The calculated binding energy difference trends between propafenone and mexiletine or between their enantiomers were correlated well with previous experimental results .

本文研究了用美西律电极测定小檗碱（黄连素）的方法，并对电极的多种性能进行了测试。

The method for determining berberine using PVC membrance Mexiletine selective electrode is presented and several characteristics of the electrode are also tested .

应用环糊精-毛细管区带电泳体系对手性药物盐酸美西律和盐酸异博定的对映体分离进行了研究。

The enantiomeric separation of chiral drugs mexiletine and verapamil was investigated using cyclodextrins added buffers at acidic conditions in capillary zone electrophoresis .