磷脂酰丝氨酸
- phosphatidyl serine, phosphatidylserine
-
磷脂酰丝氨酸(PS)转位等方法检测细胞凋亡。
Apoptosis was detected by translocation of phosphatidylserine ( PS ) by flow cytometry .
-
蛋白激酶c的特异性活化剂&磷脂酰丝氨酸(PS)和甘油二油酸酯(DO)不促进这一磷酸化。
The specific activators of protein kinase C , phosphatidylserine ( PS ) and diolein ( DO ) showed no stimulation on phosphorylation .
-
细胞凋亡早期,磷脂酰丝氨酸(PS)从细胞膜脂双层的内层迁移至外层。
Phosphatidylserine exposures on the outer leaflet of the plasma membrane lipid bilayer at the beginning of apoptosis .
-
脑中磷脂酰丝氨酸(PS)是在基团交换酶作用下生成的。
Biosynthesis of brain phosphatidylserine ( PS ) depends on base exchange reaction catalyzed by base exchange enzymes .
-
用细胞形态学、流式细胞术检测磷脂酰丝氨酸(PS)转位及细胞凋亡;
Apoptosis was detected by morphological observation and translocation of phosphatidylserine ( PS ) was examined by flow cytometry assay ;
-
线粒体凋亡途径包括细胞膜磷脂酰丝氨酸翻转、胞内活性氧水平升高、线粒体功能障碍、释放细胞色素c、激活半胱氨酸蛋白酶等环节。
This pathway including several processes such as cell membrane phosphatidylserine translocation , intracellular reactive oxygen species level increase , mitochondria dysfunction , cytochrome c release , caspases activation and so on .
-
结论NO介导的小鼠胸腺细胞的凋亡过程,依次为磷脂酰丝氨酸外翻、线粒体去极化、CL氧化及细胞皱缩。
CONCLUSION : The process of thymocyte apoptosis mediated by NO in mice is successively PS ectropion , mitochondrial depolarization , CL oxidation and cell crenation .
-
Annexin-V结合分析检测靶细胞磷脂酰丝氨酸外化;
The phosphatidylserine exposure was identified with the help of Annexin-V binding assay ;
-
结果:FITC标记的AnnexinB1与凋亡细胞膜表面磷脂酰丝氨酸(phosphatidylserine,PS)结合,使凋亡细胞呈阳性着色,能有效检测细胞凋亡。
Results : The FITC labelled Annexin B1 efficiently detected apoptosis with positive fluorescent signal when it bound to phosphatidylserine on apoptotic cell membrane .
-
结论DEX诱导小鼠胸腺细胞发生典型细胞凋亡和线粒体去极化增强,在该进程中,线粒体去极化增强发生在细胞膜磷脂酰丝氨酸外翻之前。
Conclusion DEX can induce typical apoptosis and mitochondrial depolarization of thymocytes , and the mitochondrial depolarization occurs before exposure of membrane phosphatidyl serine .
-
这种蛋白激酶具有Ca2+依赖、CaM和磷脂酰丝氨酸不依赖等特性,与已在多种植物中报道的含有类似钙调素结构域的蛋白激酶CDPK相似。
The protein kinase was Ca 2 + _dependent and CaM and phosphatidylserine_independent , like the calmodulin_like domain protein kinase ( CDPK ) in many plants .
-
另一方面DHA发生脂质过氧化因而减少了膜上DHA的水平,导致膜上磷脂酰丝氨酸减少,抑制了细胞内PI3K/Akt信号通路转导,从而抑制肿瘤细胞生长。
Lipid peroxidation may decrease DHA levels in cell membrane and lead to reduced phosphatidylserine in intracellular membrane , which blocks the PI3K / Akt signaling pathway and leads to cell growth inhibition .
-
CAI对MCF-7细胞的凋亡诱导作用通过两种方法测定:应用流式细胞仪分析细胞的亚二倍体凋亡峰以及使用AnnexinV-FITC/PI凋亡检测试剂盒定量分析磷脂酰丝氨酸外翻。
Apoptosis induction by CAI in MCF-7 cells was assessed by ( I ) flow cytometry analysis of sub-G_0-G_1 DNA content and ( ii ) quantification of phosphatidylserine exposure using annexin V-FITC kit .
-
经0.4g·L-1磷脂酰丝氨酸,0.04g·L-1甘油二油酸酯激动剂作用酶粗提物后,用液体闪烁计数仪计数[γ32P]ATP参入外源底物的量以测定PKC活性。
PKC activity was measured by incorporation of [ γ 32 P ] ATP into exogenous substrate after stimulated by phosphatidylserine and diolein .
-
体外试验已证实了KIM-1是一种独特的磷脂酰丝氨酸受体,可赋予肾小管上皮细胞吞噬功能,有利于凋亡坏死细胞的清除,减轻小管梗阻。
In vitro studies have demonstrated that KIM-1 is a unique phosphatidylserine receptor , which endues renal tubular epithelial cells with phagocytotic function and , thus , helps scavenge apoptotic and necrotic cells and relieve tubular obstruction .
-
凋亡细胞暴露出磷脂酰丝氨酸并迅速被巨噬细胞吞噬。
Apoptotic cells expose phosphatidylserine and are swiftly engulfed by macrophages .
-
精子质膜磷脂酰丝氨酸外翻与线粒体膜电位的关系
Relationship Between Sperm Plasma Membrane Translocation of Phosphatidylserine and Mitochondrial Transmembrane Potential
-
磷脂酰丝氨酸的中枢神经作用
The action on central nervous system of phosphatidylserine
-
磷脂酰丝氨酸外翻和磷脂氧化在凋亡细胞被吞噬细胞清除过程中的协作效应
Cooperation effect of externalized phosphatidylserine and oxidized phospholipids on clearance of apoptotic cells by macrophages
-
线粒体膜电势完整性和磷脂酰丝氨酸的浆膜转位作为早期凋亡标记:两种不同精子亚群的比较
Mitochondrial membrane potential integrity and plasma membrane translocation of phosphatidylserine as early apoptotic markers : A comparison of two different sperm subpopulations
-
同时,靶细胞磷脂酰丝氨酸外化率显著高于阴性对照组(0.24vs0.03)。
Meanwhile , the phosphatidylserine exposure rate of target cells was markedly increased in teh Na Sal group ( 0.24 ) vs the control ( 0.03 ) .
-
鱼类中的ω-3脂肪酸对大脑很有好处,海洋鱼类如鲭鱼、鲱鱼、鳗鱼和金枪鱼都含有大量的磷脂酰丝氨酸。
The omega-3 fatty acids found in fish ( and nuts ) are great for the brain . Sea swimmers like mackerel , herring , eel and tuna are also chock full of phosphatidylserine .