硫氧还蛋白过氧化物酶
- 名thioredoxin peroxidase
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提高细胞内氧化状态而诱导蛋白质硫氧还蛋白过氧化物酶1的表达,并可能通过该蛋白质调控NF-κB和AP-1来影响细胞生长。
EBV might increase the oxidation in cells so as to induce the expression of protein " thioredoxin peroxidase 1 ", and then regulate the expression of NF - κ B and AP-1 via thioredoxin peroxidase 1 to affect cell growth .
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与能量代谢有关的蛋白质:硫氧还蛋白过氧化物酶(TPX1);
Protein associated with energy metabolism : thioredoxin peroxidase 1 ( TPX1 );
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与细胞增殖、分化、抗凋亡及肿瘤相关。研究表明,硫氧还蛋白过氧化物酶Ⅱ在红细胞及K-562红白血病细胞系中作为巯基特异性的抗氧还剂。
Prx isotypes ( I-VI ) are associated with the cellular proliferation , differentiation , and antiapoptotic effect , and their expression is relevant to cancer . Prx II was identified as a thiol-specific antioxidant in the K-562 erythroleukemia cell line and erythrocytes , respectively .
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多头带绦虫硫氧还蛋白过氧化物酶基因的克隆、表达及抗原性研究
Cloning , Expression and Antigenicity Analysis of Thioredoxin Peroxidase Gene of Taenia Multiceps
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真空对氧化镁碳热还原影响分析(英文)多头带绦虫硫氧还蛋白过氧化物酶基因的克隆、表达及抗原性研究
Study on the thermodynamic and experimental carbothermic reduction magnesia Cloning , Expression and Antigenicity Analysis of Thioredoxin Peroxidase Gene of Taenia Multiceps
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硫氧还蛋白过氧化物酶家族在多种细胞功能中发挥重要作用,如抗氧化损伤保护蛋白和脂质,细胞增殖、分化,调节凋亡过程中细胞内信号传导等。
Prxs play a key role in several cellular functions including protein and lipid protection against oxidative injury , cell proliferation , differentiation and intracellular signaling pathways regulating apoptosis .
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硫氧还蛋白过氧化物酶Ⅰ、Ⅱ和Ⅲ在人乳腺癌组织中过表达,并与肿瘤的发展和分级相关。
Three types of Prx ( I , II , and III ) have been shown to be over-expressed in the case of human breast cancer , and it has been suggested that their over-expressions are related to cancer development or progression .
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硫氧还蛋白过氧化物酶Ⅱ存在于红细胞及人脐内皮细胞的胞浆中,同时表达于人体表皮肤的良恶性血管瘤。
Prx II has been reported to be present in the cytoplasm of RBCs and human umbilical endothelial cells . In a previous study , Prx II is expressed in endothelial cells of benign and malignant vascular tumors in human skin in vivo .