益生菌

胶囊型益生菌保健食品HACCP系统的应用研究

Application of HACCP System to the Production of Probiotic Capsulae

结论：早期应用益生菌辅助治疗SAP，可改善其病程及预后。

Conchlsion : The Early application of probiotic can improve the course and prognosis of SAP .

乳酸菌（LacticAcidBacteria，LAB）是被世界公认的益生菌。

Lactic acid bacteria ( LAB ) is the world-recognized probiotics .

益生菌DGGEMarker的制备及验证

Preparation and verification of the DGGE Marker of probiotics

结论1.益生菌DNA滴鼻干预通过降低动物模型IgE水平，缓解Ⅰ型变态反应性。

Conclusions : 1 . probiotics DNA therapeutic intervention by reducing animal model IgE levels , remission of type I allergy . 2 .

本试验研究了日粮添加益生菌制剂对断奶仔猪的生产性能、免疫指标、肠道形态结构、pH值和挥发性脂肪酸的影响。

This experiment was conducted to study the effects of probiotic preparation on growth performance , immune indexes , morphology , pH Valus and Volatile Fatty Acids of weaner piglets .

溃疡性结肠炎患者J形回肠袋肛管吻合重建术后经4周的益生菌干预，其临床症状及内镜下表现的结果

Outcome of four weeks ' intervention with probiotics on symptoms and endoscopic appearance after surgical reconstruction with a J-configurated ileal-pouch-anal-anastomosis in ulcerative colitis

此次研究通过对具有血管紧张素转化酶（ACE）抑制功能的益生菌进行体外筛选及评价，得到高活性的候选菌株。

By screening and appraising the probiotics which could inhibit angiotensin-convertion enzyme in vitro , the high-activity candidate strains were obtained .

在益生菌保健食品生产领域建立危害分析与关键控制点（HACCP）系统，并验证其可行性和有效性。

To investigate and evaluate the feasibility and validity of HACCP system for its application in production of probiotic capsules .

乳酸链球菌（简称乳链菌）被证实是安全和有效的益生菌（probiotics），已长期应用于临床实践。

Lactococcus lactis has been confirmed to be safe and effective , and used clinically for many years .

三个月前，她收到台南市的益生菌原料（LAB）&声称有减肥效果。

Three months ago , she received some raw material from Tainan municipality of lactic acid bacteria or LAB , which is claimed to have fat losing effects .

口服益生菌预防早产儿严重坏死性小肠结肠炎疗效和安全性的Meta分析

The effect of oral probiotics on the prevention of necrotizing enterocolitis in preterm infants : a meta-analysis of its efficacy and safety

炎症性肠病动物模型的建立及外源性IL-10和益生菌诱导粘膜免疫耐受治疗炎症性肠病的效应探讨

Investigation on the Construction of Animal Model of Inflammatory Bowel Disease and the Therapeutic Efficacy of Mucosal Tolerance Induced by IL-10 and Probiotic

目的观察益生菌对溃疡性结肠炎（UC）大鼠结肠黏膜IL-1βmRNA和TNFαmRNA表达的影响。

Objective To investigate the effects of probiotics on the expression of IL-1 β mRNA and TNF - α mRNA in the colonic mucosa of rats with ulcerative colitis .

统计分析表明，仔猪口服益生菌S1对其盲肠和结肠菌群的多样性指数无显著影响。

Statistical analysis showed that treatment with S1 had no marked effect on diversity index of predominant bacteria from hindguts in piglets .

外周血液T、B淋巴细胞数量和血清IgG、IgM、IgA含量较未饲喂益生菌的对照雏鸡不同程度增加。

The number of T and B lymphocytes and the content of IgG , IgM , IgA in peripheral blood increase in different extent as compared with those of control chicks .

目的探讨健康儿童口服法国合生元益生菌冲剂后的唾液中sIgA（分泌型IgA）含量的变化，从而判定其对提高消化道黏膜免疫的作用。

The change of secreted IgA ( sIgA ) concentration in saliva from children who took orally Biostime Children 's Probiotic Sachet was monitored .

DGGE法研究甘露寡糖、益生菌与抗生素对仔猪肠道微生态的影响

A study on the effect of mannan oligosaccharides , probiotics and antibiotics on intestinal micro-ecology by the DGGE method

妇科腹腔镜手术后早进饮食的探讨结论适度提前进食、肠内营养及口服肠道益生菌等治疗措施有助于降低SAP后期感染率，改善预后。

Conclusions Treatment with bifidobacterium and lactobacillus mixture , enteral feeding and early eating are helpful for not only preventing secondary infection after SAP but also improving the prognosis of SAP .

因此，应用益生菌治疗或辅助治疗UC，已经成为UC基础和临床研究的重要课题之一。

Therefore , the application of probiotics treatment or adjuvant treatment to UC which has become one of the important topics in the basic and clinical researches .

有研究表明UC患者肠道菌群结构发生改变，通过给予益生菌调节肠道微生态环境，可使患者病情得到明显改善。

Some researches have shown that intestinal microflora structure of UC patients is changed , it can be significantly improved by giving probiotics to regulate intestinal micro-environment .

结果：急性毒性试验表明，小鼠灌胃给予富硒益生菌，其LD50为18.49g/kg。

RESULTS : The oral acute toxicity study revealed that the LD50 of selenium-enriched probiotics was 18.49 g / kg in mice .

益生菌治疗IBD取得了一定疗效，但临床治疗评价尚需大宗病例的随机对照长期观察研究。

Probiotics treatment IBD obtained the certain curative effect , but the clinical treatment evaluation still need to large cases of randomized controlled long-term observation research .

目的观察补充益生菌对葡聚糖硫酸钠（DSS）诱导的小鼠结肠炎的影响，探讨益生菌对结肠炎的治疗作用和可能机制。

Objective To investigate the effect of bifidobacterium ( Bif ) supplementation on acute inflammatory response in murine dextran sulfate sodium ( DSS ) - induced colitis , and its possible mechanism .

目的评价不同剂量益生菌对大鼠实验性结肠炎的疗效，研究治疗后全身及肠道局部调节性T细胞（Tr）的变化情况，探讨益生菌作用机制。

Objective To evaluate the effects of probiotics on experimental colitis of rats and to explore systemic and local changes of T regulatory cells ( Tr ) after the treatment .

益生菌LGG的研究

Review on studies of probiotics

将活性嗜酸乳杆菌、双歧杆菌冻干菌粉按工艺要求添加到原料中制得益生菌AB咀嚼奶片，并对该奶片的配方设计、工艺流程、工艺要点及产品易出现的质量问题做了研究。

Milk slice of probiotic AB was developed by adding freeze-dried powder of Lactobacillus acidophilus and Bifidobacterium , and the formula design , processing technology , key processing and product quality problems easily occurring were studied .

牛源肠道益生菌芽孢杆菌BN-9菌株的分离鉴定

Separating and Identification of Probiotics Bacillus Strains BN-9 from Bovine Intestine

结果SASP和益生菌均可显著改善UC大鼠结肠黏膜的病理变化，且明显降低黏膜中IL-1βmRNA和TNFαmRNA的表达。

Results The stages and histological changes were improved obviously and the expression of IL-1 β mRNA and TNF - α mRNA in the colonic mucosa of rats with ulcerative colitis decreased by using probiotics and SASP .

由此可初步判定，在人体推荐摄入剂量每天50mg范围内使用富硒益生菌是安全可靠的。

Thus , selenium-enriched probiotics was safe at the daily-recommended dose ( 50 mg / person / day ) and has the potential for development into functional foods .