氢化可的松

HPLC法测定复方氢化可的松栓剂中维生素E的含量

Determination of Vitamin E in Compound Hydrocortisone Suppository by HPLC

反相HPLC法测定血浆中的氢化可的松和甲基强的松龙

Determination of Hydrocortisone and Methylprednisolone in Plasma by Reversed & P has e HPLC

高效液相色谱中流动相pH值对氢化可的松琥珀酸钠保留行为的影响

Effect of pH Value of Mobile Phase in HPLC on the Retention Behavior of Hydrocortisone Sodium Succinate

治疗前后2组血浆氢化可的松均在正常范围内，2组间比较P＜0.05。

Although all mean plasm hydrocortisone level were within the normal range , they were significantly different between 2 groups ( P < 0.05 ) .

结论联合使用丝裂霉素C和氢化可的松局部作用于大鼠鼓膜大穿孔边缘，可以成功制作慢性持续性鼓膜穿孔的动物模型。

Conclusions Topically applied mitomycin C and hydrocortisone on the perforation rims may create an animal model of chronic persistent tympanic membrane perforation successfully .

结论：氢化可的松具有抑制IL-1α诱导的角膜基质细胞胶原降解的作用。

Conclusion Hydrocortisone can inhibit keratocyte-collagen degradation induced by IL-1 α .

方法采用弗氏完全佐剂建立SD大鼠佐剂性关节炎模型，分别给予奇任醇、氢化可的松、阿司匹林加环磷酰胺治疗；

Methods AA rat model was made by means of Freund 's complete adjuvant .

HPLC测定结肠黏膜中氢化可的松的浓度及其局部作用机理初探

Determination of the hydrocortisone in colonic mucosa and exploring its mechanisms of the local effect of hydrocortisone by HPLC

目的：探讨氢化可的松在白细胞介素1α（IL-1α）诱导的角膜基质细胞降解中的作用。

Objective To investigate the effects of hydrocortisone on degradation of keratocyte induced by interleukin-1 α( IL-1 α) .

氢化可的松琥珀酸钠（HSS）作为模型药物。

Hydrocortisone sodium succinate ( HSS ) was used as a model drug .

结论氢化可的松可减少TXA2、TNF-α、IL-6等炎症因子的产生等从而对SAP具有重要的治疗保护作用。

Conclusion Hydrocortisone may have therapeutic effects on SAP by decreasing the production of TXA_2 TNF - α IL-6 .

方法采用MTT比色法，观察氢化可的松对体外培养的肾小管上皮细胞增殖的影响。

Methods After being stimulated by hydrocortisone at different concentration , the proliferation of renal tubular epithelial cells were determined by MTT methods .

在相同浓度下，不同的GC对IACh的抑制效力B＞地塞米松（Dex）＞氢化可的松（F）。

At the same concentration of GC , the rank of the inhibitory potency was B > dexamethasone ( Dex ) > hydrocortisone ( F ) .

结论：IVIG联合氢化可的松佐治婴儿重症喘憋性肺炎有较好疗效。

Conclusions : IVIG and Hydrocortisone in treating infants with severe asthmatic suffocating pneumonia is effective .

氢化可的松、辛伐他汀、维生素C对高脂饮食大鼠动脉NF-KB、ICAM-1含量影响实验研究

The Study to the Influence of Hydrocortisone and Simvastatin and Vitamine C on the Content of NF-KB and ICAM-1 in the Aorta of Hypercholesterolemic Rats

【方法】经60Co照射和氢化可的松联合免疫抑制建立了17只大鼠肝癌模型。

Liver cancer models in 17 rats were established by 60 Co irradiation and combined immuno-suppression with hydrocortisone .

目的：分析小牛胸腺肽（TP）改善氢化可的松（HC）抑制骨髓造血功能的作用。

Objective : To analyse the improving effect of thymic peptides ( TP ) on hemopoietic function of bone marrow inhibited by hydrocortisone ( HC ) .

结论：甲硝唑注射液与氢化可的松注射液配伍后在25℃下8h内稳定。

CONCLUSION : The compatibility of metronidazole injection with hydrocorti ˉ sone injection is stable at25 ℃ within8hours after combination .

目的探讨氢化可的松体外对酪氨酸酶活性影响，以及对小鼠B16黑素瘤细胞株细胞增殖、黑素合成以及细胞内酪氨酸酶活性的作用。

AIM To study the effect of Hydrocortisone injection on tyrosinase activity and the melanogenesis of B 16 murine melanoma cell .

目的研究小剂量氢化可的松（HC）对内毒素诱导的脓毒症大鼠脑功能障碍的影响及核因子κB（NFκB）信号转导途径在发病机制中的作用。

Objective To investigate the effects of low-dose hydrocortisone on brain dysfunction in LPS-induced sepsis rats and the role of nuclear factor kappa B ( NF - κ B ) signal transcription pathway in the pathogenesis .

该细胞在添加胰岛素、氢化可的松以及羊催乳素的无血清培养液中诱导培养时，用RT-PCR方法检测到了β-酪蛋白基因的转录。

The transcription of the beta - casein gene was detected by RT - PCR , when the purified cells were induced with insulin , hydrocortisone and prolactin in the culture medium without serum .

从第8天起，NS+HD组和RSJ+HD组小鼠肌注氢化可的松0.02g/（kg·d），连续7d。

The rats in NS + HD and RSJ + HD groups were injected hydrocortisone by 0.02 g / ( kg · d ) from the eighth day to fourteenth day .

目的探讨不同剂量氢化可的松（hydrocortisone，HC）对内毒素休克早期大鼠内环境的影响。

Objective To investigate the effects of different dosages of hydrocortisone ( HC ) on the disorder of homeostasis in rats at early stage of endotoxic shock .

这些结果为肢端肥大症患者的治疗提供了重要的借鉴，并要求为ACTH缺乏的患者寻求更为合理的氢化可的松用药方法。

These results have important implications for the treatment of patients with acromegaly and also raise issues as to the optimum hydrocortisone treatment regimens for ACTH-deficient patients .

目的：观察静脉注射丙种球蛋白（IVIG）联合氢化可的松治疗婴儿重症喘憋性肺炎的疗效。

Objective : To evaluate the clinical effect of Intravenous Immune globulin ( IVIG ) and Hydrocortisone on infant with severe asthmatic suffocating pneumonia .

目的：探讨氢化可的松对脂肪栓塞综合征（FES）血液流变学、氧分压（PaO2）以及预后的影响。

Objective : To study the effect of hydrocortisone on hemorheology , PaO 2 and prognosis of fat embolism syndrome ( FES ) .

目的：分析胸腺肽（TP）对长期使用氢化可的松（HC）并致敏的小鼠免疫器官与免疫功能的影响。

Objective : To analyse the effect of thymic peptides ( TP ) on immune organs and immune function of mice sensitized and under long term hydrocortisone ( HC ) administration .

目前国内外对新月弯孢霉的研究主要集中在其对化合物RSA的羟基化生产氢化可的松和由其引起的玉米、水稻等植物病害上。

The study of Curvularia lunata mainly focused on its production of Hydrocortisone by hydroxylating compound RSA and its causing corn , rice and other plant disease at home and abroad recently .

方法用氢化可的松探针测定健康儿童个体内CYP3A酶活性。

METHODS The hydrocortisone probe was used to determine the CYP3A activity .

方法：应用HPLC梯度洗脱法测定50例原发性高血压患者和34例健康志愿者尿中氢化可的松和可的松的比值，以比较其肾11β-羟化类固醇脱氢酶（11β-HSD）活性的差异。

- hydroxysteroid dehydrogenase ( 11 ? - HSD ) activity in 50 patients with essential hypertension and 34 healthy volunteers . METHODS : The ratio of cortisol and cortisone in urine were measured by HPLC gradient delivery method .