模式识别受体

Toll样受体（TLR）蛋白家族属于动物模式识别受体家族。

Toll like receptor ( TLR ) belong to animal pattern recognition receptor family .

上述结果表明Vg是一种多价的模式识别受体。

These results indicated that Vg was a multivalent pattern recognition receptor .

Toll样受体是一类参与天然免疫的病原模式识别受体，其与营养物质间的关系及机制尚不清楚。

Toll-like receptors is a kind of Pattern recognition receptor ( PPR ), and the relationship between TLRs and nutritions is not clear .

肽聚糖识别蛋白（Peptidoglycanrecognitionprotein，PGRP）是一类模式识别受体，在昆虫的先天性免疫反应中起着重要的作用。

Peptidoglycan recognition protein is an important pattern recognition receptor and play an important role in the insect innate immune response .

Toll样受体，作为重要的模式识别受体，能通过识别不同的病原微生物，活化特异的信号通路，起始细胞因子的表达。

Toll-like receptors , serve as pattern recognition receptors ( PRRs ), activate specific signaling pathways that initiate the production of cytokines through recognizing different microbial components .

结论：NOD蛋白可能为Af的胞浆内模式识别受体（pattern。recognitionreceptors，PRRs），在抗Af肺部感染的免疫反应中发挥一定作用。

Conclusion : NOD proteins may be the cytoplasmic pattern recognition receptors of Aspergillus fumigatus , and play a role in immune defense on pulmonary Aspergillus fumigatus infection .

C型凝集素受体（CLR）是模式识别受体家族中有别于TLR的新家族，在机体免疫应答中发挥着重要作用。

C-type lectin receptors ( CLR ), which play an important role in the immune response , are a new family of pattern recognition receptors .

第三，进一步观察了细菌LPS、细菌脂蛋白和细菌DNA对肺泡巨噬细胞表面上述模式识别受体表达的影响及其对细胞激活的协同作用；

To further determine the synergistic effects of LPS , BLP and bacterial DNA on the expression of pattern recognition receptors ( PRR ) on the cell surface of mouse alveolar macrophages and cellular activation ;

To11样受体是新发现的先天性免疫的病原模式识别受体，在机体抵抗外来病原生物入侵上起关键的作用。

Toll-like receptors play a crucial role in the host defense against invading microorganisms by recognizing pathogen-associated molecular patterns .

Toll样受体是目前研究最清楚的一类模式识别受体，它能识别多种病源微生物相关的分子模式，并在机体抗感染免疫中发挥重要作用。

Toll-like receptors ( TLRs ), the best-characterized receptors among the pattern recognition receptors ( PRRs ), recognize a diverse range of pathogen associated molecular patterns and play a critical role in antimicrobial host defense .

从低等生物开始，C型凝集素受体（CLRs）作为一类重要的模式识别受体（PRRs）就一直发挥着识别病原体、抵抗感染的作用。

As an important class of pattern recognition receptors ( PRRs ), C-type lectin receptors ( CLRs ) have played crucial roles in pathogens recognition and infection .

Toll样受体（Toll-Likereceptors，TLRs）是天然免疫中重要的模式识别受体超家族，在机体抗病原体感染中发挥重要的作用，同时也是连接天然免疫与获得性免疫的桥梁。

Toll-like receptors ( TLRs ), a superfamily of pattern-recognition receptors ( PRRs ) play a pivotal role in host innate immunity against pathogen infection and bridge the innate and adaptive immune .

模式识别受体（PRR）的深入研究极大地发展了固有免疫反应机制的理论。

Pattern recognition receptor ( PRR ) has been intensively studied and shed light in innate immune reaction mechanisms .

细胞模式识别受体（PRR）能特异性识别病毒分子或其复制产物而产生IFN与炎性细胞因子。

The IFN and inflammatory response against viral infections is mediated by cellular pattern-recognition receptors ( PRR ) that recognize specific molecular structures on viral particle or products of viral replication .

近年来，本课题组一直在研究甘露聚糖结合凝集素（mannan-bindinglectin，MBL）的免疫调节作用，但它是一个存在于血清中的可溶性模式识别受体。

In recent years , Our research group has been studying immunoregulation of MBL ( mannan-binding lectin ) which is a soluble pattern recognition receptors existed in the serum .

RNA解旋酶维甲酸诱导基因-Ⅰ（RIG-Ⅰ）是新发现的细胞内重要的模式识别受体，能识别胞内的dsRNA进而诱导IFN的产生，激活特异性免疫而发挥抗病毒作用。

RNA helicases Retinoic acid induced gene-I ( RIG - ⅰ) is a newly discovered pattern recognition receptor ( PRR ), acting as a cytoplasmic dsRNA receptor and inducer of IFN production , to activate antiviral immune responses .

目的观察脓毒症主要相关细胞因子肿瘤坏死因子α（TNFα）和干扰素γ（IFNγ）对巨噬细胞表面主要模式识别受体（PRRs）表达的影响。

Objective To investigate the effects of tumor necrosis factor alpha ( TNF alpha ) and interferon gamma ( IFN gamma ) on the expression of pattern recognition receptors ( PRRs ) on the surface of mouse alveolar macrophages .

固有免疫是在进化中形成的免疫机制，在对抗微生物的入侵方面，固有免疫的策略是通过模式识别受体（PRR）识别微生物的病原相关分子模式（PAMP）。

In protection against microbes , an organism recognizes the pathogen associated molecular pattern ( PAMP ) on microbes by pattern recognition receptor ( PRR ) .

通过体外实验，从效应细胞表面病原菌相关模式识别受体（CD14、TLR4、TLR2、TLR9）水平进一步观察了细菌LPS、BLP和CpG-ODN对天然免疫细胞的协同刺激效应及其可能机制。

The synergistic effects of LPS , BLP and bacterial DNA were further examined in vitro at the level of PRRs on the cell surface of effector cells using cultured primary alveolar macrophages .

Toll样受体（Tolllikereceptors，TLRs）是新近发现的模式识别受体，能识别病原相关分子模式，启动炎性应答通路而调节或控制先天与获得性免疫。

The family of Toll-like receptors ( TLRs ) is a new pattern-recognition receptors ( PRRs ), which recognize specific pathogen-associated molecular patterns ( PAMPs ) . Recognition of PAMPs by PRRs results in the activation of inflammatory process , which subsequently control the innate and adaptive immune response .

脂多糖模式识别受体的研究进展

Recent advance in research of pattern recognition receptors for LPS

无脊椎动物先天免疫模式识别受体研究进展

Progress in Pattern Recognition Receptors of Innate Immunity in Invertebrates

模式识别受体与病毒感染

Pattern recognition receptors and viral infections

模式识别受体识别病原相关分子模式，启动丝氨酸蛋白酶级联反应。

Recognition of pathogens by pattern recognition receptors can trigger activation of a serine protease cascade .

天然免疫系统通过一系列高度保守的模式识别受体识别病原体相关分子模式。

The innate immune system recognizes pathogen associated molecular patterns through a series of pattern recognition receptors .

腹腔感染脓毒症时肺内主要模式识别受体表达变化及其与肺损伤的关系

The relationship of the expression of principal pattern recognition receptor with the pulmonary injury in abdominal infection-induced sepsis

天然免疫系统通常籍模式识别受体识别病原体相关分子模式。

Pathogen recognition by the innate immune system is commonly based on the identification of pathogen-associated molecular patterns by the pattern-recognition receptors .

它们在先天免疫中作为模式识别受体发挥作用，并具有其他多种功能。

They play roles as the receptors to recognize the pathogen patterns in the immune system , and also other various functions .

研究证明，这种非己识别是因为存在某些特异性的、可溶的或与细胞膜结合的模式识别受体，可以识别或结合微生物表面保守的、而在宿主中又不存在的病原相关分子模式。

Different pattern recognition proteins recognize and bind to molecules ( pathogen associated molecular patterns , PAMPs ) present on the surface of microorganisms but absent from animals .

巨噬细胞能通过细胞表面受体来识别入侵机体的病原体，在众多的表面受体中，甘露糖受体是重要的病原体模式识别受体之一。

Receptors of Macrophage can recognize invading bacteria , in a large number of surface receptors , the mannose receptor is an important pathogen pattern recognition receptor of macrophage .