折叠中间体

折叠中间体，折叠中间态物体的中心点或中点。

Folding intermediate the center point or middle of something .

二级结构随温度的变化暗示了折叠中间体的存在。

The changes of secondary structures with temperature suggest the presence of folding intermediates .

用高效疏水色谱法对多种脲变α-淀粉酶折叠中间体的研究

Studies on the Various Refolded Intermediates of α - Amylase Denatured by Urea with High Performance Hydrophobic Interaction Chromatography

针对蛋白质聚集问题，开展抑制聚集方法研究，发现与蛋白质带有同种电荷的离子交换介质能够很好地抑制折叠中间体聚集从而促进蛋白质复性。

Herein we found that electrostatic repulsion between like-charged protein and ion exchange gel beads can greatly suppress the aggregation of folding intermediates , leading to the significant increase of native protein recovery .

β-折叠结构中间体的疏水性很强，很容易发生积聚。

The β - sheet form is highly hydrophobic and is prone to self-aggregation .