慢性排斥反应

结论OKT3治疗难治性排斥反应的效果优于ATG，尤其对再次移植患者，但对慢性排斥反应患者无效。

Conclusion OKT3 is better than ATG for reversing the refractory rejection , especially in retransplant patients , but it has no any effect on chronic rejection .

慢性排斥反应发生率分别为：3.2%和8.3%（P<0.05）；

% ( P < 0.05 ), of chronic rejection was 3.2 ? % and 8.3 ?

维生素E对移植器官慢性排斥反应的影响

Effect of vitamin E on the chronic graft rejection

急性排斥反应组与慢性排斥反应组间差异无统计学意义（P0.05）。

( P0.01 ) There was no significant difference in acute rejection groups and chronic rejection groups ( P0.05 ) .

肾移植术后抗HLA和MICA抗体在移植肾慢性排斥反应中的临床研究

Clinical Investigation of Effect of HLA and MICA Antibodies on Chronic Allograft Rejection after Renal Transplantation

结论HBO在预防或减轻同种移植肾慢性排斥反应中能起重要的作用。

Conclusions HBO could play important role in preventing or reducing chronic allograft rejection .

目的探讨高压氧（hyperbaricoxygenation，HBO）对移植肾慢性排斥反应的防治作用及其机制。

Objective To explore the efficacy of hyperbaric oxygenation ( HBO ) on preventing renal allograft chronic rejection .

结果：CsA治疗的慢性排斥反应组，移植心脏的细胞凋亡率显著增高。

Results : The apoptotic rate was increased significantly in the group of chronic rejection treated with CsA .

目的通过观察白细胞介素5（IL5）对人嗜酸性粒细胞（Eos）中转化生长因子TGFβ1基因表达的影响，以阐明其在Eos相关性慢性排斥反应中的作用。

Objective To investigate the effects of IL 5 on the expression of TGF β 1 in eosinophils in vitro .

CD40通路在同种异体急性、慢性排斥反应的发生，发展过程发挥重要作用。

CD40 pathway plays an important role in occurrence and development of acute and chronic allograft rejection .

目的应用大鼠异位心脏移植模型研究粉防己碱（TET）对慢性排斥反应（CR）的抑制作用。

Objective Using rat heterotopic cardiac allografts transplantation model , the efficacy of tetrandrine ( TET ) in treatment of chronic rejection was investigated .

结论经门静脉注射两种或两种以上供体活细胞可减轻慢性排斥反应，VEGF、ET-1的表达与血管硬化及纤维化程度呈正相关。

Conclusions Injection of two or more kinds of donor live cells may alleviate chronic rejection via decreasing of expressions of VEGF and ET-1 in the grafts .

用补体裂解片断C4d监测大鼠移植肾慢性排斥反应

C4d : an effective indicator for monitoring chronic rejection of renal allograft in rat

对于难治性和慢性排斥反应、严重肝功能损害和牙龈增生等患者切换FK506治疗，是一种较好的方法。

It might be a better measure for FK506 treating knotty and chronic rejection , severe liver function damage , gingival hyperplasia .

结果：5例移植胰腺，MRI发现2例正常，1例急性排斥反应，1例慢性排斥反应伴纤维化和1例迟发性胰腺炎。

Results : In five transplant pancreas , MRI found two normal pancreas grafts , one case of acute rejection , one case of chronic rejection with 70 % fibrosis and one case of late pancreatitis .

异种器官移植面临的免疫学障碍表现为超急性排斥（HAR），急性血管排斥反应（AVR），细胞介导的排斥反应和慢性排斥反应。

Xenotransplantation faces several immunologic barriers : hyperacute rejection ( HAR ), acute vascular rejection ( AVR ) and chronic rejection mediated by cell .

结论肾移植术后PRA不仅与急性排斥反应有关，而且与慢性排斥反应、移植物失功有关；

Conclusion The elevation of PRA after transplantation is correlated not only with acute rejection , but also related to chronic rejection and late graft loss .

3例移植肾发生急性肾小管坏死（ATN）伴急性排斥反应，6例发生慢性排斥反应，4例发生难治性排斥反应，均经治疗后逆转；

ATN accompanied with acute rejection occurred in 3 cases , chronic rejection in 6 cases and knotty rejection in 4 cases .

目的：探讨慢性排斥反应移植体动脉硬化与血小板衍化生长因子A（PDGFA）链、胰岛素样生长因子1（IGF1）表达的关系。

Objective : To investigate the relationship between the expressions of PDGF A , IGF 1 and the transplanting arteriosclerosis of chronic rejection .

方法比较86名HCV感染和86名非HCV感染病人肾移植术后1,3,5年人/肾存活率和急、慢性排斥反应的发生率，并对死亡病例的原因进行分析。

Methods The recipient / graft survival , the incidence of acute / chronic rejection and cause of death in 86 HCV-infected recipients of renal transplantation were compared with those in another 86 recipients without HCV infection .

目的探讨霉酚酸酯（MMF）联合小剂量环孢素A（CsA）和泼尼松（Pred）治疗肾移植术后慢性排斥反应的临床效果。

Objectives To investigate the clinical efficacy of mycophenolate mofetil ( MMF ) combined with low dose CsA and prednisone ( Pred ) for treatment of chronic rejection in primary cadaveric renal recipients .

目的探讨小剂量FK778对大鼠移植肾慢性排斥反应的预防作用。

Objective To study the effect of low-dose of FK778 in preventing chronic renal allo-graft rejection in rats .

术前外周静脉负载供体抗原的受体imDC，联合术后短期使用免疫抑制剂能有效抑制术后急、慢性排斥反应，显著延长同种心脏移植物的存活时间。

Preoperative infusion alloantigen-pulsed host imDC via peripheral intravenous , combined with postoperative short-term using immunosuppressive agents could effectively inhibit postoperative acute and chronic rejection , and significantly prolonged allogeneic heart graft survival time .

结论：VCAM-1的表达水平与排斥反应的程度成正相关，测定受体VCAM-1的水平可以预测移植器官的功能状况，从而为慢性排斥反应的早期诊断和预防提供依据。

Conclusion : The expression level of VCAM-1 is associated with the occurrence and the development of rejection and has positive correlation with the severity of graft rejection . The function of allografts may be predicted and it provides evidence for early diagnosis and prevention of CR by detecting VCAM-1 .

目的研究移植物慢性排斥反应血管变化的机制，评价新型诱导型一氧化氮合酶（iNOS）抑制剂（FR260330）防治大鼠腹主动脉移植术后慢性排斥反应的作用。

Objective To evaluate the effects of a novel inducible nitric oxide synthase ( iNOS ) inhibitor ( FR260330 ) in prevention of chronic rejection in a model of rat aortic allograft and to investigate the mechanism of the arterial wall lesion of chronically rejecting solid organ grafts .

胆道免疫性损伤与肝移植急、慢性排斥反应、免疫抑制方案调控有关。

Biliary immune damage was related with acute or chronic rejection .

火把花根防治同种移植肾慢性排斥反应实验研究

Preventive Effect of Tripterygium Hypoglaucum on Chronic Allograft Nephropathy in Rats

影响供肾质量因素与移植肾急性、慢性排斥反应关系分析

Relationship between the Quality of Donor Grafts and Kidney Transplantation Rejection

急性排斥反应及病毒感染与慢性排斥反应的发生有关；

Acute rejection and viral infection may lead to chronic rejection .

雌激素预防大鼠同种肾移植慢性排斥反应的实验研究

Efficacy of estrogen in preventing chronic renal allograft rejection in rats