基因沉寂
- 网络RNA silencing
基因沉寂-
小片段发夹RNA的制备及其对Hela细胞端粒酶基因沉寂作用研究
Small Hairpin RNA Synthesis and Its Silence Effect on Telomerase Gene Expression in Hela Cells
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自从发现双链21碱基小干扰RNA可以引发特异性的基因沉寂，双链RNA介导的RNA干扰已经逐渐在抑制基因表达方面得到了广泛的应用。
Since the discovery that synthetic double-stranded 21-nt small interfering RNA is enough to trigger gene-specific silencing , double-strand RNA-mediated interference ( RNAi ) has recently emerged as a powerful reverse genetic tool to silence gene expression in multiple organisms including plants , Caenorhabditis elegans , Drosophila and mammalian cells .