嘌呤核苷酸

论肌肉嘌呤核苷酸循环的作用

The Role of Purine Nucleotide Circulation in Skeletal Muscle

在骨骼肌内，嘌呤核苷酸循环有几个方面的作用显得尤其重要。

Some functions of Purine Nucleotide circulation in skeletal muscle are of great importance .

海洛因对大鼠C6细胞核酸及嘌呤核苷酸代谢的影响

Effect of Heroin on Gene Expression of Nucleic Acid and Nucleotides Metabolism in C6 Glioma Cell

人红细胞游离嘌呤核苷酸水平是估价非胰岛素依赖型糖尿病NIDDM疾病过程的重要参数。

Human erythrocyte purine nucleotides levels are important parameters for assessing the course of the disease in patients with non-insulin-dependent diabetes mellitus ( NIDDM ) .

结论：海洛因给药使脾中ADA、XOD活力升高，引起嘌呤核苷酸分解代谢增强，而且脾细胞核苷酸分解代谢增强是海洛因依赖引起的免疫力下降的重要原因。

Conclusion Administration of heroin can enhance the activities of ADA and XOD and promote the purine nucleotides catabolism in spleen .

结论嘌呤核苷酸可诱导肠上皮细胞凋亡，嘧啶核苷酸UMP可解除嘌呤核苷酸的凋亡诱导作用。

Conclusion Purine nucleotides induce apoptosis of IEC-6 , pyrimidine nucleotides UMP could abolish the apoptosis-inducing effects of purine nucleotides .

吗啡促进大鼠小肠嘌呤核苷酸分解代谢关键酶XO的活性，纳洛酮不能阻断该作用。

Morphine may increase the activity of the key enzyme of purine nucleotides catabolism in the small intestine , which is related to the increasing of gene expression .

次黄嘌呤鸟嘌呤磷酸核糖转移酶（Hprt）参与嘌呤核苷酸的补救合成。恶性疟原虫次黄嘌呤鸟嘌呤黄嘌呤磷酸核糖转移酶细胞免疫保护作用的研究

The enzyme hypoxanthine-guanine phosphoribosyltransferase ( HPRT ) plays an important role in the purine salvage pathways . Evaluation of Cell-mediated Protective Immunity to Hypoxanthine Guanine Xanthine Phosphoribosyl Transferase ( HGXPRT ) of Plasmodium Falciparum

6-氯-2-氨基嘌呤核苷酸合成、光谱性质及生化评价

Synthesis , Spectroscopic Properties and Biochemical Evaluation of 6-Chloro-2-aminopurine Nucleoside Triphosphate

吗啡在基因水平对脑嘌呤核苷酸代谢的影响

Effect of morphine on purine nucleotides metabolism in gene level

吗啡对大鼠嘌呤核苷酸分解代谢的促进作用及其可能的作用机制

Promotion of morphine on rat purine nucleotides catabolism and its possible mechanisms

不同动物棕色脂肪组织解偶联蛋白与嘌呤核苷酸结合之比较

Binding of Purine Nucleotides to Brown Adipose Tissue Uncoupling Protein from Different Kinds of Animals

大强度运动对大鼠嘌呤核苷酸代谢的影响及运动模型研究

Effects of High Intensity Exercise on Purine Nucleotide Metabolism of Rats And Study of Motor Model

~（60）Co&γ线照射对人和动物体内环嘌呤核苷酸水平的影响

Effect of ~ ( 60 ) co - γ - irradiation on the cyclic purine nucleotide levels in animals and man

从现在的研究情况来看，在阿片类依赖戒断时，涉及了神经系统、神经内分泌系统、细胞内信号转导调控系统、嘌呤核苷酸代谢系统等一系列复杂的微观调控系统的改变。

During the opioid dependence , a series of regulation systems have been changed in recent research , such as neuronal system .

以不同动物棕色脂肪组织的亚线粒体片段为标本，对解偶联蛋白与各种嘌呤核苷酸结合的亲和程度进行测定。

Using brown adipose tissue submitochondrial particles from different kinds of animals , binding of uncoupling protein to different purine nucleotides was estimated .

次黄嘌呤是体内嘌呤核苷酸分解代谢的中间产物，是疾病诊断、食品分析等方面的重要指标之一。

Hypoxanthine is a metabolite in the degradation of adenine nucleotide . The measurement of hypoxanthine is important in clinical diagnosis and food industry .

氨的主要来源：短时间高强度运动为骨骼肌的嘌呤核苷酸循环，长时间力竭性运动主要与骨骼肌大量摄取支链氨基酸有关。

Ammonia originates mainly from PNC in skeleton muscles in high intensity exercises , and from BCAA ( branched-chain amino acids ) in exhaustive endurance exercise .

观察大强度运动对大鼠嘌呤核苷酸代谢的影响，同时分析所建运动模型的可行性。

The effects of high intensity exercise on purine nucleotide metabolism of rats were studied in this paper . Simultaneously , the feasibility of the motor model was discussed .

结论：吗啡影响神经细胞嘌呤核苷酸代谢，使细胞内腺苷酸及腺苷水平增高，这可能是吗啡依赖和耐受形成的机理之一。

Conclusion Morphine may affect purine nucleotide metabolism of nerve cells , increase the adenylate and adenosine levels , which may be one of the mechanism of morphine dependence and tolerance .

目的：通过研究吗啡对大鼠脑组织嘌呤核苷酸代谢的影响，寻找吗啡依赖相关的调控与效应基因。

Objective : To observe the changes of purine nucleotide metabolism of rat central nervous system during morphine dependence and withdrawal , and look for regulating and domino effect related to morphine dependence .

脑缺血及其再灌注后可通过花生四烯酸代谢途径、嘌呤核苷酸代谢途径及一氧化氮途径产生自由基，可能是血脑屏障通透性增加的重要机制。

Free radicals were produced in the process of arachidonic acid metabolism , adenosine purine nucleotide metabolism and nitric oxide pathway after cerebral ischemia and reperfusion , which may be an important mechanism of BBB permeability alteration .