呋喃酮

一类新型手性呋喃酮的不对称Michael加成反应

The asymmetric Michael addition reaction of a new type of chiral furanone

2,5-二甲基-3（2H）-呋喃酮的合成研究

Study on Synthesis of 2,5-dimethyl-3 ( 2h ) - furanone

4－羟基－2，5－二甲基－3（2H）呋喃酮的合成

The Synthesis Of 4-Hydroxy - 2 , 5-dimethyl - 3 - ( 2H ) - furanone

5-烷氧基-2（5H）-呋喃酮在有机合成中的应用

Application of 5-Alkoxy-2 ( 5H ) - furanone in Organic Synthesis

高产2，5-二甲基-4-羟基-3（2H）-呋喃酮酵母菌株的选育及培养环境的研究

Breeding and Culture Environment of Yeast Strains with High Production of 2 , 5-Dimethyl-4-Hydroxyl-3 ( 2H ) - Furanone

3-氯-4-二氯甲基-5-羟基-2（5氢）-呋喃酮诱导人胚胎肝细胞ras基因突变

Mutation of ras Genes Induced by 3-chloro-4 - ( dichloromethyl ) - 5-hydroxy-2 [ 5H ] - furanone in Human Fetal Hepatocytes

溴代2（5H）-呋喃酮对绿脓杆菌生物膜形成的抑制作用

The Inhibitory Effects of Brominated 2 ( 5H ) - Furanones on the Biofilms of P.aeruginosa

2（5H）-呋喃酮的过氧化氢氧化法合成与表征

Synthesis of 2 ( 5H ) - furanone by oxidation of furfural with hydrogen peroxide and its characterization

背景与目的：研究两种人类来源的肝细胞在评价饮水氯化消毒副产物3-氯-4-二氯甲基-5-羟基-2（5氯）-呋喃酮（MX）DNA损伤作用的敏感性。

BACKGROUND & AIM : To study on the susceptibility of two human-derived hepatic cell lines in evaluating DNA damage induced by 3-chloro-4-dichloromethyl-5-hydroxy-2 ( 5H ) - furanone ( MX ) .

手性3-溴-2（5H）-呋喃酮的合成及其串联的不对称Michael加成反应的研究

Studies on Synthesis of Novel Chiral 3 - Bromo - 2 ( 5H ) - Fura - None and Its Application in Tandem Asymmetric Michael Reaction

氯化消毒饮用水中强致突变物MX[3-氯-4-（二氯甲基）-5-羟基-2（5H）-呋喃酮]的形成

Formation of strong mutagen [ 3-chloro-4 - ( dichloromethyl ) - 5-hydroxy-2 ( 5h ) - furanone ] MX in chlorinated drinking water

以丁二酮为主要原料，经缩合、脱羧反应，以62.3%的总收率合成了2,5-二甲基-3（2H）-呋喃酮。

Dimethyl-3 ( 2H ) - Furanone is synthesized using biacetyl as basic material . by means of condensation and decarboxylation with the total yield amounting to 62.3 % .

本文总结了2，5&二甲基-4-羟基-3（2H）-呋喃酮的文献合成方法，并对绿色化工技术和绿色化工设计进行了综述。

In this paper , the synthetic methods of 2 , 5-dimethyl-4-hydroxy-3 ( 2H ) - furanone are summarized . The green technology of chemical process and the green chemical design are also reviewed .

研究了2（5H）-呋喃酮、5-羟基-2（5H）-呋喃酮与环戊二烯发生Diels-Alder反应，产物用FT-IR、1HNMR、MS进行了表征。

Diels-Alder reaction of 2 ( 5H ) - furanone and 5-hydroxy-2 ( 5H ) - furanone with cyclopentadiene was studied and the structure of product was characterized by FT-IR , ~ 1H NMR and MS.

MX[3氯4（二氯甲基）5羟基2（5H）呋喃酮]是饮用水氯化消毒过程中产生的具有强致突变作用的副产物。

MX [ 3 chloro 4 ( dichloromethyl ) 5 hydroxy 2 ( 5H ) furanone ] was found to be the most potent mutagen in chlorinated drinking water .

3氯4（二氯甲基）5羟基2（5H）呋喃酮（MX）及二氯乙酸（DCA）和三氯乙酸（TCA）是氯化消毒副产物（DBPs）研究的重点。

MX ( 3 Chloro 4 ( dichloromethyl ) 5 hydroxy 2 ( 5H ) furanone ) and chlorinated acetic acids such as DCA and TCA have always been the focus of Disinfection by products ( DBPs ) study .

采用重氮乙酸乙酯（EDA）与乳酸乙酯在二水杨醛铜（Ⅱ）催化下进行O&H插入反应合成了香料呋喃酮前体化合物α-甲基-缩二乙醇酸二乙酯。

Ethyl diazoacetate ( EDA ) undergoes a facile bis ( salicylaldehydato ) copper (ⅱ) carbenoid mediated O-H insertion reaction with ethyl lactate to afford the title compound . The title compound was used as a synthetic precursor for flavor : 2,5-dimethyl-4-hydroxyl-3 ( 2H ) - furanone .

对一类核苷类似物的关键中间体&（4R，5R）4（N甲基羟氨基）5[（叔丁基二苯基硅烷基）氧甲基]3,4二氢2（5H）呋喃酮的合成进行了研究。

Synthesis of ( 4 R , 5R ) - 4 - ( N - methyl-hydroxyamino ) - 5 - ( tert - butyldiphenylsiloxymethyl ) - 3,4-dihydro-2 ( 5H ) - furanone , key intermediate for a series of nucleoside analogs , was studied .

报道了光学纯5－（1－氧基）－3，4－二取代－2（5H）－呋喃酮的1HNMR和13cNMR数据，研究了不同取代基对结构以及核磁参数的影响。

The 1 ￣ H NMR and 13 ￣ C NMR of a series of compounds of optically pure 5 - ( 1-menthyloxy ) - 3,4 - disubstituted-2 ( 5H ) - furanone are reported . The effect of substituent groups on structure and NMR parameter has been studied .

该化合物可作为香料呋喃酮的合成前体。

The title compound was used as synthetic precursor for flavors .

二甲基呋喃酮诱发黑腹果蝇生殖细胞非整倍体效应的研究

Induction of aneuploidy mutation in the germ cells of drosophila

呋喃酮的制备及其绿色工艺设计

Preparation of 2 , 5-Dimethyl-4-Hydroxy-3 ( 2H ) - Furanone and Its Green Design

呋喃酮化学研究进展

< title > search Progress on Furanone Chemistry

呋喃酮纯度的研究分析

The Analysis for the Purity of Furanone

合成香料呋喃酮前体化合物α-甲基-缩二乙醇酸二乙酯的新方法

A novel synthetic process of precursor compound of flavor furaneol : ethyl 2 - ( 2-ethoxy-2-oxoethoxy ) - propionate

近年来随着咪唑以及呋喃酮等香料需求的增加，丙酮醛的需求也在逐步升高。

In recent years , the demand for methylglyoxal increased with the rise of the demand for imidazole and furanone .

根据小试情况，对呋喃酮制备工艺中反应、萃取、结晶、回收等过程单元进行了绿色化设计，并得到一条绿色概念流程。

On the basis of experimental results in the lab , the preparation processes including reaction , extraction , crystallization and recycling have been designed .

呋喃酮在中国的香精香料行业中具有不可替代的地位，因此开发低成本的呋喃酮合成工艺，显得尤为必要。

It is of great importance to develop a low-cost process for the preparation of furanone due to its significant position in Chinese flavor industry .

HPLC和ELISA法检测食品中呋喃唑酮

Determination of Furazolidone in Food by HPLC and ELISA

饲料中呋喃唑酮的HPLC法测定

Determination of Furazolidone in Feedstuff with HPLC