催化亚基

小鼠cAMP依赖的蛋白激酶催化亚基α的重组表达研究

Study on Expression of the Recombinant Mouse Catalytic Subunit α of cAMP-dependent Protein Kinase

一般认为端粒酶的蛋白催化亚基和RNA亚基组成了核心酶，它们对体外活性是必需的。

It is believed that telomerase catalytic subunit and RNA subunit constitute the core enzyme , which is essential for the telomerase activity in vitro .

DNA依赖蛋白激酶催化亚基与细胞周期蛋白T2相互结合的鉴定

Identification of interaction between DNA - dependent protein kinase catalytic subunits and cyclin T 2

牛肠激酶催化亚基cDNA的克隆、表达及表达产物的纯化和应用

Purification and Application of Bovine Enterokinase Catalytic Subunit ( EK_L ) Expressed from the Cloned cDNA Encoding EK_L

端粒酶是一种特殊的逆转录酶，它能在体内延伸染色体单链末端，在体外延伸寡聚核苷酸。一般认为端粒酶的蛋白催化亚基和RNA亚基组成了核心酶，它们对体外活性是必需的。

Telomerase is a specialized reverse transcriptase that elongates the single-stranded chromosome ends and oligonucleotides in vivo and in vitro .

端粒酶蛋白催化亚基（hTRT）mRNA在口腔鳞癌形成过程中的表达

Telomerase hTRT mRNA Expression in Oral Squamous Cell Carcinogenesis

cAMP和PKA的调节亚基结合，释放出其催化亚基而激活了PKA。

CAMP combines the regulatory subunit , releases the catalytic subunits and activates the PKA .

膀胱肿瘤中端粒酶催化亚基（hTERT）的表达

Expression of human telomerase reverse transcriptase ( hTERT ) in bladder cancer

人端粒酶催化亚基hTERT基因启动子的克隆

Cloning and characterization of human telomerase catalytic subunit ( hTERT ) gene promoter

端粒酶催化亚基hTERT在肿瘤治疗中的研究进展

Progression and study of the catalytic subunit of human telomerase ( hTERT ) in tumor therapy

PKA的催化亚基作为激酶中代表性的结构，是这十几年研究的热点。

The catalytic subunit that serves as a model for the protein kinase family is research hotspot in the recent years .

多数真核细胞的端粒酶能将单一重复序列加到端粒DNA的3′末端.端粒酶主要由模板RNA和端粒酶蛋白催化亚基组成，后者以前者为模板起逆转录酶的作用。

The core enzyme actually consists of two components : an RNA , which serves as template for the simple sequence tracts , and a catalytic subunit of telomerase that acts as a reverse transcriptase on the RNA template .

柚皮素和橙皮素对重组人肌醇磷脂3-激酶p110β催化亚基的影响

Effect of naringenin and hesperetin on recombinant human phosphoinositide 3-kinase p110 β catalytic subunit

典型的CDK催化亚基包含300个氨基酸催化核心，而当CDK独立存在和非磷酸化时是完全没有活性的。

The typical CDK catalytic subunit contains a 300 amino acid catalytic core that is completely inactive when monomeric and unphosphorylated .

三种黄酮类化合物对重组人肌醇磷脂3-激酶p110β催化亚基活性的影响

Effect of Three Flavones on Enzyme Activity of Recombinant Human Phosphoinositide 3-kinase p110 β Catalytic Subunit

端粒酶催化亚基TERT在小鼠配子发生中的表达检测及对EL-4淋巴瘤细胞增殖调节的研究

Studies on Expression of Telomerase Reverse Transcriptase ( TERT ) in Gametogenesis and TERT Regulation of Cell Proliferation in EL-4 Lymphoma Cells of Mouse

为此，我首先制备并纯化了一种本实验室正积极研究的在脊椎动物眼睛和其它组织中起重要作用的蛋白&丝/苏氨酸蛋白磷酸酶2A催化亚基p（PP-2Acβ）的GST融合蛋白。

To do so , I first generated and purified the GST fusion protein with the catalytic subunit of PP-2A , an important protein serine / threonine phosphatases in vertebrates eye and other tissues that have been actively studied in our laboratory .

在本论文中，我们将重点研究和阐述PP-1的催化亚基C的异构体γ（Gama）基因（PP-1cy）在动物胚胎的生长发育过程中的功能与作用。

In this paper , we will focus on elucidating the function of the gene of the catalytic subunit isomer y ( PP-1cy ) in the growth and development of animal embryos .

目的：研究柚皮素和橙皮素对重组人肌醇磷脂3-激酶（PI3-K）p110β催化亚基酶活性的影响。

Objective : To study the effect of naringenin and hesperetin on activity of recombinant human phosphoinositide 3-kinase ( PI3-K ) p110 β catalytic subunit .

这一新方法同样可用于在细胞裂解液中分析PKA催化亚基的含量。（4）首次提出了一种基于石墨烯／多肽复合物和羧肽酶降解作用的激酶活性分析方法。

The feasibility of this novel strategy for cellular catalytic subunit of PKA was also demonstrated in cell lysates . ( 4 ) A fluorescent principle for kinase activity assay based on grapheme / peptide complex and peptide digestion was presented .

Ⅰ型蛋白磷酸酶（PP1），通过去磷酸化蛋白调节机体代谢、细胞分化以及信号转导等。它由催化亚基和调节亚基组成，后者决定磷酸酶的底物特异性，活性以及亚细胞定位。

PP1 is composed of catalytic subunits and regulatory subunits , which modulates metabolism , cell differentiation and signal transduction by dephosphorylation . The regulatory subunits determine the substrate specificity , activity and subcellular localization of PP1 .

犬贾第虫端粒酶催化亚基基因的克隆及序列分析

Clone and sequence analysis of telomerase reverse transcriptase gene from Giardia canis

膀胱移性细胞癌尿脱落细胞端粒酶催化亚基检测及临床意义

Detection of human telomerase catalytic Subunit in urine exfoliative cells from transitional cell carcinoma of bladder

主要由一个催化亚基α亚基和一个糖基化的β亚基组成。

The enzyme is composed of a catalytic α subunit and a glycosylated β - subunit .

杨梅素、槲皮素和山萘黄素对重组人PI3Kp110β催化亚基活性的影响

Effects of myricetin , quercetin and kaempferol on activity of recombinant human phosphoinositide 3-kinase p110 β subunit

端粒酶催化亚基脱氧核酶可显著抑制人肺腺癌A549/DDP耐药细胞的生长，并且与化疗药物顺铂有协同作用，提示端粒酶有可能成为耐药肿瘤细胞新的治疗靶标。

It is suggested that telomerase might be a new target for the treatment of drug-resistance lung cancer cell .

目的：通过端粒酶催化亚基基因转入人胚肺成纤维细胞，激活人胚肺成纤维细胞端粒酶活性，探讨其在延缓细胞衰老中的作用。

Objective : To investigate the role of telomerase activation in aging by maintaining cultures of hTRT_transduced human fetal lung fibroblasts .

具催化活性的异种亚基杂合青霉素G酰化酶

Catalytically Active Cross - species Heterodimers of Penicillin G Acylase