五味子甲素

目的：建立HPLC法测定五酯胶囊中五味子甲素含量的方法。

Objective : To establish a HPLC method for the determination of deoxyschizandrin in Wuzhi Capsule .

结果：法多索溶剂能有效地提取五味子甲素，提取率为0.45%（w/w），与10%甲醇调节的超临界CO2的提取率（0.48%）接近。

Results : Phytosol solvent can extract effectively deoxyschizandrin and the yields ( 0.45 % , w / w ) obtained with phytosol A , B or D were close to that ( 0.48 % ) obtained with 10 % methanol modified supercritical carbon dioxide .

方法复制小鼠CCl4肝损伤模型，用五味子甲素和五味子醇甲防治，用生化方法测定血清ALT、AST、ALB和TP。

Method Mouse model of CCl 4-induced hepatic damage was established and deoxyschizandrin and schizandrin were used for protecting the liver against damage , then levels of serum ALT , AST , ALB and total protein were determined by biochemical method .

目的：建立肝泰胶囊中的五味子甲素的含量测定方法。

Objective : To establish a determination method for deoxyschizandrin in traditional Chinese drug Gantai capsule .

五味子甲素通过上述作用机制，进而增加肿瘤细胞内的药物浓度，达到有效杀灭肿瘤细胞的作用。

The deoxyschizandrin increased the drug concentration in tumor cells to kill tumor cells by affecting these mechanisms .

通过建立人口腔癌耐药（耐长春新碱）细胞株裸鼠移植瘤模型，评价不同浓度的五味子甲素和不同浓度的化疗药物长春新碱合用后体内耐药逆转效应。

To evaluate deoxyschizandrin combinated chemotherapy resistance reversal effect in vivo through the establishment of human oral cancer cell lines in nude mice xenograft model . 4 .

粗蛋白、粗灰分、各种氨基酸和五味子甲、乙素含量呈微弱的下降趋势；

Crude protein , crude ash , all sorts of amino acid and contents of schisantherin A and schisantherin B of which tended to reduce faintly ;

超声-微波协同萃取五味子中五味子甲素的工艺研究（五）织东部盛市同少数民族地区开展扶贫协作。

Study on Extraction of Deoxyschizandrin from Schisandra Chinensis By Ultrasonic Wave and Microwave Organizing the provinces and municipalities in east China to start help-the-poor cooperation with the minority areas .

超临界CO2流体提取五味子中的五味子甲素

Supercritical CO_2 Fluid Extraction of Deoxyschizandrin from Fruits of Schisandra chinensis

并检测其五味子醇甲和甲素等功能成分的含量及酒度、总酸、挥发酸、总酯、透光率、残糖等各项指标。

And test and examine the content of schizandrol A and schisandrin A , alcohol content , total acid , volatile acid , total ester , light transmission rate , residual sugar , and other indicators .

结果显示，五味子醇乙、五味子甲素、五味子酯甲及五酯胶囊溶液可明显抑制他克莫司的吸收外排作用，且五味子甲素的这种抑制作用最强。

The results showed that schisandrol B , deoxyschizandrin , schisantherin A and Wuzhi capsule solution can obviously inhibit uptake and efflux function of tacrolimus , especially deoxyschizandrin most .